PARCC
Paris Cardiovascular Research Center
- Reposted by PARCCDon’t overlook the kidney in SARS-CoV-2 pneumonia—even in the absence of overt acute kidney injury @olilen.bsky.social, Pierre-Louis Tharaux & team report on a strong association between kidney-derived proteins and IL-10 levels and mortality: doi.org/10.1172/jci....
- Reposted by PARCCercsg2026.com A stimulating scientific event to present and discuss #kidneydisease #science4health #pathomechanisms #translationalresearch #emergingtherapies and more! The European kidney community will convene in Paris from April 9-12
- Reposted by PARCCUne nouvelle étude menée par des scientifiques de l’Inserm montre que le feedback pourrait augmenter la prise de risque sans rendre les décisions plus optimales. Lire le communiqué : presse.inserm.fr/prise-de-ris...
- Reposted by PARCC[This post could not be retrieved]
- Reposted by PARCC[This post could not be retrieved]
- Reposted by PARCCScientists have developed rearrangeable robotic modules that can “bloom” like flowers to shade a sunlit room by sensing light levels and adapting collectively. Learn more in #ScienceRobotics: scim.ag/4jMQais
- Reposted by PARCCThank you Irene Fernandez-Ruiz for this great piece of commentary in @natrevcardiol.nature.com on the IVORY trial published in @natmed.nature.com Main paper can be found here: rdcu.be/eX8W3 @ziadmallat.bsky.social @18fdg.bsky.social @vpd-hlri.bsky.social @medcambridge.bsky.social
- Reposted by PARCC"Research is messy. … Trying to protect students from that reality does them a disservice." On #InternationalDayOfEducation, take a look back at this Working Life essay on teaching students about scientific failure. scim.ag/4sTaQcH
- Dr O. Lenoir, Dr PL. Tharaux @PARCC and colleagues reveal that levels of circulating kidney injury markers and IL-10 identify non-critically ill patients with COVID-19 at risk of death. Learn More: insight.jci.org/articles/vie...
- Reposted by PARCC"One email at a time, one informational interview after another, I became comfortable, confident, and strategic in building my network of mentors." One mentor isn’t enough, wrote Erika Moore in this 2021 Working Life essay. scim.ag/3Zfm0e8 #NationalMentoringMonth
- Reposted by PARCCAre you a grad student struggling with a blank page? These strategies could help go.nature.com/4jGEmhO
- Reposted by PARCCNature research paper: Artificial intelligence tools expand scientists’ impact but contract science’s focus go.nature.com/4pA9hNZ
- Dr JP Empana and colleagues @PARCC investigated the prevalence, temporal trends and associated factors of overweight and obesity among adults in the WHO African region. Read more: gh.bmj.com/content/11/1...
- Reposted by PARCCExcited to share our latest work published in @pnas.org! 🎉 Our study shows that blood-borne S1P actively maintains vascular resistance, systemic BP and heart function in mice, with distinct contributions from different circulating S1P pools www.pnas.org/doi/10.1073/... @parcc-inserm.bsky.social
- Reposted by PARCC[This post could not be retrieved]
- Reposted by PARCCDans un essai clinique de phase 2, une équipe de l'Inserm montre l’efficacité d’un nouveau traitement pour réduire l'inflammation chronique ou résiduelle qui peut être observée après un syndrome coronaire aigu (SCA). Lire le communiqué : presse.inserm.fr/syndrome-cor...
- Reposted by PARCC📢Candidatez à la prochaine édition du Challenge Starthèse qui accompagne les doctorants & jeunes chercheurs dans la valorisation de leurs expérience de thèse, compétences doctorales et travaux de recherche 📆Fermeture des candidatures : 09/02 👉 swll.to/iZT4L
- Dr E Camerer and colleagues @PARCC uncover an essential role for circulating S1P in maintaining blood pressure and left ventricular systolic function. They also highlight distinct functions for the pools of S1P bound to HDL or to albumin. www.pnas.org/doi/10.1073/...
- Pr Z Mallat @PARCC and colleagues show that, in patients with acute coronary syndromes, low-dose IL-2 safely increases Treg cell levels and reduces arterial inflammation. Learn More: www.nature.com/articles/s41...
