Christa Buecker
Molecular Biologist, Transcription enthusiast and stem cell afficionado
Associate Professor at Max Perutz Labs and University Vienna,
- Reposted by Christa BueckerThe (Yoav) Voichek lab has opened its gates at the Weizmann Institute, and is actively recruiting students and researchers at all levels - come explore gene regulation and computational genomics in a fun, friendly sprouting lab 🤗🥼⚗️🧪 www.weizmann.ac.il/plants/voichek
- Congratulations to Dr Feng! Songjie is the genome whisperer who is simply amazing when it comes to editing the genome! And one of the nicest person to have around!
- 🎓 Congrats to Songjie Feng (Bücker lab), who successfully defended his thesis titled “Enhancer cooperativity can compensate for loss of activity over large genomic distances" - well done! 🤩🙌 @univie.ac.at @meduniwien.ac.at
- Reposted by Christa BueckerActivator-promoter compatibility in mammals - Hcfc1 is a key and intrinsically CGI-promoter-specific co-activator that cannot activate non-CGI promoters. Lead by @nemcko.bsky.social & Kevin Sabath in collab. with @plaschkalab.bsky.social @impvienna.bsky.social www.biorxiv.org/content/10.6... (1/2)
- This is such a beautiful piece of work, Filip! Congratulation on the preprint!
- Reposted by Christa BueckerJoin @stirlingchurchman.bsky.social, @moffittlab.bsky.social, @saramostafavi.bsky.social, me and all speakers for the 2026 CSHL meeting Systems Biology: Global Regulation of Gene Expression, March 11-14. Abstract deadline January 9! More infos and registration at meetings.cshl.edu/meetings.asp...
- Reposted by Christa BueckerIntrigued by a long-standing conundrum in small RNA biology—how nuclear Argonaute proteins silence transposons when they *need* target transcription for their own recruitment—we studied the piRNA pathway. And found a hidden RNA-decay axis from Piwi to the RNA exosome.
- RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing biorxiv.org/content/10.64898/20…
- Now that I am off for Christmas, I started my first book for the holidays: Katabasis. And every other page has a few memorable phrases about academia to ponder...
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- Two outstanding group leaders to watch!
- 🧬🎉Join us on Dec 17th for our last session of 2025! 🎉🧬Two fantastic talks on transcriptional regulation: 🔬JB Lalanne on developmental enhancers (and starting a lab in 2025?) 🔬 @rberrens.bsky.social on transposable elements in development 📋Register here: us06web.zoom.us/webinar/regi...
- This looks fantastic! Congratulations to everyone involved!
- An early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost! www.biorxiv.org/content/10.6...
- So deserved! Congratulations, @plaschkalab.bsky.social
- I get it, 90% of students writing to enquire about a research possibility will use ChatGPT. But at least don't end it with Sincerely, [Your Name] I am just so over these emails that say do little, are so generic and just try to flatter me.
- I made an entry in my calendar labelled "Meeting on" I have a slight recollection that it was important and I blocked three hours for it. But I have no idea who I will be talking to, whatever this is about.
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- This is probably my favorite paper of 2025. Beautiful work by @elphegenoralab.bsky.social and @karissalhansen.bsky.social that should be on the top of the reading list for everyone with even a slight interest in gene expression!
- Bah, who needs cohesin if you're at the right place (near). Grover once taught us the difference between near and far (my favourite Sesame Street piece), and now amazing work from @elphegenoralab.bsky.social led by @karissalhansen.bsky.social shows us how: www.science.org/doi/10.1126/...
- Reposted by Christa BueckerWant to analyze the role of endogenous retroviruses in early human development or investigate their regulation in pluripotency and early development for your PhD? Join the lab of @fueyoraquel.bsky.social via the IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/5094682/Fuey...
- Never got to say goodbye! Well, you just have to come back then.
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- It was cold and wet, but nevertheless the lab retreat to Budapest was a success!
- We are excited to participate this year again in the VBC summer school! If you want to work with me and my amazing student Maria, apply!
- The Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Christa Buecker from Max Perutz Labs Vienna is recruiting! Please share training.vbc.ac.at/summer-school/
- Congratulations again, Clemens!
- Messenger RNA is made in the nucleus before it is exported to the cytoplasm for translation. But how are only correctly made mRNAs chosen and remodeled in the nucleus for export? Our new paper investigates the nuclear events leading to human mRNA export. www.nature.com/articles/s41.... (1/4)
- I teach quite a bit, but today was my favourite yearly teaching event: a seminar with @clemensplaschka.bsky.social and @ursulaschoeberl.bsky.social on initiation of transcription, either from a single-molecule or a structural perspective. So much fun and so many insights!
- Congratulations, @alex-stark.bsky.social and @miketilapia.bsky.social ! Loved hearing everything during the @cshasia.bsky.social
- Major new direction in the lab: hacking human cell biology with pathogen effectors (eORFs) - amazing collaboration with @miketilapia.bsky.social lab. Huge congrats to first authors Tomas & He & all co-authors! Check out the pre-print on @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
- Reposted by Christa BueckerThe Vienna BioCenter Summer School 2026 call is now open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Please RT training.vbc.ac.at/summer-school/
- Congratulations, Dr Weykopf! Great achievement andbibambvertain it was a fantastic defense!
