Patricia Gerdes
MSCA Fellow at Lund University 🇪🇺 🇸🇪 | Molecular Neurogenetics lab | retrotransposons, genetics, epigenetics, evolution 🧬 🧠 🐒
- Reposted by Patricia GerdesNew preprint from the lab! We dig into the regulatory roles of TEs in the mouse placenta, with some surprising findings. Led by the awesome @smamante.bsky.social. Particular kudos to him for navigating the many twists and turns of the project.
- Reposted by Patricia GerdesThe speed at which Oxford Nanopore is cancelling support for their devices is just mind boggling 😳 P2 solo will be decommissioned soon!!! This is not sustainable! @nanoporetech.com
- Reposted by Patricia GerdesSad to hear that Oxford Nanopore wants to discontinue the P2Solo later this year in favor of the P2i (the very pricey P2Solo that comes with a GPU to do the basecalling in it) It feels like such a big step in the wrong direction. They are a great sequencing company, not a great GPU upseller...
- Reposted by Patricia GerdesNew Year, New Paper!🎊 Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system www.biorxiv.org/content/10.6... Centerpiece of Jason Chobirko's PhD, talented PhD student co-mentored by Andrew Grimson & me. Really excited about it!🧵
- Reposted by Patricia GerdesWe are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...
- Very happy that this part of my postdoc work is now out as a preprint!! Our findings reveal a new mechanism by which retroviral pandemics may have shaped primate brain evolution 🧬🐒🧠 This was a true team effort! w/ @ofeliakarlsson.bsky.social @raquelgarza.bsky.social @jakobssonlab.bsky.social #TEsky
- New preprint from our lab: ‘Retroviral insertions contributed to the divergence of human and chimpanzee brains’. Very proud of this piece which took almost a decade to finish. www.biorxiv.org/content/10.6...
- Reposted by Patricia GerdesHow do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...
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- Reposted by Patricia GerdesNew paper from our lab! We found that LINE-1 transposons contribute to early human brain development. Funded by @asapresearch.parkinsonsroadmap.org www.cell.com/cell-genomic...
- Reposted by Patricia GerdesVery happy to share our protocols paper for CELLO-seq. This will make single cell long read RNA-seq more accessible and provides analysis guidelines. We hope this helps the #transposon #TEsky community and folks working on #singleCell isoform and allelic #gene expression. doi.org/10.1038/s415...
- Reposted by Patricia GerdesIs the annotation of viruses in the human genome accurate? We think not. Take a look at our new paper and let us know if you agree! www.science.org/doi/10.1126/...
- Reposted by Patricia GerdesCome to Lund! We are looking for a postdoc to join the team. #transposons #epigenetics
- Reposted by Patricia GerdesJoin our team as a postdoc and explore the exciting world of transposable elements and developmental biology with us! @imbavienna.bsky.social @vbcscitraining.bsky.social
- Reposted by Patricia GerdesNew preprint from our lab! Why is not everyone working on Transposons? Loss of H3K9me3 maintenance in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons www.biorxiv.org/content/10.1...
- Another successful year with our workshop at #UniStemDay2025. We explained to high school students how we study human brain evolution using human and monkey brain organoids and looking at gene expression 🧠🐒🔬🧬 w/ @vivienhorvath.bsky.social @ofeliakarlsson.bsky.social @lundstem.bsky.social
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- Reposted by Patricia GerdesWe are hiring! 3-year BBSRC-funded postdoc position available. TEs, epigenetics, pregnancy: if you love one or more of these keywords, apply through the link below. Please spread the word.
- Reposted by Patricia GerdesWe profiled the effects of our CRISPRi system targeting young L1 elements in human pluripotency & brain development. These elements deeply impact our transcriptome, but also have very distinct effects on their nearby genome. Check it out!! 🧬👾 #TEsky #CRISPR #L1 #development #epigenetics
- 🚨 New pre-print from Team Jakobsson! LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development. This work was led by @anitaada.bsky.social, @raquelgarza.bsky.social and @jakobssonlab.bsky.social from the Jakobsson Lab. www.biorxiv.org/content/10.1...
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- Reposted by Patricia Gerdes🚨 New pre-print from Team Jakobsson! LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development. This work was led by @anitaada.bsky.social, @raquelgarza.bsky.social and @jakobssonlab.bsky.social from the Jakobsson Lab. www.biorxiv.org/content/10.1...
- Reposted by Patricia GerdesNew preprint from our lab. Led by the outstanding @anitaada.bsky.social and @raquelgarza.bsky.social. Funded by @asapresearch.bsky.social and @vetenskapsradet.bsky.social. LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development www.biorxiv.org/content/10.1...
- Reposted by Patricia GerdesDon't miss the first CSH Asia meeting on transposons in April in Suzhou, China. Truly fantastic line-up! Abstract deadline at the end of the month... (why is not everyone working on transposons?).
- Reposted by Patricia GerdesWe're thrilled to announce that our project has been funded by @asapresearch.bsky.social in partnership with the Michael J. Fox Foundation! 🚀 Excited to continue exploring the role of transposable elements in Parkinson’s disease. Learn more here: www.lunduniversity.lu.se/article/52-m...
- Fantastic line up of speakers at the 7th Max Planck Freiburg Epigenetics Meeting! Looking forward to hear about all the interesting science done in the epigenetics field!! 🧬🤓 @mpi-ie.bsky.social
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- Reposted by Patricia Gerdes🧬 🧠 Excited to see it printed! We bring key insights on the epigenetic regulation of SVAs, including SVA-XDP: a polymorphic SVA driving a rare neurodegenerative disorder @jakobssonlab.bsky.social @vivienhorvath.bsky.social #TEworldwide #Transposons #XDP #NSMB + the volume has the cutest cover 🦔
- Reposted by Patricia GerdesIf you like #Transposons 👾 check out this feed and tag your posts with #TEsky! Thanks @tobybarilbio.bsky.social 🤗 bsky.app/profile/did:...
- Reposted by Patricia GerdesThrilled to announce that the EMBO workshop «Mobile Genome» will be back in Heidelberg, Nov 4-7th 2025 @EMBLEvents @EMBO. Registration open soon but you can already register interest. Organized with fantastic colleagues @juliusbrennecke @GonzalezLab_BCN @JoePetersLab www.embl.org/about/info/c...
- Reposted by Patricia GerdesBluesky tip for newbies: Bluesky has no real algorithm. Likes here do nothing but show the poster that you enjoyed their content. That kindness is always going to be appreciated by creators, but if you want to help to boost something here, you have to repost it so others see it. 🙂
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- Reposted by Patricia GerdesScraping who is on the platform working on #TransposableElements or other types of #RepetitiveDNA Have fun! go.bsky.app/7t5GQAPat://did:plc:ebur4kpwnz66tpsbldned4bo/app.bsky.graph.starterpack/3lamuxwqbvg2g
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- We had a great time at #UniStemDay2024 explaining to high school students how we study human brain evolution using human and monkey brain organoids and looking at gene expression 🧠🐒🔬🧬 w/ @lcastilla30.bsky.social and Nino Pandiloski @lundstem.bsky.social
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- First sequencing run on our new P2 Solo! So exciting 🤩🧬 @nanopore.bsky.social @jakobssonlab.bsky.social #TEsky
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- Had a great time at the #EMBOMobileGenome conference in Heidelberg 🇩🇪 this week! Lots of interesting talks and also a lot of fun! 🧬🤓 (including some great autumn vibes 🍂)
