Xantha Karp
C. elegans geneticist, how diapause affects development, microRNA, equity in STEM, professor at Central Michigan University, she/her/hers.
https://karplab.org
orcid.org/0000-0001-6602-5583
- Reposted by Xantha KarpBig Event Today MAHA INSTITUTE PRESENTS Reclaiming Science: The People's NIH with Dr. Jay Bhattacharya January 30, 2026 12:00–5:00pm Registration Starting at 11:00am The Willard Hotel The Crystal Room 1401 Pennsylvania Ave NW Washington, DC 20004 1/5
- Reposted by Xantha KarpI am pleased to share our latest paper on the role of the alternative polyadenylation factor CFIM-1 (NUDT21) in C. elegans germline development. academic.oup.com/genetics/adv...
- Reposted by Xantha KarpThe Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems academic.oup.com/genetics/adv...
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- Reposted by Xantha KarpFriends! I am so happy to share our new preprint! Hydrogen peroxide has been the most common reactive chemical threat to life forms since the Great Oxygenation Event 2.5 billion years ago. How do animals like C. elegans sense it fast and escape? www.biorxiv.org/content/10.6... Thread 1/
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- Reposted by Xantha KarpThe appropriations bill that includes NIH is being finalized. The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants. The House version does not and OMB has issued a veto threat if the House includes such language. 1/3

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- Reposted by Xantha KarpNow in print: tour de force mitonuclear epistasis study in C. elegans. Start to finish, vision and execution, 100% Tuc Nguyen @tuchmnguyen.bsky.social
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- Reposted by Xantha KarpI taught Genetics again this year. We need to include discussion of the problematic history of our field, especially as the claims of eugenics are once again centered in our political discourse. Last year I wrote this piece, explaining my reasoning and approach 🧪 1/n www.cell.com/trends/genet...
- Next week, we welcome @rebeccasear.bsky.social in our Lecture Series. Rebecca will talk about 21st century eugenics, scientific racism and the role of academia in promoting political ideology. Just register here to participate 👉 rotorub.wordpress.com/roto-lecture... #PhilSci #HPBio
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- Reposted by Xantha KarpRead this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
- Congratulations to Karp lab student Vusani Ntuli who won the Best Poster Award at the Central Michigan University Biology Undergraduate Research Symposium yesterday! I’m so proud of him and of the other 5 Karp lab presenters.
- Reposted by Xantha KarpSAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
- Reposted by Xantha KarpHappy International Day of LGBTQIA+ People In STEM! How are you celebrating it? #LGBTQSTEMDay #PrideInSTEM
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- Reposted by Xantha KarpMake males live more than 400% longer and prevent sexual disfunction late in life?! We're down with it. Our latest preprint: Disruption of the insulin signaling pathway in C. elegans dramatically increases male longevity and enhances reproductive health late in life. www.biorxiv.org/content/10.1...
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- Reposted by Xantha KarpNektarios Tavernarakis on why curiosity-driven research, not focusing on application, is fundamental to problem solving and requires government support in @emboreports.org doi.org/10.1038/s443...
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- Reposted by Xantha KarpFor what it’s worth, The Wyoming Worm lab has funding for 5 years along with exciting projects with solid foundations. We are is still looking for capable, dedicated, and fun-to-work-with lab members at all career stages. davidfay@uwyo.edu scholar.google.com/citations?us...
- Reposted by Xantha KarpAnd the next one: dx.doi.org/10.1038/s44318-025-00585-z . Super-fun collaboration with @partchlab.bsky.social & @gotworms.bsky.social to find similarities between developmental and circadian clocks – supported by @fmiscience.bsky.social Facilities and, financially, @snsf.ch and @erc.europa.eu . 1/n
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- Reposted by Xantha KarpWatch Lucas' amazing artistic/musical rendition of C. elegans larval development and our work on developmental timing and molting here youtu.be/-hGHYRvw87w and read on his inspiration and challenges below
- In May, Lucas Morales represented the FMI at the @eu-life.bsky.social Science Vision Talk Contest in Brno—Eurovision for science. His live talk had surprises, but he later recorded a new version. Watch it and read his Q&A on science, career and communication: www.fmi.ch/news-events/...
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- Reposted by Xantha KarpPaper alert! doi.org/10.1038/s443... - "A scheduler for rhythmic gene expression". We show how 9 txn factors suffice for rhythmic gene expression of thousands of genes with any phase or amplitude in #Celegans larvae (and also look at the tissues where oscillations happen) 1/n
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- Reposted by Xantha KarpI have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14
- Reposted by Xantha KarpHi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :) www.youtube.com/@Workingwith...
- Reposted by Xantha KarpIMO this hasn't gotten enough attention: a recent memo at NIH announces that peer review will be devalued in determining which grants get funded, granting more power to political appointees to make decisions based on the admin's whims over scientific merit kffhealthnews.org/news/article...
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