Study of 156 dengue patients shows distinct complement signatures by disease severity, with soluble CR1 emerging as an independent early predictor of severe outcomes.
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Aberrant systemic acute-phase complement responses in conjunction with soluble CR1 attribute to varying grades of dengue disease severity - PubMed
Our findings show that aberrant complement activation and levels of sCR1 could attribute to varying grades of dengue severity. Given its inverse association, the levels of sCR1 could likely render…