- Reposted by PARCCA 3D printed guide that reconnects right vagus nerve and heart preserved cardiac function and helped regrow resected nerve in minipigs, with therapeutic potential for thoracic surgery and transplantation. Learn more in #ScienceTranslationalMedicine: scim.ag/49eworw
- B. Gaye and E. Marijon @PARCC, in collaboration with colleagues from the ERADICATE Consortium (Ending Rheumatic Heart Disease through Advanced Diagnosis, Intervention, Care, Access, Treatment, and Equity), are leading a strategy aimed at eradicating rheumatic heart disease. doi.org/10.1093/eurh...
- A Eichmann and Colleagues @PARCC showed that endothelial ROCK1 and 2 maintain junctional integrity and ensure proper angiogenesis and lumen formation. These data also indicate the need for careful consideration when using ROCK inhibitors in disease settings. doi.org/10.1093/cvr/...
- Pr D Smadja @PARCC calls to action for Health desinformation. the next battle for public health will be waged not only in hospitals and laboratories but also in the information spaces where truth competes with virality. It is time for science to go viral—for the right reason!
- Reposted by PARCCDans une nouvelle étude des scientifiques de l'Inserm ont analysé comment le système lymphatique se dérègle dans l’insuffisance cardiaque. Ils ont, pour la première fois, identifié les mécanismes responsables de ce dysfonctionnement. Lire le communiqué : presse.inserm.fr/decouverte-d...
- Pr D Smadja @PARCC and colleagues confirmed the absence of vascular benefit of Hydroxychloroquine (HCQ) treatment, reinforcing evidence against HCQ’s clinical utility in COVID-19 and underscoring the need for alternative endothelial-targeted approaches. link.springer.com/article/10.1...
- Reposted by PARCCL’ANR participe au nouvel appel à projets transnational du partenariat européen pour la médecine personnalisée, EP PerMed : "Médecine Personnalisée pour les maladies #cardiovasculaires, #métaboliques et #rénales" #CARMEN2026 📆 10/02/2026 (pré-propositions) ➡ anr.fr/CARMEN2026
- Reposted by PARCCSusan Monarez was fired after less than a month as Director of the CDC for holding the line on scientific integrity She is part of Nature's 10 - our list of people who shaped science in 2025 go.nature.com/48FnHpx
- Reposted by PARCCAcademia is unprepared for the rise in chatbot use among students go.nature.com/4iPtlKz
- Pr A Loupy team @PARCC has developed a novel FFPE-based molecular diagnostic system which accurately identified cardiac allograft rejection. academic.oup.com/eurheartj/ad...
- H Ait-Oufella @PARCC and colleagues review the role of trained immunity in cardiovascular disease.
- Reposted by PARCCArtificial intelligence promises rapid and polite feedback on papers — but we must first review the reviewer, says Giorgio F. Gilestro go.nature.com/3McjUsw
- Reposted by PARCC🗞️ À découvrir aujourd’hui dans @lexpress.fr : "Le financement de nouveaux projets de recherche est menacé : l'alerte de Claire Giry (ANR)".
- "Le financement de nouveaux projets de recherche est menacé" : l'alerte de Claire Giry (ANR) ➡️ l.lexpress.fr/xDq
- Reposted by PARCC‘Emerald’ or ‘Paris’ green was once a highly popular pigment among painters, but the chemistry behind its slow decay over time has been unclear go.nature.com/4paYhqU
- JP Empana and colleagues @PARCC assess the prevalence, awareness, and treatment of hypertension in 37 african countries from 2003 to 2022 | JACC www.jacc.org/doi/10.1016/...
- Reposted by PARCC"Encouragingly, 89% of the public viewed scientists as intelligent, 65% thought they were honest, and 65% believed they were working to solve real-world problems." Richard Horton's latest Offline: Is there really a trust crisis in science? tinyurl.com/2x59cw6b
- Reposted by PARCCLa cérémonie des Prix Inserm 2025 a récompensé 5 lauréates et lauréats !
