Bahaar
PhD in genetics using C. elegans #teamworm | She/Her/Hers | chromatin, condensin, gene regulation, teaching, advocacy
- So I started watching the extended editions of #lotr to do attempt the “so it begins” at midnight, but I needed to take a break to complain about #RingsofPower
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View full threadShe also would’ve been great a for that weird romance thing they wanted with Sauron, since her name literally means “Silver Queen” It also would’ve been awesome bc they could contrast it with her actual romance with Elrond, the elf she hasn’t yet married!
- Again, it just makes me so mad bc there’s so much lore to use and they went for lazy but ended up being cursed “recognition“ bc they had to get different actors anyway What was the point? Other than a soulless cash grab 👀
- Watching this makes me wonder why, if they desperately needed a female protagonist, didn’t they write her as Celebrian?! You know, daughter of Galadriel and Celeborn?! There’s a canon character for them to use
- Celebrian would’ve been perfect too bc she’s born after the First Age, so they could’ve written her to be curious and rebellious bc she was born in “peace”, that she didn’t understand why her mother won’t look for her father,
- Like I’m mind blown at just how young Elijah Wood was in these fills but carried that emotional weight on his shoulders
- And we know why Amazon chose to use Galadriel for #RingsofPower 🙄 they wanted a recognizable character even though they literally had the recognizable IP!
- You see, #lotr is a really vast world and one thing Peter Jackson did was to make sure he chose a good protagonist in both Frodo and Aragorn
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- Also ngl but I’d rather get a drink or meal voucher instead of sitting in recycled air for longer 👀
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- Oh yeah, forgot to mention 😭 Worms have holocentric chromosomes, so they have to do meiosis with adjustments 😅
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- I swear there's a bunch of loop-extrusion model papers that I can't remember right now But I know that in worms, Cohesin is only lost from the crossover during meiosis I but stays holding the sister chromatids together for the rest of bivalent – argument for around?
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- Choose something unhinged 🤷♀️ I chose the absurd cover and title on this romantasy that I knew was gonna be cringey and it’s fantastic for processing images
- Apparently the only difference between brassiere and brasserie is where the “i” goes 🙃 Good thing I learned the difference before I walked into this place 🤡
- Thank you to all the animals that support biological research 💕 here’s a tribute to our Sentinal who ensured the safety of our colony #compassionawareness #cultureofcare #umich #zebrafish
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- Congratulations!
- And not just any Kleenex, it had to be the lotion ones
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- That’s why you’re supposed to go the weekdays 😭 less food samples to tempt you
- This is poetry 🫡
- Katy Perry “couldn’t recommend this experience more,” which is useful information for those deciding between space travel and booking a basic economy ticket on Spirit that doesn’t let you carry on any luggage so you have to wear 13 layers of clothing onto your flight pitchfork.com/thepitch/kat...
- This was wild 😅
- Um can someone answer if these #tariffs are going to affect the price of chocolate? For science?😬
- Stanley Tucci‘s dinner party show is really good and relaxing to watch while cooking Also the inclusion of scientists is 🙌🎉🍻 I kinda wanna host a dinner party now 🥺
- Ours was March 17 (last page in my lab notebook bc I dated everyday) I was teaching an animal physiology lab class. It was spring break and we were told that the students aren’t coming back So the prof emailed us and we recorded videos of the mice for the students to do the “endotherm lab”
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- I think we did a mix of recordings and data from previous semesters that students had to analyze for the lab course For the lecture, the professors recorded lectures and then held hybrid “problem solving” sessions where I was moderating the chat to answer questions as they came in 😅 it was intense
- I look back and realize how much of my life was impacted by that time I got into #skypeAscientist bc I wanted to combat stereotypes against scientists being perpetuated by anti-science and anti-vaxxers. I didn’t want ppl to refuse life-saving interventions like vaccines
- It also sparked my interest in #sciencepolicy, institutional operations, and the entire research enterprise I wouldn’t be in the role I’m currently in without what happened at that time
