Arnd Roth
Computational neuroscience and connectomics
- Reposted by Arnd RothEpisode #37 in #TheoreticalNeurosciencePodcast: On reproducibility of modeling and 10 years with the Potjans-Diesmann network model - with Hans Ekkehard Plesser theoreticalneuroscience.no/thn37 How can replication crises be avoided in computational neuroscience?
- Reposted by Arnd RothThrilled that our paper is out today in Nature! www.nature.com/articles/s4...
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- Reposted by Arnd RothEpisode #33 in #TheoreticalNeurosciencePodcast: On computational neurotechnology for the clinic – with Anthony Burkitt, Nada Yousif and Esra Neufeld theoreticalneuroscience.no/thn33 I hosted a panel debate on the topic at CNS2025 in Florence in July. @cnsorg.bsky.social
- Using a new genetically-encoded voltage indicator in an all-optical approach to measure synaptic plasticity in awake behaving mice. Great work by @jacquescarolan.bsky.social and colleagues. Check out www.nature.com/articles/s41...
- Check this out if you're interested in causal neuroscience and/or brain-machine interfaces www.cell.com/cell-reports...
- Reposted by Arnd RothEpisode #32 in #TheoreticalNeurosciencePodcast: On IIT and adversarial testing of consciousness theories – with Christof Koch theoreticalneuroscience.no/thn32 Christof, a developer of the IIT theory for consciousness, explains IIT and recent testing against the GNWT theory.
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- Reposted by Arnd RothWant to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply
- X Latin American School on Computational Neuroscience – LASCON 2026 University of São Paulo, Brazil January 5-30, 2026 Application Deadline: October 4, 2025 sisne.org/en/lascon-x/
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- Reposted by Arnd RothA new study led by @timothysit.bsky.social reveals that different layers of mouse V1 integrate visual and non-visual signals differently. Activity is dominated by vision (or spontaneous fluctuations) in L2/3 and by movement in L5. This leads to different geometries. www.biorxiv.org/content/10.1...
- Reposted by Arnd RothTogether with @repromancer.bsky.social, I have been musing for a while that the exponentiated gradient algorithm we've advocated for comp neuro would work well with low-precision ANNs. This group got it working! arxiv.org/abs/2506.17768 May be a great way to reduce AI energy use!!! #MLSky 🧪
- Reposted by Arnd RothEpisode #29 in #TheoreticalNeurosciencePodcast: On the philosophy of simplification in computational neuroscience - with Mazviita Chirimuuta and Terrence Sejnowski theoreticalneuroscience.no/thn29 What are the pitfalls when simplifying? Panel debate at FENS meeting in Oslo. @fens.org
- Reposted by Arnd RothThere are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.
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- Reposted by Arnd RothDoes neural computation feel like something? In our new paper, we explore a paradox: if you replay all the neural activity of a brain—every spike, every synapse—does it recreate conscious experience? 🧠 doi.org/10.3389/fnin...
- Reposted by Arnd RothEpisode #28 in #TheoreticalNeurosciencePodcast: On whole-cell modeling of bacteria – with Markus Covert theoreticalneuroscience.no/thn28 In 2020 a model of E. coli with 10000 equations and 19000 parameters was presented by the guest. How are such models made?
- Reposted by Arnd RothDelighted to join the Royal Society of London for Improving Natural Knowledge! It's been in the news since 1660, and more so lately. Grateful to all my collaborators over the years.
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- Reposted by Arnd Roth"Science is an investment. We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world." — President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷
- Reposted by Arnd Roth#preprint: We mapped the structure and function of olfactory bulb circuits with in vivo 2-photon microscopy and synchrotron #Xray holographic nanotomography. doi.org/10.1101/2025... @yuxinzhang.bsky.social @andreas-t-schaefer.bsky.social @apacureanu.bsky.social @crick.ac.uk @esrf.fr
- Reposted by Arnd RothLinking function and structure at scale with X-rays - and several times over. Massive congratulations to the team @yuxinzhang.bsky.social, @carlesbosch.bsky.social, @apacureanu.bsky.social @esrf.fr, @crick.ac.uk and all our collaborators.