- Reposted by PARCCStill two more #ParisPostdocsSeminars before the end of the month! 🧪Dr. Arianna Giannetti 📆 Nov 25th 📍 @parcc-inserm.bsky.social | #Stress #Thrombosis 🧪Dr. Camila Valenzuela-Montenegro 📆Nov 27th 📍 @institutcurie.bsky.social | #Salmonella #EpithelialCells Don't miss them! #Science #Postdoc
- Reposted by PARCCIn a small study, gene editing slashed blood levels of two fats that contribute to clogged arteries and ramp up risks of heart disease, potentially for life. scim.ag/486nL1o
- Reposted by PARCCPeripartum cardiomyopathy is now the leading cause of maternal death in many parts of the world. A Seminar summarises current knowledge of peripartum cardiomyopathy genetics, pathophysiology, diagnostic approaches, medical management, and outcome: spkl.io/63320AdQNn
- Reposted by PARCCCanal Détox, c'est l'initiative de l'Inserm qui lutte contre les fausses informations en santé. Découvrir la série : presse.inserm.fr/le-canal-det...
- Reposted by PARCCA new study finds that women’s names filled just 23% of author slots in a sample of nearly 900 retracted articles published in medical journals between 2008 and 2017 go.nature.com/49pgmN7
- A Loupy @PARCC and colleagues provide the first long-term physiologic, immunologic, and infectious disease monitoring of a pig-to-human kidney xenotransplant. Please read more: doi.org/10.1038/s415...
- Reposted by PARCCC'est aujourd'hui ! ⬇️
- Reposted by PARCCNew online! Integration of cardiovascular and mental health: from concepts to the clinic #CardioSky
- Reposted by PARCCAre geopolitical tensions affecting research output? go.nature.com/4o229JK
- Reposted by PARCCThe 2025 @lancetcountdown.bsky.social report reveals climate change inaction is costing lives and livelihoods, and harming the economy. During #COP30, explore recommendations for action: spkl.io/63324AbjGM #LancetClimate25
- Reposted by PARCC"Belém offers a chance to place health at the centre of climate governance and confront the increasingly ominous consequences of delay." Ahead of #COP30, a new World Report: spkl.io/63326AbDDC
- Reposted by PARCCWhen asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: scim.ag/4qFrPON
- JP Empana and X Jouven Team @PARCC reveal that sex differences in out-of-hospital cardiac arrest characteristics and outcomes were observed across all age groups and became more pronounced with increasing age, consistently indicating a better prognosis for males. heart.bmj.com/content/earl...
- Reposted by PARCCNew online! Gene–environment interactions in the pathogenesis of cardiovascular disease #CardioSky
- Reposted by PARCCÀ l’occasion des 10 ans des attentats du 13 novembre, l’Inserm vous propose un magazine exceptionnel sur le trouble de stress post-traumatique (TSPT) et ses effets sur la mémoire. 🗓️ RDV le 13/11 à 13h00 en direct sur la chaîne YouTube de l'Inserm pour ce nouveau n° de 30’ santé.
- A Eichmann, K Boye and colleagues @PARCC and @Yale University of Medicine establish Netrin-1 as a promising therapeutic target for preventing blood-retina barrier breakdown in retinal vascular diseases. link.springer.com/article/10.1...
- Reposted by PARCCInterested in working with us? @upcite.bsky.social @parcc-inserm.bsky.social @esendocrinology.bsky.social @sfendocrino.bsky.social @jedi-sfe.bsky.social @ese-eyes.bsky.social @a5-adrenal.bsky.social www.linkedin.com/feed/update/...
- Great discoveries often arise from work that was looking for something completely different. www.nature.com/articles/d41...
- Reposted by PARCCFunders must recognise that great discoveries often come from studies that seeks to advance knowledge for its own sake go.nature.com/3X5lbUg
- Reposted by PARCC[Préannonce] Fin novembre, l’ANR participera au nouvel appel à projets transnational du partenariat européen pour la médecine personnalisée, EP PerMed "Médecine Personnalisée pour les maladies #cardiovasculaires, #métaboliques et #rénales" (#CARMEN2026) ➡ anr.fr/fr/detail/ca...
