Beatriz Beamud
🧪 Bacteria & Mobile Genetic Elements 💻 Synthetic Biology Group @institutpasteur 👩🔬 PhD @GVAfisabio @i2sysbio
- Reposted by Beatriz BeamudBacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive. Here we explore the conjugative capacity of these mysterious Genomic Islands. www.biorxiv.org/content/10.6...
- Reposted by Beatriz BeamudBacterial genomes encode a rich repertoire of antiphage systems, but we still know surprisingly little about when these systems are actually expressed. In this preprint, Lucas Paoli et al, ask what shapes antiphage systems expression in native contexts. www.biorxiv.org/content/10.6...
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- Reposted by Beatriz Beamud📣 New preprint from us at phagefoundry.org 📣 A solid machine learning framework & to predict strain-level phage-host interactions across diverse bacterial genera from genome sequences alone. Avery Noonan from the Arkin Lab led this massive effort www.biorxiv.org/content/10.1...
- Reposted by Beatriz Beamud@prczhaoyansong.bsky.social’s deep dive into the dark matter of compost communities is now out 🎉 Genomic islands hijack jumbo phages—whose capsids enable transfer of large tracts of DNA—shedding new light on the scale & scope of phage-mediated gene flow 😎 www.pnas.org/doi/10.1073/...
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- Can we exploit past phage infection events (prophages) to decipher the specificity of phage receptor-binding proteins such as depolymerases?🔎 Happy to share our recent work at @natcomms.nature.com 🔽 #microsky #phagesky www.nature.com/articles/s41...
- Massive thanks to @concha-eloko.bsky.social @pilardomingoc.bsky.social and @rafa-sanjuan.bsky.social to make it possible!
- Any group would be incredibly lucky to have her!
- Reposted by Beatriz BeamudHow complex functions, with important physiological and evolutionary impacts get repeatedly and efficiently transferred across genomes? That’s what we explored using one of the fastest-evolving loci in Bacteria: the capsule locus. The paper: www.biorxiv.org/content/10.1... Thread👇
- Very well-deserved @dbikard.bsky.social, congratulations!!! 🙌🙌 It's great to learn from the best! 🥳
- 🎉 Congratulations to David Bikard @pasteur.fr on his 2025 @embo.org Gold Medal win! 🧬 He's pioneering phage-CRISPR tools to edit gut #bacteria in vivo, reshaping the #microbiome from within and opening the door to targeted therapies. 👉 europa.eu/!HQbHTw 👉 europa.eu/!KtWf33 @dbikard.bsky.social
- Massive effort lead by the amazing @fabbenz.bsky.social to discuss the present and future of CRISPR-based antimicrobials ⚡
- Reposted by Beatriz Beamud1/6 Excited to share our review 🚀 🧬 CRISPR–Cas therapies targeting bacteria! #MicroSky
- Reposted by Beatriz BeamudOur review on recent advances in #PhageTherapy against Klebsiella pneumoniae is out! We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning. #microsky doi.org/10.1371/jour...
- Reposted by Beatriz BeamudAnd here it is, the completed BASEL collection finally published as early access in @plosbiology.org - see the thread for more details. 🤗🧬🎣
- Reposted by Beatriz BeamudDo restriction-modification systems shape plasmid sequence composition? A group of plasmid-aficionados, led by Liam Shaw, started to explore this during the 2023 @embo.org Workshop on Plasmids in Trieste. Happy to have contributed to this work and be part of such a great team!
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