- Apply!
- ✨ Passionate about cell biology or biochemistry? Join the Martens Lab as a postdoc to uncover why autophagy stalls at disease-linked protein aggregates - and how to restart it 🧠 Apply here ➡️ tinyurl.com/24dcrcke
- Reposted by Christa Buecker📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...
- Reposted by Christa Buecker🌍Open call: Junior Group Leader positions! Join a world-class biomedical research institute at the heart of the Vienna BioCenter, where curiosity drives discovery. Lead your own lab, pursue bold ideas, and shape the future of science at the IMP: www.imp.ac.at/career/open-...
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- Congratulations, Wendy!
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- Reposted by Christa BueckerMagnus Nordborg of the GMI from the @oeaw.bsky.social has received a Synergy Grant from the @erc.europa.eu. With Richard Durbin and @felipekteixeira.bsky.social, they will investigate how transposable elements shape genome evolution in eukaryotes. Read more: www.oeaw.ac.at/gmi/news-eve...
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- Reposted by Christa BueckerNew paper alert! Scientists in Clemens Plaschka’s lab at the IMP and @juliusbrennecke.bsky.social's lab at @imbavienna.bsky.social solved a decade-old puzzle, uncovering how the information molecule mRNA travels from the cell’s nucleus to its periphery. More: bit.ly/4nHcvys
- Congratulation, @martenslab.bsky.social! great colleague and awesome scientist, now with his third ERC grant!
- Big news! Group leader Sascha Martens has been awarded a prestigious @erc.europa.eu Synergy Grant for the collaborative project DegrAbility to explore how cells can better recycle harmful protein aggregates linked to diseases like Alzheimer’s ➡️ tinyurl.com/2zuz9jcf @univie.ac.at @meduniwien.ac.at
- And we have another open position, this time with a focus on Genome Biology! Join a great community in Vienna to bring your research to the next level!
- 📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Genome Biology. We are particularly interested in researchers investigating the molecular and biophysical mechanisms underlying genome function and regulation. More details ➡️ tinyurl.com/3t7vvdct
- 📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu
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- Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.
- Isa generated numerous KOs of either centrosome or cilia components and analyzed their role in the exit from naive pluripotency, in in vitro rossette assays and in gastruloids. On the way she discovered that simply differentiating the cells does not induce ciliogenesis.
- Reposted by Christa BueckerHappy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
- On my way back from @cshasia.bsky.social meeting on Systems Biology of Gene Regulation. It was fabulous! Small but powerful, fantastic talks and really showcasing the fantastic and impressive science going on in China.
- super cool to see this out! looking forward to now read the details! Congratulations, Yad and @mmasoura.bsky.social
- Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by @mmasoura.bsky.social, to find out! www.biorxiv.org/content/10.1...
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- Yay! Congratulations @blanka-majchrzycka.bsky.social and @danielibrahim.bsky.social ! Good to see this beautiful dissection out !
- What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...
- Reposted by Christa BueckerThe #CSHA meeting on Systems Biology of Gene Regulation & Genome Editing kicks off next Monday! ⏳ Don’t miss your shot to dive into cutting-edge science. 👉 Check out the full program and register now on www.csh-asia.org?content/2767 Location: Suzhou. China | Oct.20-24, 2025
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- Reposted by Christa BueckerIf you’re interested in a PhD that explores the ins and outs of genomes and the nucleus - don’t look further but apply here!!! It is excellent 👌
- 🚨 Please share! We are seeking motivated PhD students who wish to work at the intersection of molecular life sciences and computational sciences. #IMPRS #IMPRSBAC @freieuniversitaet.bsky.social @maxplanck.de Check out our projects and apply by Jan 7th, 2026! www.molgen.mpg.de/IMPRSPhDproj...
- Two more days to apply for the VBC PhD program! Join us in beautiful Vienna to explore exciting scientific questions under fantastic mentorship and in an outstanding training environment!
- Our PhD program offers many training activities and courses for your future career. Check out the range of fully-funded PhD positions in our Autumn call before 10 October 2025: www.vbcphd.at
- That is such great news and Berlin is so lucky to have snatched you up!
- ⚡⚡Excited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work. 🔬🦠I'm hiring at all levels! 🔬🦠Check: www.molgen.mpg.de/fueyo-lab
- Congratulations! nice to see this out!
- 🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China
- Reposted by Christa BueckerCongratulations to @vdeneke.bsky.social & Andreas Blaha @impvienna.bsky.social for their research on vertebrate fertilization, which was awarded this year's ÖGMBT Life Science Research Award in Austria for basic research!
- 🎉Congrats to our @vdeneke.bsky.social, postdoc in the @pauligroup.bsky.social, who has received the 2025 Life Sciences Research Award Austria from the ÖGMBT! She's recognised for her groundbreaking work on the molecular mechanisms of fertilisation: www.imp.ac.at/news/article...
- I have the best lab ever! Today I thought we "just" celebrate the acceptance of @isabellavoelkl.bsky.social paper (more to come in due time...). But my lab surprised me with a 10 year birthday party! And an amazing video from former lab members!
- Congratulations, Raquel and the Wysocka lab! Very cool story! Hope to catch up soon!
- Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK. Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD
