Nick van Gastel
Assistant Prof at UCLouvain, FNRS Research Associate, WELBIO Investigator and Group Leader at de Duve Institute, studying metabolism and microenvironment in hematopoiesis and leukemia.
deduveinstitute.be/research-group/nick…
- Reposted by Nick van GastelCheck out our collaborative Review Article with Dr Momoko Yoshimoto on: HSC-independent and -dependent hematopoiesis: new insights and lineage tracing methods. - Experimental Hematology www.exphem.org/article/S030... @isehsociety.bsky.social @qmbci.bsky.social
- Reposted by Nick van GastelPromoting healthy aging depends on maintaining a robust hematopoietic and immune system, to protect against infections and cancer. Learn more in the #ExpHem Special Issue on Bone Marrow Aging, edited by Atsushi Iwama and Anthony D. Ho ➡️https://buff.ly/NT0sObA
- Reposted by Nick van GastelThe Cre–LoxP system is widely used to study gene function in mice. However, Cre itself can be toxic to cells. Proper controls should always be included to distinguish gene effects from Cre toxicity. www.nature.com/articles/s44...
- Reposted by Nick van GastelThe December Issue includes this article by contributors from @harvardmed.bsky.social that uncovers a method which enables patient-specific iRBC production for in vitro SCD modeling and therapeutic development www.exphem.org/article/S030...
- Reposted by Nick van GastelRead the next brief communication on a group that leveraged single-cell transcriptomics to characterize cell states across the HSPC-myeloid differentiation landscape in LR-MDS www.exphem.org/article/S030.... #ExpHem
- Reposted by Nick van GastelExplore the December #ExpHem Issue now! This issue includes a review covering chromatin remodeling, key transcription factors and more. Read now on www.exphem.org/article/S030....
- Reposted by Nick van Gastel🚨 Abstract Deadline: 15 December! Submit your research for the HExaT Meeting on haematopoietic stem cell expansion, April 23-24, 2026 in York, UK. Don’t miss your chance to present alongside global experts! 👉 Submit Now:
- Reposted by Nick van GastelHave you recently started your own lab or getting ready to open your own lab? You won't want to miss this Creating Your Lab Handbook article in #ExpHem by authors Lev Kats, George Souroullas, Konstantinos Kokkaliaris + more: www.exphem.org/article/S030...
- Reposted by Nick van GastelThe #ExpHem article on malignant hematopoiesis is one you don’t want to miss➡️ZC3H13 facilitates the progression of acute myeloid leukemia through m6A-FOXP1-mediated metabolic reprogramming www.exphem.org/article/S030...
- Reposted by Nick van GastelMixed lineage leukemia fusion oncoproteins can transform cells without additional mutations. This review explores the molecular mechanisms behind leukemia, how these insights led to targeted therapies, and efforts to prevent resistance. Read more: www.exphem.org/article/S030... #ExpHem
- Reposted by Nick van GastelWhether you’re looking to relive the excitement of #ISEH2025 or catch up on what you missed, the New Investigators Committee has gathered the top moments from from our time together in Kumamoto. Read more on iseh.org/Publications...
- Reposted by Nick van GastelCongratulations to our 2024 Young Investigator Article winners, Kristen McSweeney, Miriam Belmonte and @celinanielsen.bsky.social! We're proud to recognize outstanding junior researchers whose work has made an impact in #ExpHem. Read the articles and explore more on www.exphem.org/content/awar....
- Reposted by Nick van GastelASH is coming! Excited to present alongside Vikram Paralkar, Sandra Pinho, Peter Van Galen, and Alison Yeh at the stem cell session of the myeloid workshop on Friday. @ericpietras.bsky.social will be moderating— don’t miss it!
- Reposted by Nick van GastelThe November Issue of #ExpHem is here! Explore the lineup, including Honoring giants in hematopoietic and progenitor cell biology www.exphem.org/article/S030...
- Reposted by Nick van GastelHeme biosynthesis is a really fascinating pathway. We think targeting the enzymes that make heme is a really promising strategy for AML. Check out our paper online today in @cellpress.bsky.social @petermaccc.bsky.social www.cell.com/cell/fulltex...
- Reposted by Nick van GastelAbsolutely! Their work changed the field of experimental hematology forever. Learn more about their legacy in these tributes: www.exphem.org/article/S030... #ExpHem
- It's important to honor great researchers and mentors who have come before us. I'm glad @isehsociety.bsky.social is honoring Drs. Connie Eaves, Makio Ogawa, James Till, and Hal Broxmeyer for their work in HSPC biology. We stand on the shoulders of giants. www.clinicalkey.com#!/content/pl...
