did:plc:73sj55cnrnzoqgipe35awzku
Instructor in the Scadden lab thinking about how to make the thymus and people younger
- Everyone talks about thymic epithelial cells when it comes to T cell development. They play a major role — just not the only one. Our new paper in @natbiotech.nature.com shows the mesenchyme has been quietly pulling strings: rdcu.be/eNF24
- Thymic mesenchymal cells produce key factors that attract and organize T cell progenitors. Lose the mesenchyme — through aging or damage — and T cell output drops.