- A Loupy @PARCC and colleagues of the international consortium of digital twins in healthcare and medicine reveal distinct biological clock patterns across different life stages. www.nature.com/articles/s41...
- P Breillat and B Terrier from PL Tharaux team @PARCC showed that NK-cell dysfunction in VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome contributes to increased susceptibility to severe infections. doi.org/10.1182/bloo...
- Pr MC Zennaro @PARCC and colleagues from the European EndoCompass project initiative established a research roadmap for adrenal and cardiovascular endocrinology. doi.org/10.1093/ejen...
- Reposted by PARCCA gene that causes obesity is paradoxically linked to a reduced risk of having heart disease and high cholesterol, according to an analysis of thousands of people with obesity. go.nature.com/4o2YDzC
- Reposted by PARCCIn this Communications Biology article, authors modeled cardiomyocyte geometry revealing that mitochondrial–sarcoplasmic architecture enhances respiration by facilitating ion and lipid transfer for efficient cardiac metabolism🫀 @parcc-inserm.bsky.social doi.org/10.1038/s420...
- C Jouve and colleagues from Team Hulot @PARCC demonstrate that mitochondrial-sarcoplasmic architecture and geometry are critical spatial features that ensure bioenergetic efficiency of cardiomyocytes rdcu.be/eKD1n
- Reposted by PARCCHopes of securing a United Nations treaty on plastic pollution are fading after the final round of negotiations ended without an agreement. go.nature.com/3J74xjN
- Reposted by PARCCNew online! The global cardiovascular–liver–metabolic syndemic: epidemiology, trends and challenges #CardioSky
- Reposted by PARCCBook review 📚 The cutting-edge medical approaches that could transform ageing go.nature.com/46Fu2Sp
- Pr JS Hulot team @PARCC revealed that CD51 contributes to the immune-fibrotic axis driving heart failure progression under pressure overload. www.sciencedirect.com/science/arti...
- Reposted by PARCCMineralocorticoid receptor inhibition in parietal epithelial cells prevents focal segmental glomerulosclerosis and crescentic glomerulonephritis. doi.org/10.1016/j.kint.2025.07.037 #OpenAccess #NephSky #MedSky #CKD #FSGS #chronickidneydisease @parcc-inserm.bsky.social @rwth.bsky.social
- Team Loupy@PARCC characterizes the Immune Response in Pig-to-human Heart Xenografts Using a Multimodal Diagnostic System | Circulation www.ahajournals.org/doi/10.1161/...
- Reposted by PARCC🚨 New paper from the lab in ATVB Dexamethasone protects against COVID-19 endothelium-induced coagulopathy 🦠🔥🫁🩸 @davidmsmadja.bsky.social @hopitalpompidou.bsky.social @upcite.bsky.social @parcc-inserm.bsky.social @ahajournals.bsky.social @inserm.fr www.ahajournals.org/doi/10.1161/...
- Reposted by PARCCInspiring and fun meeting with outstanding @rkramann.bsky.social at the @parcc-inserm.bsky.social #Masterclass @olilen.bsky.social with the community, #our KVIM team and young early career researchers ! Thank you Rafael!
- D Smadja team @PARCC shows that Dexamethasone Suppresses Endotheliopathy and Endothelial-Induced Coagulopathy in COVID-19 | Arteriosclerosis, Thrombosis, and Vascular Biology www.ahajournals.org/doi/10.1161/...
- PL Tharaux team and MC Zennaro team @PARCC show that mineralocorticoid receptor inhibition in parietal epithelial cells prevents focal segmental glomerulosclerosis and crescentic glomerulonephritis. - Kidney International www.kidney-international.org/article/S008...
- N Bouatia-Naji and T Berrandou @PARCC participate to a study showing that KLK15 alters connective tissues in hypermobile Ehlers-Danlos syndrome: iScience www.cell.com/iscience/ful...
- Reposted by PARCCThis week on the Nature Podcast 🔊 This AI tool predicts your risk of 1,000 diseases — by looking at your medical records go.nature.com/46rd492