- Reposted by Nick van Gastel📢ATTENTION BSKY COMMUNITY - We are expanding!! If you are interested in studying metabolic drivers of cancer progression and therapy resistance using bioengineered models consider joining our group at the Moffitt! Pl. repost, tks moffitt-cancer-center-careers.hctsportals.com/jobs/2115134...
- Reposted by Nick van GastelShowcase your research in Experimental Hematology, the ISEH journal dedicated to transformative hematology science. Take advantage of fast-track options, open access discounts, and global visibility for your work. Learn more: iseh.org/Publications/ExpHem-Journal
- Reposted by Nick van GastelJoin or renew your ISEH membership now for 2026! Stay connected to your society with webinars, networking, awards eligibility, and meeting discounts. 🔗 iseh.org/membership
- Reposted by Nick van GastelCross-species analysis of thymic stroma in mice and humans reveals a subset of mesenchymal cells that are capable of restoring thymic function, which suggests new strategies for thymus regeneration #NBTNV go.nature.com/4r1A8Vp rdcu.be/eOpTg
- Reposted by Nick van GastelEveryone talks about thymic epithelial cells when it comes to T cell development. They play a major role — just not the only one. Our new paper in @natbiotech.nature.com shows the mesenchyme has been quietly pulling strings: rdcu.be/eNF24
- Reposted by Nick van GastelExtremely useful for spectral flow cytometry enthusiasts- thanks @labliston.bsky.social I will share with our core too
- Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold. Want to get a tough sample, like lung, looking like this? Read more! www.biorxiv.org/content/10.1...
- Reposted by Nick van GastelThe Board of Directors call for nominations is open until 13 November. Influence the direction of ISEH and nominate yourself or a colleague! More info on www.iseh.org
- Reposted by Nick van GastelFor my lab lead friends, check out this article of best practices from my colleagues and I on the ISEH Junior PI committee on organizing a leading your team. authors.elsevier.com/c/1lxZ~,6sio...
- Reposted by Nick van GastelOur work detailing the metabolic roles of serum for cancer cell proliferation is now out at JBC, @asbmbjournals.bsky.social! Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process. See here: www.sciencedirect.com/science/arti...
- Reposted by Nick van GastelThere are ✌️ weeks left to register for the FREE 22 October webinar on Responsible AI in Research and Publishing featuringLaura Watts, PhD from @lumanity.bsky.social and @p4sc4l.substack.com from Wiley. Register here 👉 iseh.org/Webinars-Eve...
- Reposted by Nick van GastelInterested in understanding AI better and best practices for using it in research? Don't forget to register for our @isehsociety.bsky.social webinar happening 10/22 @ 9am ET to learn how to use AI responsibly and effectively! iseh.org/Webinars-Eve...
- Reposted by Nick van GastelSurprising finding that standard chemo renders AML resistant to subsequent treatment with menin inhibitors. Published in @isehsociety.bsky.social journal Exp. Hem.: www.exphem.org/article/S030...
- After a stop in Osaka I’m on my way home after #ISEH2025! This was a very successful edition for the MEMI Lab, with 4 posters presented and 2 awards received (@isehsociety.bsky.social New Investigator Award for @celinanielsen.bsky.social and Service Award for myself)! See you in Frankfurt in 2026!
- Reposted by Nick van GastelEpigenetic diagnosis of acute leukemia within two hours from sample receipt 🚀 Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com 📄 www.nature.com/articles/s41... 🧵1/n
- So proud of this work by the @isehsociety.bsky.social Junior Faculty Committee!!! Whether you are just starting your lab or had it for many years, a good Lab Handbook is essential, and we want to help you on the way with this important document…
- Are you a PI who just set up your lab or wants a more efficient daily flow? @isehsociety.bsky.social Junior Faculty Committee (and more) share in #ExpHem to help you build a transparent and functional lab culture. See how a Lab Handbook can benefit you. @nickvangastel.bsky.social bit.ly/3KBFvcQ
- Reposted by Nick van GastelAre you a PI who just set up your lab or wants a more efficient daily flow? @isehsociety.bsky.social Junior Faculty Committee (and more) share in #ExpHem to help you build a transparent and functional lab culture. See how a Lab Handbook can benefit you. @nickvangastel.bsky.social bit.ly/3KBFvcQ
- Reposted by Nick van GastelDon't miss out on this opportunity to ask your burning questions to leading experts in the field! #ISEH2025
- A few tickets left for the #ISEH2025 meet the expert breakfast. Only $35 dollars each! @isehsociety.bsky.social
- Reposted by Nick van GastelA few tickets left for the #ISEH2025 meet the expert breakfast. Only $35 dollars each! @isehsociety.bsky.social
- Reposted by Nick van GastelExcited for tonight's poster session at #ISEH2025 where I will present my latest work on BM secretome remodeling during aging - catch me at poster 3003 if you want to know more! @isehsociety.bsky.social
- Reposted by Nick van GastelPacked house for the kickoff at #ISEH2025 🏯 this morning! We are excited to have you all join us here in Kumamoto.
