Mac Shine
Computational Neurobiologist from Sydney, Australia. https://shine-lab.org. Banner image from https://www.gregadunn.com.
- Reposted by Mac ShineI recently had the pleasure of chatting with @macshine.bsky.social as part of the OHBM Award Winner interview series; thanks for a great conversation! 🙏 Catch the interview here 👇
- Each year we have the pleasure of interviewing the OHBM Award Winners 🏆 First up is Prof Mac Shine, winner of the 2025 Early Career Investigator Award! 🌟 @macshine.bsky.social Watch the interview here: www.ohbm-com.com/blog/intervi...
- Reposted by Mac Shine𝗔 𝗡𝗘𝗨𝗥𝗢𝗘𝗖𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗣𝗘𝗥𝗦𝗣𝗘𝗖𝗧𝗜𝗩𝗘 𝗢𝗡 𝗧𝗛𝗘 𝗣𝗥𝗘𝗙𝗥𝗢𝗡𝗧𝗔𝗟 𝗖𝗢𝗥𝗧𝗘𝗫 By Mars and Passingham "Understanding anthropoid foraging challenges may thus contribute to our understanding of human cognition" Going to the top of the reading list! doi.org/10.1016/j.ne... #neuroskyence
- random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social
- Reposted by Mac Shine*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11
- Reposted by Mac ShineWhat changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains? Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales. braininspired.co/podcast/220/
- Reposted by Mac ShineExcited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social! We asked: How does the motor cortex account for arm posture when generating movement? Paper 👉 www.biorxiv.org/content/10.1... 1/10
- Reposted by Mac ShineAdaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
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- Reposted by Mac ShineTheoretical neuroscience has room to grow — a Comment article by Ann Kennedy @antihebbiann.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...
- I need some help from the #neuroskyence Bluesky-verse. Anyone know the source of this ~quote from Walter J. Freeman Jr.: "the secrets of the brain are hidden by two of God’s own firewalls: neurobiology and non-linear dynamics". I read it yrs ago but can't seem to find my way back to the source.
- Reposted by Mac Shine🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...
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- Reposted by Mac ShinePrefrontal axons going to lots of places! doi.org/10.1016/j.ce... #neuroskyence
- Reposted by Mac ShinePairs well with www.nature.com/articles/s41... “Our results indicate that individual V1 neurons do not signal how the actual visual input deviates from the animal’s predictions, as postulated within the predictive coding framework” Thrilling to see a major theory get tested!
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- Reposted by Mac ShineExciting new preprint from the lab: “Adopting a human developmental visual diet yields robust, shape-based AI vision”. A most wonderful case where brain inspiration massively improved AI solutions. Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy arxiv.org/abs/2507.03168
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- Reposted by Mac ShineAttractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...
- Reposted by Mac ShineHow does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...
- Reposted by Mac ShineShort new piece on aphantasia just out in TiCS: www.sciencedirect.com/science/arti... Key idea: aphantasia often involves a lack of *visual-object* imagery (explaining subjective reports & objective correlates) but selectively spared *spatial* imagery (explaining preserved task performance).
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- Another great article from @thetransmitter.bsky.social and Laura Lewis, who has been working painstakingly over the last few years to help ramp up the spatiotemporal resolution of fMRI so that we can really start to dig into whole-brain signals in vivo.
- ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis. www.thetransmitter.org/human-neurot...
- Reposted by Mac ShineICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis. www.thetransmitter.org/human-neurot...
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- Reposted by Mac ShineNew preprint! Why are long-range connectomic interactions in the cortex dominant in shaping dynamics in some experiments but apparently negligible in others? We (w/ R Maran, @elimuller.bsky.social) address this question by studying a new hybrid model of cortical dynamics. arxiv.org/abs/2506.19800
- Reposted by Mac ShineThe Open Science Room has been an exciting space at the OHBM Meeting for many years, but its future is threatened. Please sign this petition to signal your support for preserving a dedicated space for the OSR at future meetings. ohbm.github.io/osr2025/peti...
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- Fantastic article from one of the leaders of the burgeoning field or layer-resolved functional MRI. A pleasure to read!
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- Reposted by Mac Shine🧠 The State of the Brain Special Issue features insights from last year’s keynotes, award winners & committee leaders. 🔗 Explore major findings & themes from 2024: apertureneuro.org/issue/12560 @arokem.org @alexfornito.bsky.social @macshine.bsky.social @vcalhoun.bsky.social @misicbata.bsky.social
- Reposted by Mac ShineNew preprint modelling suppression depth in binocular rivalry and continuous flash suppression with Hugh Wilson, @macshine.bsky.social, & David Alais
- A Minimal Physiological Model of Perceptual Suppression and Breakthrough in Visual Rivalry biorxiv.org/content/10.1101/202…
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- Reposted by Mac ShineWhen I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
- Hard agree. Great article on a timely issue by @neuralreckoning.bsky.social for @thetransmitter.bsky.social
- Large-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration, writes @neuralreckoning.bsky.social. #neuroskyence www.thetransmitter.org/funding/neur...
- Reposted by Mac ShineLarge-scale projects run the risk of stifling scientific independence. Instead, let’s explore alternative mechanisms of collaboration, writes @neuralreckoning.bsky.social. #neuroskyence www.thetransmitter.org/funding/neur...
- Reposted by Mac ShineTogether with @macshine.bsky.social & @elimuller.bsky.social we have a cool interdisciplinary project on compositional cognition, and we’re looking for a PhD student. More details here www.findaphd.com/phds/project... DM or email any questions Please RT or pass on to interested students. Thanks!
- Reposted by Mac ShineThis is phenomenal. Sea surface temperatures are >5C above average to the west of the UK and around Iceland. It's the strongest area of anomalous warmth on the planet at the moment. It's the warmest in recorded history for northwest Europe.
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- Reposted by Mac ShineApplications are now open for our fall internship program! This is an excellent opportunity for a beginning science journalist to report and write about the fast-moving field of neuroscience. Apply now: simonsfoundation.wd1.myworkdayjobs.com/en-US/simons...
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- Reposted by Mac ShineOHBM Lunch with Mentors will be happening in Brisbane! Fill out the registration form below to enter a lottery draw. Registration closes May 25th 12pm AEST. Register here: docs.google.com/forms/d/1vuF... Information on this year's Mentors is available here: www.ohbmtrainees.com/lunch-with-m...
- Reposted by Mac ShineBetter Code, Better Science - Introducing a new open-source book project on scientific coding using AI tools russpoldrack.substack.com/p/better-cod...