SmithLabUMBC
We are a diverse group of chemists and biochemists studying the structure-function relationship of metalloproteins 🏳️🌈🧪🧬
Find us here: t.co/eHC3pQp4dz
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- Reposted by SmithLabUMBCA quorum-sensing molecule from Pseudomonas aeruginosa induces defensive multicellularity in a coinfecting pathogen -in PNAS from @anukharelab.bsky.social www.pnas.org/doi/10.1073/...
- Reposted by SmithLabUMBCLots of PhD opportunities for UK + international students involving my lab. Topics relate to metals & microbiology. First up: TonB-dependent receptors in commensal Neisseria in my lab at Durham, with @kjosts.bsky.social and @mattbashton.bsky.social. www.findaphd.com/phds/project...
- Come be our colleague--we're hiring! We have an opening for TT Asst. Prof. in Physical Chemistry in the Dept. of Chemistry and Biochemistry. Interests in spectroscopy, optics, or biophysics broadly defined! I know we're late to the game, but see our add here: apply.interfolio.com/180223 Please RT!
- Reposted by SmithLabUMBCThis is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again. www.nature.com/immersive/d4...
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- Reposted by SmithLabUMBCBeen hearing some horrifying chatter about dealing with the new #NIH common form and #ScienCV system, so I put together a short video with some tricks for mitigating some of those pain points. Hope it helps? 🧪 open.substack.com/pub/emptymod...
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- Da Bears!!!!! 🐻
- It's the best day of the year: lab clean-up day! What will we find this year?! 😁🫠😱
- Reposted by SmithLabUMBCIs your New Year's resolution to unveil structural details for your biological macromolecule? Reserve a spot in our January protein crystallization run before Friday! Package Acceptance & Plate Setup: Tues Jan 12th – Thurs Jan 15th Tues Jan 20th – Thurs Jan 22nd
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- Reposted by SmithLabUMBCIs arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines. www.biorxiv.org/content/10.6...
- Reposted by SmithLabUMBC🚨Excellent editorial in ACS Central Sci 📣 Thank you @carolynbertozzi.bskyverified.social for your support and to @louisflwilson.bsky.social for spotting these mistakes + drafting an excellent manuscript #CryoEM #StructuralBiology #vidalized ACS Central Science pubs.acs.org/doi/full/10....
- Reposted by SmithLabUMBCGreetings! I decided to make a YouTube video of my AlphaFold workshop that I've given a few times in the past year. Caveats aside, people seem to find this useful for thinking about how to model protein interactions and how to interpret various AF outputs 1/2 www.youtube.com/watch?v=u63o...
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- Time to celebrate the graduates!
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- Congratulations to the newest PhD from the lab!!
- Looking forward to @hhmi-science.bsky.social Gilliam Fellow Alexander Paredes' Ph.D. thesis defense today at 11 am in Meyerhoff Chemistry and Biochemistry seminar room 120! Don't miss it!!
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- Was feeling really good about a manuscript in review until receiving feedback from a **single** reviewer that was **1461 words long** and asked for a solid R01's-worth of work for a single manuscript revision. Sigh.
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- Pleased to be hosting @jeffmugridge.bsky.social here at @umbc.bsky.social Chemistry & Biochemistry! Look out for his great talk today from 12 - 1 pm in Meyerhoff 120 entitled: "Metals, mechanisms, and messages: how metalloenzymes do chemistry on RNA to control gene expression" 🧪🧬⚛️
- 🚨Just in press @asbmb.bsky.social JBC!🚨 Alex & Chioma's paper detailing the interaction of Fe(II) with an intact membrane His kinase for the first time! Binding stoichiometry ✅ Fe(II) structure ✅ Direct observation of selectivity ✅ Signal transmission pathway ✅ Read more here: tinyurl.com/49wdkecu
- Reposted by SmithLabUMBCThe National Crystallization Center is hiring for two positions: a research scientist position focused on progressing our crystallization optimization projects, and a research support specialist to support operations of the Crystallization Center!
- What another fantastic biomolecules costume night in CHEM 437!! 🎃 🧪 🧬
- Chemistry pumpkins 2025! The periodic table o' pumpkins continues to grow!
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- Reposted by SmithLabUMBC🚨Our paper is out! 🥳 Hijacking a bacterial ABC transporter for efficient genetic code expansion. Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social www.nature.com/articles/s41... it all started years ago with a failed experiment 🧵👇 1/9
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- Hey, that's us! 😀
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- 🚨 Just out in @biorxivpreprint.bsky.social 🚨 Kate, Candice, and Mark's paper on the structure of the V. cholerae NFeoB NTPase catalytic cycle. Serendipity of a P1 spacegroup with 4 mols in the ASU played a role in capturing all the states, and Mg is pivotal! Read the paper here: tinyurl.com/263u9vtn
- A great opportunity to work with a great mentor!
- Someone got pooped from helping us decorate for Halloween…🎃
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- Reposted by SmithLabUMBCThe NSF GRFP is now limited to undergrads and first-year grads drugmonkey.wordpress.com/2025/09/26/t...
- Reposted by SmithLabUMBCThis may be the most important paper ever published about NIH funded research. www.science.org/doi/10.1126/...
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- Cool story on the re-purposing of a protein I worked on in graduate school! Curious about other work that led to this? See: tinyurl.com/56mybjmd tinyurl.com/ksmau4xm tinyurl.com/yw9av9yh tinyurl.com/yuujhajc tinyurl.com/5987f53r Way to go Burstyn Group alumni!! And check out: tinyurl.com/mvvpzj3f
- Pyrite would obviously win if it were there; however, in its absence, it's got to be either hematite or azurite...
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- Alright folks, first day of Biochemistry 1 for the Fall 2025 semester at UMBC. Let's go!! 😀🧬🧪🔬
- Reposted by SmithLabUMBCHere is the video from the Clinical Center patient in a different format. Thanks for @carolynyjohnson.bsky.social for covering this story.
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- Congrats to the newly-minted Ph.D. from the @smithlabumbc.bsky.social Dr. Misti Cartwright @chemisti.bsky.social ! Way to go on an excellent thesis defense!!
- Looking forward to @chemisti.bsky.social 's Ph.D. thesis defense today at 10 am in Meyerhoff Chemistry and Biochemistry seminar room 120! Don't miss it!!
- But...why...?
- Because making funding announcements harder to find is "efficient". smh. grants.nih.gov/grants/guide...
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- Way to go!!
- Reposted by SmithLabUMBCWell, this is a huge Executive Order power grab... www.whitehouse.gov/presidential... 1/3
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