- #ISEH2025 Two posters from our lab tonight at the poster session: #3171 by Célia Sergi showing how metabolic reprogramming in the niche is required for emergency myelopoiesis during infection! #3113 by myself on how protein palmitoylation controls metabolic flexibility in AML!
- Happening today at #ISEH2025 at 1.30pm in room A3! Come meet editors from journals publishing hematology research and ask anything you want to know about the publishing process. We’ll also discuss “publishing negative results” and “use of AI in writing and reviewing papers”!
- Join the Junior Faculty Career Session: Meet the Editors: Insights from Behind the Scenes. Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯! iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
- #ISEH2025 has started! So excited to be in Kumamoto, Japan 🇯🇵 for what promises to be a really interesting meeting! @isehsociety.bsky.social remains the #1 place for excellent fundamental hematology research and is such an amazing community!
- Reposted by Nick van GastelReady for #ISEH2025 Scientific Session? After 1.5 days of rich, productive discussions, @isehsociety.bsky.social leadership & Board of Directors are all set—with the full program and even the social events lined up! @thekinglab.bsky.social @smckinneyfreeman.bsky.social @nickvangastel.bsky.social
- Reposted by Nick van GastelFor our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Nick van GastelJoin the Junior Faculty Career Session: Meet the Editors: Insights from Behind the Scenes. Attend this free session during the lunch hour on Thursday, 25 September at #ISEH2025 🏯! iseh.org/Annual-Meeting/54th-Annual-Meeting/Registration
- Reposted by Nick van Gastel
- Reposted by Nick van GastelOnline now: OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis
- Reposted by Nick van GastelThe ISEH just launched a brand new website! Check it out and join our society today to network with your colleagues and keep abreast of the latest advances in basic and translational experimental hematology research! iseh.org
- Reposted by Nick van Gastel@vanessascanlon.bsky.social from @uconnhealth.bsky.social is excited for the Junior Faculty Networking Workshop taking place the night before #ISEH2025 🏯 begins. Join fellow junior faculty for a night of networking and fun, you may even win a prize! Learn more --> www.iseh.org/2025SocialNetworking
- Reposted by Nick van GastelThis week on #SimplyBlood🩸 we're delighted to share an inspiring conversation with Dr. Toshio Suda, Editor-in-Chief of ExpHem! @keisukeito-lab.bsky.social had the unique opportunity to discuss the journal’s evolution including its future vision and ongoing efforts➡️https://www.simplyblood.org/
- Reposted by Nick van GastelIron-loaded Red Blood Cells undergo a lipid peroxidation process akin to ferroptosis during storage in the blood bank. We now show that they also harbor a functional GPX4, and common SNPs, genetic or pharmacological manipulation impact transfusion outcomes www.sciencedirect.com/science/arti...
- Reposted by Nick van GastelThe #ISEH2025 🏯 program is here and packed with cutting-edge science. Hear from Scientific Program Chair @milsommick.bsky.social for a behind the scenes look at how it came together and what to expect in Kumamoto www.simplyblood.org
- Reposted by Nick van GastelT-minus two days to snag a talk slot at ISEH 2025 via a late-breaking abstract submission
- 🚨 There is ONE WEEK left to submit a late-breaking abstract for #ISEH2025 🏯! Submit your research by 28 July for a chance at a short talk or poster presentation. www.iseh.org/2025abstracts
- Reposted by Nick van Gastel🚨 There is ONE WEEK left to submit a late-breaking abstract for #ISEH2025 🏯! Submit your research by 28 July for a chance at a short talk or poster presentation. www.iseh.org/2025abstracts
- Reposted by Nick van Gastel#ISEH2025 🏯 is just around the corner and hundreds of scientists will be heading to Kumamoto, Japan, for four days of education, networking, and sightseeing. Register by 7 August for the lowest rates to join us! www.iseh.org/2025Registration
- Reposted by Nick van GastelThe July #PreprintWatch features 25 fresh preprints that span hematopoietic development, leukemogenesis, and the latest in tech development. Plus, a video chat with @abattacks.bsky.social - one of our featured community submitters! Explore on www.simplyblood.org
