Renee Chang

• Reposted by Renee Chang
  
  Kranzusch Lab kranzuschlab.bsky.social · Aug 22, 2025
  The beautiful, ever-expanding universe of viral proteins targeting nucleotide immune signals! Paper by @reneechang.bsky.social in @cp-molcell.bsky.social on a nucleotide sponge www.cell.com/molecular-ce... and preprint by @doudna-lab.bsky.social on viral nucleases www.biorxiv.org/content/10.1...
  

  A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense

  Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...

  cell.com
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