- My PhD project is out as a preprint! We combined 2P and synchrotron X-ray to understand mouse olfactory bulb circuits, linking physiology to structure in 3 animals! doi.org/10.1101/2025... 🙌 @carlesbosch.bsky.social, @apacureanu.bsky.social, @andreas-t-schaefer.bsky.social, @esrf.fr, @crick.ac.uk
- Reposted by Arnd RothEpisode #27 in #TheoreticalNeurosciencePodcast: On construction and clinical use of multipurpose neuron models – with Etay Hay theoreticalneuroscience.no/thn27 How are multipurpose neuron models made and used to explore differences between healthy and depressed brains?
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- Check out: physics-based modelling of locomotion in Drosophila
- Both scary and exciting
- Reposted by Arnd Rotha friend sent me this one
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- Reposted by Arnd RothEpisode #26 in #TheoreticalNeurosciencePodcast: On the population code in visual cortex – with Kenneth Harris theoreticalneuroscience.no/thn26 How do groups of neurons together encode information to balance the needs for efficiency and robustness?
- Reposted by Arnd RothPhase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks. Beautiful work by @stefanieliebe.bsky.social
- Science Alert 🚨: Our paper is now out in @natureneuro.bsky.social - We show that the firing phase of neurons in human MTL doesn’t reflect the order of events, challenging a long-standing theory of human memory. nature.com/articles/s41593-025-01893-7
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- Reposted by Arnd Roth✨ Announcing a new glutamate indicator - iGluSnFR4! ✨ Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses. More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1... 🧠📈
- Reposted by Arnd RothFigured I’d hop on here today for the 15th anniversary of the Affordable Care Act. With everything going on right now, it’s easy to feel like regular folks can’t make a difference – but the ACA is a reminder that change is possible when we fight for progress.
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- Reposted by Arnd RothBy attacking science: We are less safe because science informs national security and medical care. We are less prosperous because science drives innovation and economic benefit. We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.
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- If you want to move to Europe for no particular reason...
- Reposted by Arnd RothThe International Brain Laboratory reproducibility platform paper is now published at eLife. An amazing effort by many different labs and individuals to understand and improve the reproducibility of electrophysiological measurements in mice. 🧠
- This is just stupid (unless you want to suck up to other totalitarians)
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- Reposted by Arnd RothAre you using GCaMP8 or are planning to switch from GCaMP6? Then check out this new preprint from our lab! www.biorxiv.org/content/10.1... - Calcium imaging - GCaMP8 vs. GCaMP6 - Spike inference - Imaging + ephys ground truth With F. Helmchen, K. Svoboda, M. Rozsa & X. Fang.
- "It Can't Happen Here"
- Reposted by Arnd RothThere are concerns that Bluesky's impact has faded since the initial hype. This is false. That impression results from reading headlines about social media instead of the hard data. The five HIGHEST points of Bluesky posts mentioning research all occur in the last 2 weeks.
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- Highly recommended
- Abstract submission is open for UK Neural Computation 2025 @ Imperial College (9-11 July) neuralcomputation.uk/submission.h... Deadline: 12 May Please share All info: neuralcomputation.uk Sponsors: ARIA; Francis Crick Institute Organisers: @danakarca.bsky.social @neuralreckoning.bsky.social
- Reposted by Arnd RothAw, we got the cover for our new paper on X-ray imaging and atlas building in the snail brain. www.pnas.org/doi/10.1073/... Thanks @pnas.org .. and to @sussexneuro.bsky.social @leverhulme.bsky.social @ukri.org for funding support #invertebrate #brain #neuroscience THREAD: bsky.app/profile/kevi...
- Looking for a quick way to map the brain of your favourite small animal model? See our new paper. www.pnas.org/doi/10.1073/... 1/10
- Indeed €500 bn+. Klotzen, nicht kleckern.
- Reposted by Arnd RothReal question. What is an “illegal protest”? Real question. He was convicted of a crime. Why hasn’t he been expelled?
