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Nature Reviews Bioengineering

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An online-only journal from @natureportfolio.bsky.social publishing high-quality Reviews, Perspectives and Comments across all areas of bioengineering nature.com/natrevbioeng/

Joined November 2024

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Nature Reviews Bioengineering natrevbioeng.nature.com · Feb 5
The status of extracellular vesicles as drug carriers and therapeutics
The status of extracellular vesicles as drug carriers and therapeutics

Nature Reviews Bioengineering, Published online: 05 February 2026; doi:10.1038/s44222-026-00405-xExtracellular vesicles (EVs) are emerging as biocompatible carriers for targeted drug delivery, yet challenges in yield, cargo loading and biodistribution persist. In this Review, key trends from over a decade of research are analysed, comparing EVs with lipid-based systems and outlining strategies for improving therapeutic translation and reporting standards.

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Nature Reviews Bioengineering natrevbioeng.nature.com · Feb 3
ICYMI: Design principles of lipid nanoparticles for RNA delivery
Design principles of lipid nanoparticles for RNA delivery

Nature Reviews Bioengineering, Published online: 02 February 2026; doi:10.1038/s44222-026-00401-1Lipid nanoparticles can serve as carriers for RNA therapies, enabling efficient encapsulation, cellular uptake and controlled protein expression. This Review explores their design principles, key components, physicochemical properties and therapeutic potential, highlighting how formulation parameters influence delivery performance.

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Nature Reviews Bioengineering natrevbioeng.nature.com · Feb 2
Design principles of lipid nanoparticles for RNA delivery
Design principles of lipid nanoparticles for RNA delivery

Nature Reviews Bioengineering, Published online: 02 February 2026; doi:10.1038/s44222-026-00401-1Lipid nanoparticles can serve as carriers for RNA therapies, enabling efficient encapsulation, cellular uptake and controlled protein expression. This Review explores their design principles, key components, physicochemical properties and therapeutic potential, highlighting how formulation parameters influence delivery performance.

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