Nature Genetics
Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. Part of @natureportfolio.bsky.social
Repost/like=interesting/relevant, not necessarily endorsement.
- Reposted by Nature Genetics🚨The paper from my postdoc in @graeffjohannes.bsky.social’s lab at @epfl-brainmind.bsky.social is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing. www.nature.com/articles/s41...
- 📢OUT TODAY @natgenet.nature.com 📰Limited overlap between genetic effects on disease susceptibility and disease survival. By Zhiyu Yang, Nina Mars, Andrea Ganna and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT @natgenet.nature.com 📰Bryophytes hold a larger gene family space than vascular plants. By Shanshan Dong, Yang Liu and colleagues. ⬇️ www.nature.com/articles/s41...
- ✨Don't miss the N&V✨ 📰The dawn of bryophyte genomics is here. By Giacomo Potente, Yuling Yue & Péter Szövényi. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰DNA methylation influences human centromere positioning and function. By Catalina Salinas-Luypaert, @dfachinetti.bsky.social, @naltemose.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 💫 Don't miss the N&V by Sylvia Erhardt. 📰Dipping into the function of DNA methylation at centromeres. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Rapid epigenomic classification of acute leukemia By Til L. Steinicke, Gabriel K. Griffin, Volker Hovestadt and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects. By Konrad J. Karczewski, Alicia R. Martin and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks. By Ching-Huang Ho, John P. Ray and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰 Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes. By Camiel M. van der Laan, Dorret I. Boomsma and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢📢REVIEW PUBLISHED TODAY @natgenet.nature.com 📰Advancing biological understanding of cellular senescence with computational multiomics. By Sheng Li, SenNet Consortium, and colleagues! ⬇️ www.nature.com/articles/s41...
- 📢OUT @natgenet.nature.com 📰DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution. By Francisco Gimeno-Valiente, Nnennaya Kanu and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT @natgenet.nature.com 📰Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions. By Aliza P. Wingo, Thomas S. Wingo and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢The September issue of @natgenet.nature.com is out! Featuring: ✅multiomic analysis in NSCLC ✅ancestral recombination graphs with SINGER ✅mutational landscape of TNBC in African American women ✅scDNAme&3Dgenome atlas of human SAT ✅avena super-pangenome &more! ⬇️ www.nature.com/ng/volumes/5...
- 📢 OUT TODAY @natgenet.nature.com 🐄A multi-tissue single-cell expression atlas in cattle🐄 By Bo Han, Dongxiao Sun, Lingzhao Fang and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Mutational landscape of triple-negative #breastcancer in African American women. By Song Yao, John D. Carpten and colleagues. ⬇️ www.nature.com/articles/s41...
- ✨PUBLISHED @natgenet.nature.com 📰Tamoxifen induces PI3K activation in #uterinecancer. By Kirsten Kübler, Gad Getz, Rinath Jeselsohn and colleagues. ⬇️ www.nature.com/articles/s41...
- 👉Don't miss the Research Briefing! 📰Mystery of tamoxifen-associated uterine cancer uncovered. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue. By Zeyuan Johnson Chen, Päivi Pajukanta and colleagues. ⬇️ www.nature.com/articles/s41...
- Reposted by Nature Genetics📣New @natgenet.nature.com The Hartwig group @mpipz.bsky.social and colleagues @hhu.de unveil a scalable way to map plant genomic "switches" - these overlooked regions hold huge promise for crop breeding & climate resilience. 👉http://bit.ly/41BmCwD #plantsci www.nature.com/articles/s41...
- 🎉PUBLISHED @natgenet.nature.com 📰Tracing the evolution of single-cell 3D genomes in Kras-driven #cancers. By Miao Liu, @muzumdarlab.bsky.social, @sstevenwang.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 💫PUBLISHED @natgenet.nature.com 📰Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states. By Kaden M. Southard, @normanlab.bsky.social and colleagues! ⬇️ www.nature.com/articles/s41...
- ✨Don't miss the Research Briefing✨ 📰Recreating fibroblast diversity in vitro by activating transcription factors. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression. By Anjali Chawla, Gustavo Turecki and colleagues. ⬇️ www.nature.com/articles/s41...
- Nature Genetics editor Margot Brandt will be attending the @fusionconf.bsky.social “Endogenous Retrotransposable Elements & Human Diseases Conference” bit.ly/45iiYbY. Please feel free to reach out to her if you would like to discuss your research!
- Reposted by Nature Genetics#NatMicroPicks Decoding Shigella’s Virulence Blueprint 🦠🧬 Combining organoid infection models with genome-wide mutagenesis allows mapping the full set of Shigella genes required for human gut colonization www.nature.com/articles/s41... @sellinlab.bsky.social @natgenet.nature.com
- 📢 PUBLISHED @natgenet.nature.com 📰The LISTEN principles for genetic sequence data governance and database engineering. A Perspective by Colin J. Carlson, @ctrlalttim.com and colleagues. ⬇️ www.nature.com/articles/s41...
- 🧪 What if we could share genetic sequences in a way that is equitable, and works for the greater good? Now in @natgenet.nature.com, we establish a framework for the open sharing of digital sequence information 🧬, compatible with FAIR, and designed to support access and benefit-sharing. 🧵
- 📢PUBLISHED @natgenet.nature.com 📰Large-scale genome-wide analyses of stuttering. By Hannah G. Polikowsky, Jennifer E. Below and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Massively parallel immunopeptidome by DNA sequencing provides insights into #cancer antigen presentation. By Quanming Shi, Howard Y. Chang and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢PUBLISHED @natgenet.nature.com 📰Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution. By Ryuya Edahiro, Atsushi Kumanogoh, Yukinori Okada and colleagues. ⬇️ www.nature.com/articles/s41...
