Julie Le Bris
PhD student interested in microbial evolution and ecology🧬 @Institut Pasteur
#Klebsiella #MicroSky
- Reposted by Julie Le Bris🧬 Dive into the small proteome of Methanosarcina mazei (across 5 conditions)! A key resource by @schmitzstreitslab.bsky.social @uni-kiel.de for uncovering #smallproteins functions, motifs and proteoforms in #archaea. 👉 buff.ly/HJOi3E0
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- Reposted by Julie Le BrisMy team at @cbitoulouse.bsky.social is recruiting a postdoc #bioinformatics with solid experience in metagenomic analyses. Interest in evolution, ecology & MGEs is important. The offer stands until the perfect candidate is found, and it could be you 🫵 🔁 🙏 #microSky #phagesky #UTIsky @cnrs.fr
- Reposted by Julie Le Bris@archaellum.bsky.social lab reveals how #cdiAMP and 4 RCK proteins shape osmotic stress responses in H. volcanii 🧬🦠. In highly halophilic #archaea, c-di-AMP coordinates ion balance and cell volume—mirroring bacterial strategies for environmental stress adaptation. 👉 buff.ly/ApWkCtg
- Reposted by Julie Le BrisReview –by J. Yuan @mpimicrobiomarburg.bsky.social, HG. Koch & B. Berghoff— highlights bacterial small membrane proteins (SMPs) 🧫: from regulating membrane targets and insertion pathways to toxin roles. SMPs also offer potential as tools and templates for new antibiotics.💊 👉 buff.ly/9UzCwF2
- Reposted by Julie Le BrisAs 2026 begins, the EAM, @Vdlorenzo.bsky.social, Paul B. Rainey and many others remind us the urgency of renewing support to Society Journals and, taking action to reward quality research and curb predatory publishing. 👉 buff.ly/V36xgMO 👉 buff.ly/T8QE90G
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- Reposted by Julie Le BrisEverything you need to explain AMR to family and friends-12: @pablolaborda.bsky.social @crisherencias.bsky.social @pharmageddon.bsky.social @ecdc.europa.eu @eberllab.bsky.social @klebclub.bsky.social @olayarendueles.bsky.social the ESKAPE Rogues www.imili-eah.com/prod-api/pro...
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- Reposted by Julie Le BrisDe-DUFing the DUFs 🧩 @franznarberhaus.bsky.social lab uncovers how small DUF1127 proteins regulate #phosphate uptake by binding the sensor kinase PhoR. Their conserved role from Agrobacterium to E. coli highlights how even small DUFs can shape bacterial physiology 🦠 buff.ly/jJd9Eho
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- Reposted by Julie Le BrisNew tools unlock #Bdellovibrio bacteriovorus’s predatory secrets 🦠. By combining inducible gene expression with #CRISPRi-mediated depletion for precise control of essential genes, @lalouxlab.bsky.social uncovered new insights into its unique lifecycle and cell division. buff.ly/FcDzAY4
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- Reposted by Julie Le BrisCyril Anjou, 2e candidat au prix de thèse nous a présenté ses travaux sur les rôles physiologiques des systèmes thioredoxine de Clostridioides difficile, impliqués dans les étapes du cycle de vie de la bactérie, ainsi que sur l’intérêt thérapeutique potentiel de la modulation de leur expression.🦠
- Reposted by Julie Le Bris🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫 Thread coming soon!
- Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection biorxiv.org/content/10.1101/202…
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- Reposted by Julie Le BrisHow do bacteria choose what type of defences to use against phages? We explored that question in the last paper I worked on as a postdoc at the Uni of Exeter @uniofexeteresi.bsky.social with Stineke van Houte, Stefano Pagliara and Edze Westra (not on Bluesky) doi.org/10.1098/rstb...
- How complex functions, with important physiological and evolutionary impacts get repeatedly and efficiently transferred across genomes? That’s what we explored using one of the fastest-evolving loci in Bacteria: the capsule locus. The paper: www.biorxiv.org/content/10.1... Thread👇
- 🧬 Beyond virulence, capsule changes shape host evolution and is tied to core metabolism. This suggests epistasis, yet their diversity and turnover argue for modularity. @klebclub.bsky.social #microsky
- Reposted by Julie Le BrisCheck out @julielebris.bsky.social’s thread on our latest manuscript describing phenotypic heterogeneity in capsule production in Klebsiella & Acinetobacter @klebclub.bsky.social This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social #microsky #phagesky
- Delighted to share our recently published work! Ever wondered how Klebsiella (and others) deals with capsule production’s costs ? The paper: journals.asm.org/doi/10.1128/... Thread👇
- Delighted to share our recently published work! Ever wondered how Klebsiella (and others) deals with capsule production’s costs ? The paper: journals.asm.org/doi/10.1128/... Thread👇
- 🔬Microscopy with India ink staining showed clonal cells make varying amounts of capsule—unlike P. fluorescence’ ON/OFF switch, it’s a continuous phenotype.
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- Reposted by Julie Le Bris#phagesky I am looking for phages infecting Streptococcus pneumoniae to test a phenotype - does anyone have some and willing to share ? Repost appreciated :)
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- Thrilled to see our review out! Great team effort with @olayarendueles.bsky.social and @dariavantyne.bsky.social, @nathaliechen.bsky.social, Adeline Supandy #VanTyneLab @pghphageprogram.bsky.social
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