- We were required to mask and get our temperature taken before going into the building There was also a COVID surveillance testing program to get weekly pcr testing I was so happy when they switched from swabs to saliva bc I got tested weekly
- There was also a grad student strike in the fall (I almost forgot 😅) Against the decision to bring undergrads back to campus without any good plans for containing spread I was 1/5 striking grad students in my department (we had a lot of international students who couldn’t risk it)
- In the fall, I taught intro bio lecture, completely remote. Half of my goal was to create a 1.5 hour class where my students didn’t feel like they were just staring at their screens. I used memes, stories, jokes. I asked them silly questions instead of attendance
- At the same time, I was doing my thesis work but we were restricted by shift work Only so many ppl were allowed in the lab at one time. I had morning shift (8am - 2pm). Some days, that was only enough to do half of my genotyping (dna isolation, pcr). I’d have to run the gel the next day
- I think I ended up having office hours whenever it worked bc I had students in multiple time zones In summer, I helped rewrite the lab manual for the fall term ➡️ social distancing, only 5 students in class each week. So we created a rotating set of 3 weeks that students could complete per “unit”
- Exactly The entire point of #Project2025 is to enrich a select few at the expense of us and whatever generations exist to inherit after us
- I have a naive question: why do governors and senators of other states send campaign fundraising texts to me? If I’m not even donating to my state candidates, why would I be donating to you?
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- My friend said this to me yesterday 🙃 she said “I can’t even decide if I should do this experiment, what’s the point when I’m entering a job market that’s gonna saturated by ppl from the federal service with way more experience than me”
- Every one of my friends is asking “do I even have a career going forward”
- AI searches with no context 🤦♀️
- I got asked the most unbelievable thing this week: “Do geneticists still use the human genome of the executed convict many years ago?” HELLO?! WHAT?! Is this the newest urban legend for the kids?
- I told them NO (I wanted to say fuck no) and then went into a whole thing about the human genome project being volunteers that was aggregated, and also about ethics in research, the National research act of 1974, how prisoners are vulnerable populations and we apply extra protections to them
- But this was wild and it wasn’t just asked once Multiple kids asked this and I need to know where this is coming from bc wtf
- Also, you don’t get a lump sum to spend indiscriminately The researcher spends a line of credit and submits invoices to the NIH, who then will decide if those are APPROPRIATE before reimbursing the researcher Ask any researcher about their RPPR which is required to continue receiving funds
- One of the remarkable things about #NIH is how rigorously its grants, research, and employees are reviewed. NIH science and scientists are held to a high standard by external reviewers — via study sections and councils, or BSC/site visit reviewers. And the reviews have teeth. 🧪
- When I call my representative, I usually talk about cancer, Parkinson’s, Alzheimer’s, and miscarriage. Almost every person I’ve run into has a loved one who has experienced one of these, and they can’t say they don’t want cures/preventions
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- That’s a waste of maple syrup Use high fructose corn syrup!
- 🙃 Elon tweeting about how SpaceX engineers can help
- I have to book flights for a conference and I’m terrified It doesn’t help that I have no idea on how to talk about this anxiety at work
- Literally the most amazing thing reported: a study on women who got vaccinated against HPV before age 14 found that there’s 0% — ZERO incidence of cervical cancer in said women as they’ve entered their 30s and beyond And RFK opposes that to make money while preventing ppl from getting it? 👟
- This is how they fucking bankrupted Red Lobster 🙃
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- Thank you! 🥺
- Dosage compensation in worms is a paradigm for chromosome-wide gene regulation by a condensin as C. elegans don't completely shut down one X like mammals. Instead, each X is downregulated to have 1/2 expression by condensin I-DC and together both X's = single male X.
- By demonstrating that condensin I-DC has an active ATPase that's required for dosage compensation, we hopefully apply these findings to other scenarios where condensins mediate gene regulation #condensin #generegulation #chromatin #celegans 🪱
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- We also found that loss of this function can prevent condensin I-DC from strongly binding DNA but it is random, leaving 2 populations – strongly DNA bound and weakly DNA bound, contributing to the lack of dosage compensation and maternal effect lethality in offspring