- Reposted by Nature GeneticsSo happy to see the illustration of our work featured on the cover of @natgenet.nature.com 😍 It represents digits desintegrating into viral like particles. Thank you so much @annaamonaco.bsky.social for making this design!
- 💫The July issue of @natgenet.nature.com is out! Featuring: ✅retrotransposons in limb malformation and cancer ✅single-cell Micro-C ✅long-term effects of chemotherapy on normal blood cells ✅blood regulatory variation map in South Africans And more! ⬇️ www.nature.com/ng/volumes/5...
- 💫The July issue of @natgenet.nature.com is out! Featuring: ✅retrotransposons in limb malformation and cancer ✅single-cell Micro-C ✅long-term effects of chemotherapy on normal blood cells ✅blood regulatory variation map in South Africans And more! ⬇️ www.nature.com/ng/volumes/5...
- 📢OUT TODAY @natgenet.nature.com 📰Improved multiancestry fine-mapping identifies cis-regulatory variants underlying molecular traits and disease risk. By @zeyunlu.bsky.social, @nmancuso.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT TODAY @natgenet.nature.com 📰 #Singlecell and #spatialtranscriptomics reveal mechanisms of radioresistance and #immune escape in recurrent nasopharyngeal #carcinoma. By Rui You, Mingyuan Chen and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT TODAY @natgenet.nature.com 📰A contextual genomic perspective on #physicalactivity and its relationship to #health, #wellbeing and #illness. By Marco Galimberti, Joel Gelernter and colleagues. ⬇️ www.nature.com/articles/s41...
- ✨Take a look at this Perspective OUT TODAY @natgenet.nature.com 📰Toward improving multiomic research in understudied cereals. By Fanjing Yang, Chu-Yu Ye and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy. By Jie Liu, @kellybolton.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 🎉ONLINE @natgenet.nature.com 📰Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes. By @julianeg.bsky.social, Giulia Cova, Stefan Mundlos and colleagues. ⬇️ www.nature.com/articles/s41...
- 💫Don't miss the N&V💫 📰A retrotransposon caught red-handed in a curious case of missing digits. By Youjia Guo & Andrew J. Modzelewski. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers. By Tim Arnoldus, Daniel S. Peeper and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰"The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types" By Pui Ying Chan, @davidjadams.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT TODAY @natgenet.nature.com 📰Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs. By Honggui Wu, @Xiaoliang Sunney Xie and colleagues. ⬇️ www.nature.com/articles/s41...
- ✨OUT TODAY @natgenet.nature.com 📰Disruption of TAD hierarchy promotes LTR co-option in #cancer. By Elissa W. P. Wong, Ping Chi and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰Multi-omic analysis of gallbladder #cancer identifies distinct tumor microenvironments associated with disease progression. By Tao Zhou, Lei Chen and colleagues. ⬇️ www.nature.com/articles/s41...
- 💫Don't miss the N&V💫 📰Spatial and temporal dynamics in progressive gallbladder cancer. By Colm J. O’Rourke & Jesper B. Andersen ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰Single-cell and spatial transcriptomics of stricturing #Crohn’s disease highlights a fibrosis-associated network. By Lingjia Kong, @thexavierlab.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢OUT TODAY @natgenet.nature.com 📰Predicting resistance to chemotherapy using chromosomal instability signatures. By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...
- 🚨Chemo treatment upgrade!🚨 Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
- 📢ONLINE @natgenet.nature.com 📰A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen. By @mldm.bsky.social, @lbarquist.bsky.social, Mikael E. Sellin and colleagues. ⬇️ www.nature.com/articles/s41...
- 💫Don't miss the N&V💫 📰Organoid models advance dysentery control. By Sydney L. Miles & Serge Mostowy. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰Linking regulatory variants to target genes by integrating single-cell multiome methods and genomic distance. By Elizabeth Dorans, Alkes L. Price and colleagues. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰A map of blood regulatory variation in South Africans enables GWAS interpretation. By Stephane E. Castel, Michèle Ramsay and colleagues. ⬇️ www.nature.com/articles/s41...
- Reposted by Nature GeneticsAmazing to have our work featured on the cover of the latest issue of @natgenet.nature.com! The artwork, like the science, is a collaborative creation with everyone’s fingerprints 🎉 www.nature.com/articles/s41...
- 💫The June issue of @natgenet.nature.com is live! Featuring: ✅APOBEC3 mutagenesis in #breastcancer ✅GWAS of long #COVID ✅snRNA gene mutations in neurodevelopmental disorders ✅NLR genes in wheat resistance to pathogens And much more! ⬇️ www.nature.com/ng/volumes/5...
- 💫The June issue of @natgenet.nature.com is live! Featuring: ✅APOBEC3 mutagenesis in #breastcancer ✅GWAS of long #COVID ✅snRNA gene mutations in neurodevelopmental disorders ✅NLR genes in wheat resistance to pathogens And much more! ⬇️ www.nature.com/ng/volumes/5...
- 📢ONLINE @natgenet.nature.com 📰Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease highlight shared and tissue-specific effects. By the Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium. ⬇️ www.nature.com/articles/s41...
- 📢ONLINE @natgenet.nature.com 📰 High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancer. By Michelli Faria de Oliveira, Sarah E. B. Taylor and colleagues. ⬇️ www.nature.com/articles/s41...