Prof Cynthia Whitchurch FAA🏳️🌈
Microbiologist, interested in alternate bacterial lifestyles - cell wall deficiency, biofilms, AMR
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- We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing. It’s not a toxin. It’s metabolism. The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place. doi.org/10.1126/sciadv.aeb5297
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈#NatMicroPicks How drugs reshape the gut microbiome? 💊🦠 Screening 707 drugs in gut microbial communities reveals nutrient competition as the key driver of compositional and metabolic shifts. #MicroSky #MicrobiomeSky 🦠 www.cell.com/cell/fulltex...
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- Fortuitous timing for my NTU-SBS seminar to land in World Antimicrobial Awareness Week #WAAW. I took the opportunity to showcase our research into alternate bacterial lifestyles and how we are leveraging this understanding to develop innovative approaches to combat AMR 🧫🧪 @scelse.bsky.social
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Between 2018–2023, antibiotic resistance increased in over 40% of the pathogen–antibiotic combinations monitored, with an average annual rise of 5–15%. Resistance is highest in the WHO South-East Asian & Eastern Mediterranean Regions, where 1 in 3 reported infections were resistant 👉 bit.ly/438Ta1u
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Our first effort exploring gut bacteria-extracellular ATP interactions is published! We show that eATP rewires gene expression and physiology in harmless and pathogenic bacteria, impacting production of bioactive metabolites, antimicrobial sensitivity, and virulence. A 🧵 www.cell.com/cell-reports...
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈We have a PhD opportunity available in our group @johninnescentre.bsky.social through the NRP Doctoral Training Partnership. Help us uncover the Hidden Diversity of Bacterial NLRs. Start date: October 2026. For more information and how to apply👉 biodtp.norwichresearchpark.ac.uk/projects/bey...
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈My lab @scelse.bsky.social NTU is growing! Fun evening out with the team, I'm so fortunate to work with such a great group of scientists!
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Quite an interesting protein search AI model combining sequence, structure, and function text - faster and more accurate than similarity searches. Who has tried it🤩🙌? Only a few secs to search bacterial TFs and integrases #microsky 🧬🧪 www.nature.com/articles/s41...
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social&@chipericson.bsky.social trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬 www.biorxiv.org/content/10.1...
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Holy moly
- Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope www.nature.com/articles/s41... #jcampubs
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Finally out, such an awesome piece of work, very proud of this one: www.cell.com/cell-systems... #MicroSky
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈🐟💊🦠Our new study in @natwater.nature.com 🐟💊🦠 "Microbial risks triggered by oral administration of antibiotics in fish aquaculture persist long after the legally mandated antibiotic withdrawal time" www.nature.com/articles/s44... #microsky #amr 1/8
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈For our scientists. By @ellecordova.bsky.social
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈MIT News: news.mit.edu/2024/human-g... — Sharing our new publication in Cell Genomics: cell.com/cell-genomic... about why our human gut microbiome rarely updates its CRISPR defense systems!
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Pleased to welcome my new colleague from SBS @ NTU Singapore, Anni Zhang @annizlab.bsky.social, to the platform. She is a dynamic addition to our school, and it's always a pleasure to discuss science with her. Looking forward to her contributions here. Find more about her lab 👇
- Hi everyone, I'm a bioinformatician & microbiologist. My new lab @Nanyang Technological University uncovers diverse microbial mechanisms (regulatory networks, selective sweeps, host-microbe interactions, ...) via machine learning! genomiverse.net
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Hi everyone, I'm a bioinformatician & microbiologist. My new lab @Nanyang Technological University uncovers diverse microbial mechanisms (regulatory networks, selective sweeps, host-microbe interactions, ...) via machine learning! genomiverse.net
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈An inspiring read! academic.oup.com/genetics/adv... A beautiful historical perspective on Ester Lederberg's legacy from @ccwendling.bsky.social & @zacharybailey.bsky.social
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈📣 Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up package. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack Register HERE: lnkd.in/gSy5qpA7
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈😳 #phage #phagesky #microsky Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system: www.cell.com/cell-host-mi...
- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Nice to see a follow up story on @drlauranolan.bsky.social Pseudomonas aeruginosa T6SS toxin Tse8
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Our latest efforts to understand Enterococcal wound infection. In long-term collaboration with @gthibault.bsky.social, we discovered how E. faecalis makes extracellular ROS - via EET!⚡️Which in turn dysregulates host UPR to delay wound healing. Led by @aarontan.bsky.social - his videos below are 🤩!
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- Reposted by Prof Cynthia Whitchurch FAA🏳️🌈Want to learn more about dissecting microbial community interactions across scales using the corrinoid model? Check out this @annualreviews.bsky.social of Microbiology article from our lab. Congrats to co-first authors Zoila and Becky! #microsky www.annualreviews.org/content/jour...