Stuart Oldham
Post-doc at the Murdoch Children's Research Institute.
I am interested in brain development, neural connectivity, and spending too much time creating PowerPoints.
- My very normal, by the book presentation from this years OHBM is now available. So if you weren't at OHBM, were there but happened to miss it, or if you did see it and just want to relive it all over again, here is your chance :) I'm quite fond of this one. www.youtube.com/watch?v=lP86...
- Very normal. Totally normal. 😉
- Very normal, very serious
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- Any "scientific" figure is made in MATLAB. For some animations (i.e., anything happening on the surface of the brain) I am just saving each frame as an image then combining into a video seperately and embedding that in the PowerPoint. Otherwise, everything else is made in PowerPoint :)
- In case anyone is interested, I've put that animation I made of brain development from 21-40 weeks GA on YouTube for your enjoyment/reference🤰👶🧠 Now you don't need to go to that other place anymore to find it 😁 youtu.be/C20GQ5CtVt0 Plus the code is now up! github.com/StuartJO/Fet...
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- Yessss, one of us, one of us #PowerPointGang
- This is my favourite YouTube video of all time, and since today marks three years since its release, I thought I’d share it. It’s a brilliant example of edutainment, and has inspired my own talks. We scientists could learn a lot about presenting in a fun and engaging way! youtu.be/yUaNHA-WQWg?...
- Second poster on today + talk tomorrow!
- On Friday/Saturday I have a poster (1205) on our work using generative network models, where I explore how heterochronous spatial gradients constrain brain connectivty 🧠⌛🏳️🌈 Also Saturday (11:30am; Great Hall) I have a talk on this work, so make sure you have recovered from club night in time for it!
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- I think they were recorded this year by OHBM? So it might be available soon (don’t quote me on this haha)…
- For those at OHBM, check out my posters and talk! Today and tomorrow I (and maybe @garedaba.bsky.social) will be presenting my poster (1012) on our work linking fetal gene expression to neonatal connectome organisation 🧬🧠👶🌐 1/2 #OHBM #OHBM2025 (preprint here www.biorxiv.org/content/10.1... )
- On Friday/Saturday I have a poster (1205) on our work using generative network models, where I explore how heterochronous spatial gradients constrain brain connectivty 🧠⌛🏳️🌈 Also Saturday (11:30am; Great Hall) I have a talk on this work, so make sure you have recovered from club night in time for it!
- Do you like brain network hubs?🧠🌐✳️Do you like genes?🧬What about neurodevelopment?👶What if I told you the latest work by @garedaba.bsky.social and myself combined all of these?🤯🤯🤯 See Gareth's thread for a primer of our findings, then read the paper for the details! www.biorxiv.org/content/10.1...
- 🎨🧑🎨 Looking for a tool to visualize subcortical/thalamic data in 2D? Check out this python-based package I put together (subcortex-visualization on PyPI), plus a guide for creating your own custom atlas meshes and vector graphics! All feedback/tips welcome 😊 anniegbryant.github.io/subcortex_vi...
- What an amazing tool! 😍
- New computational neuroscience postdoc position with some great people doing great science at Monash University! careers.pageuppeople.com/513/cw/en/jo...
- It's the most wonderful time of the year With the deadlines compelling And everyone yelling, “It’s too long, I fear!” It's the most wonderful time of the year @ohbmofficial.bsky.social
- Four years to the day since I submitted my PhD thesis! It is also four years since I planned, shot, and edited this video the day before I submitted my PhD thesis... youtu.be/xalcIXR6zWA
- Some new work from myself, @alexfornito.bsky.social, and @garedaba.bsky.social where we investigate the performance of generative Network Models (GNMs) 🧠🌐🤖. A 🧵 (1/6) www.biorxiv.org/content/10.1...
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View full threadSo where does this work leave GNMs? In fairness, they were originally designed to capture topology, not topography. We wanted to push the models to their limit to identify where they can be improved (5/6)
- As the brain's spatial embedding is a key aspect of its organisation and function, we believe GNMs should aim to capture this going forward. Features like heterochronicity may improve GNMs ability in this regard. Check out more of our ideas in the paper! 😊 (6/6) www.biorxiv.org/content/10.1...
- We find this is because GNMs cannot accurately capture long-range connections, these connections are needed to define the precise topography we observe in the empirical data (3/6)
- In addition, we show how a common way of evaluating GNMs is very sensitive to differences in short-range, but not long-range, connections. This has implications for how to select best-fitting models (4/6)
- GNMs create synthetic networks based on mechanisms/constraints that are believed to shape brain networks. The resulting networks replicate topological properties of real brain networks, but not topographical properties (i.e., spatial embedding of topology) (2/6)
- If you like: - brain development 🧠 - cool uses of machine learning 🤖 - genes 🧬 - pretty figures 🖼️ - open access data 🔓📊 check out the latest by @garedaba.bsky.social, a 3D cellular-resolution digital atlas of the fetal brain with corresponding gene expression data! www.biorxiv.org/content/10.1...
- I have achieved the impossible, I submitted my OHBM2024 abstract more than 24 hours before the final deadline. I hear they are going to build a statue in my honour
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- Only if I get a second statue
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- One day others will see the light!
- Hello Bluesky/Twitter refugees! For my first post, I invite you to check out the latest work by @garedaba.bsky.social and myself where we look at thalamocortical gradients in human and mouse brains 🌈🧠🐭🌈 In short, we highlight evidence for a supra-nuclear axis of thalamocortical organisation
