Sandhya Koushika
Cellular neurobiologist TIFR India who loves genetics, live imaging and worms. Science is fun, let's go exploring.
Sci comm, write bad poetry, 2 girl mom
lab: tinyurl.com/5n7s6ens
scholar.google.co.in/citations?user=c4zD…
- Tomorrow The Hindu will host a webinar titled, 'How we can bring our scientists back home', on January 31, 5:00 p.m. Registration FREE: ask ques & interact with panelists. 3 best questions will receive a free online subscription to @thehindu.com Register: www.thehindu.com/events-regis...
- Cool study & thread from @krishnanyamuna.bsky.social . pH maps inside organelles- take home its NOT uniform
- Fun hear.
- Important consideration when doing imaging
- Diving into the literature… I think it's the first time I see correlative live-cell/EM data after photobleaching - it shows how intense light can actually destroy microtubules rather than just bleach fluorescent tubulin along a neurite (from onlinelibrary.wiley.com/doi/10.1002/...)
- Wonderful initiative linking @biorxivpreprint.bsky.social to @qedscience.bsky.social. 👍🏽👏🏽 @odedrechavi.bsky.social & @richardsever.bsky.social
- Cool study
- An Asgard archaeon with internal membrane compartments biorxiv.org/content/10.1101/202…
- super interesting-dig in
- 🧵 I've been meaning to write a #Skytorial on our recently posted prepring in which we show evidence that the Golgi 🥞 is a mechanoresponsive organelle. Extracellular mechanical forces also tune Golgi export capacity! 👉 www.biorxiv.org/content/10.1...
- Spatial memory & motion are expressed simultaneously during behaviours. Synchronization of hippocampal dynamics (HD) occurs during movement. Disrupting HD during locomotion impairs memory. ⭐ work @rhythmicspikes.bsky.social @ncbsbangalore.bsky.social in #IAN25 Read more: tinyurl.com/4dah3xw6
- Super interesting-dig in Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance | Science www.science.org/doi/10.1126/...
- A 19-page article in the National Geographic that covers the work of @uramakri.bsky.social @ncbsbangalore.bsky.social @tifr.res.in on black tigers, mutation load and corridors for tiger migration. Important story and impactful work. 👏🏾 www.nationalgeographic.com/animals/arti...
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- What a feast....
- This award aims to highlight outstanding research by active neuroscientists working in countries underrepresented in neuroscience publications and conferences. @network-alba.bsky.social @sfn.org @ibroorg.bsky.social @fens.org
- Our worm lab is recovering from a mite attack. Trainees devoted hours to cleanup A mite or two or an army They are hateful and smarmy Our helpless little ones Crushed by their whirling carny Hello give up not Gather all the stock Pick, bleach, clean Burn to death a game well fought
- Really interesting preprint on how the nervous-system modulates heat-dependent fertility. Work from @ethanewe.bsky.social from @odedrechavi.bsky.social lab. May well be relevant in a planet that is heating up.
- Neuronal oversight of germline small RNAs prevents heat-induced sterility in lab-domesticated Caenorhabditis elegans biorxiv.org/content/10.1101/202…
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- Thank you--this is cool
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- How widespread is heat-dependent sterility. Is this only in C. elegans? Does it happen in other nematodes or other cold-blooded animals?
- 😮 Just WOW!! Spray GFP mRNAs on plant leaves and the leaves translate this and you get glowing leaves. www.biorxiv.org/content/10.1...
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- Loved this @heiman.bsky.social
- Read today "Comparison is the thief of Joy" True that
- Our dept @tifr.res.in ran an MSc by research for ~25yrs. Our last batch graduated this month. Several headed to excellent PhD programs, some to jobs. Congratulations and good luck for many fun adventures. 👏🏾Sohan Seal from my lab headed for a PhD to @mpi-cbg.de. 2nd from L, row 2
- 😔 Doing science has taken on elements of a corporation w/ writing=one "vertical". Output of research as patents and IP seems to be another. Metrics is a temple at which we worship at. Sometimes overlooked is serendipity, small groups that meander & in this context the idea that writing is thinking.
- Important.......
- "Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer" www.biorxiv.org/content/10.1...
- ⭐ 🌟 image
- Our July issue is here! rupress.org/jcb/issue/22... The cover shows a confocal timelapse imaging of #Celegans one-cell embryo expressing fluorescently labeled plasma membrane, microtubules, chromosomes, and ZEN-4, a plus-end directed kinesin motor protein. By Adhikary et al. doi.org/10.1083/jcb....
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- Worms with neurons, a bracelet? Promise to buy. Missing #Worm25
- Role of clathrin adaptor complex AP3 in secretion of dense core vesicles from the Sahu lab, NBRC. Badal from my lab has added an experiment testing the role of AP3 in secretion of neuropeptides in C. elegans.
- AP-3 complex sorts preferential cargo to govern dense core vesicle function in neuroendocrine cells biorxiv.org/content/10.1101/202…
- ❤️
- How can one not love the “Worm Community” !!! 🪱🪱👨🔬👩🔬🧑🔬👌🏼👌🏼 🫶🏼🫶🏼 #Worm25
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- Folks at #worm25 please post. For those of us who did not make it we have to experience it vicariously through your posts.
- 👌🏽
- Nobel winners of worms! Curiosity driven science is essential! @genetics-gsa.bsky.social
- Nice study
- This is cool. CryoEM showing COPI coat containing GOLPH3, together with functional data suggests the mechanism for cargo retention/transport. The mechanistic basis of cargo selection during Golgi maturation Taylor, Zubkov, Ciazynska et al. doi.org/10.1101/2025...
- Looking forward to working with @network-alba.bsky.social
- Congratulations to our newly elected Board members: 🎉 Sandhya Koushika, Jatin Nagpal, and Ibukun Akinrinade 🎉 Chair-Elect: Bita Moghaddam Thank you to everyone who joined the ALBA General Assembly 2025! 💙 We’re grateful for your energy and insights. @fens.org
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- 😍
- This was a brilliant public talk @tifr.res.in by Nobel laureate Prof. Brian Schmidt. It was informative, simple to understand for people outside the field, funny & inspiring. You can watch a recording here. youtube.com/watch?v=awik...
- From the Big Bang to black holes and dark energy—discover the epic story of our Universe with Nobel laureate Prof. Brian Schmidt! 🗓 June 5, 2025 | 🕔 5 PM 📍 Homi Bhabha Auditorium, TIFR, Mumbai Free & open to all (Photo ID required) #TIFRScience #PublicLecture #ScienceForAll
- Based in Mumbai? Interested in general in science. Come to the lovely @tifr.res.in campus to listen to Paul Nurse. TODAY........
- What is life? Find out from Nobel laureate Paul Nurse as he explores 5 big ideas in biology! Join us for a public lecture at the Homi Bhabha Auditorium on May 30, 2025 (Friday). Open to all (photo ID required) #TIFRScience #PublicLecture #ScienceForAll #NobelLaureate
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- Not just the publishing system but the reward rubric where each authors contribution in an multi-author paper is examined. Additional aspect compared to a few decades ago, long papers have become the norm. Reviewers expect a more 'complete story' w/ several complementary approaches, so more authors.
- Looking forward to this fun meeting
- Learn about the #cytoskeleton: From #evolution to #biophysics and more at EMBO Workshop "Frontiers in Cytoskeleton Research" in Pune, India, 3–7 Nov Abstract submission deadline: 20 Jun Registration deadline: 15 Jul buff.ly/b7zAyw8 #EMBOcytoskeleton #StructuralBiology #CellBiology #EMBOevents 🧪
- "I was starting to think that these worms have a way of bringing out the best in humans—generosity, cooperation, and an unbridled curiosity about life." TRUE THAT
- It was so much fun to discuss why we do basic science. "If we understand how biology works, then lots of useful applications will come out of it ... But honestly, that’s not the only thing that drives people. People are just curious, and they want to know how living systems work." #Celegans 🧪🧬🪱
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- 😅. These are much nicer non-pathogenic, free living worms 😉
- A 🧵 to walk those interested through this paper...
- Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening www.cell.com/cell/fulltex...
- What a cool finding!
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- 👍🏾
- WOW!! Poems show a 65% ⬇️ in ranges of porpoise. “We used the occurrence sites in poems to map the historical distribution of the Yangtze finless porpoise. The number of grids with occurrences declined from 169 in the Tang Dynasty to just 59 in modern times.." www.cell.com/current-biol...
- Biodiversity research and likely conservation efforts likely benefits from the combination of art and science as presented in this study.
- Interesting study and lovely movies from @lllackner.bsky.social lab
- Jason Casler @jasoncasler.bsky.social, Clare Harper and Laura Lackner @lllackner.bsky.social find that mitochondria–plasma membrane contact sites regulate the ER–mitochondria encounter structure. journals.biologists.com/jcs/article/... #JCSMitoSI #OpenAccess #ReadandPublish
- More functions for the LITE-1, a suggested UV light activated ion channel, making it a multimodal sensor
- The C. elegans gustatory receptor homolog LITE-1 is a chemoreceptor required for diacetyl avoidance biorxiv.org/content/10.1101/202…
- A fun study. Salt stress sensed by a pharyngeal neuron (acting much like a sensory neuron) using GLR-9 an ionotropic receptor. Dig in
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- Continuing the theme, consider this one too.
- Interesting....
- Being passively touched and actively touching something have different ethological meanings. @grohlex.bsky.social &co show that active & passive #touch are represented differently in the brain; the higher-order #thalamus differentiates active & passive touch @plosbiology.org 🧪 plos.io/44pswmm
- Useful review. Anemia is an important public health issue for women's health in India
- Most viewed in the last 7 days from JAMA: Review focuses on the screening, diagnosis, and treatment of absolute iron deficiency with or without anemia. ja.ma/42irqpQ
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[This user deactivated their account]- Yes he did.
