Concomitant medications can influence ICI outcomes & represent a modifiable prognostic factor. Now, Young & colleagues explore immunomodulatory effects of common drugs + supplements & propose strategies to integrate this knowledge into clinical care.

The impact of concomitant medications on treatment outcomes in patients with cancer receiving immune checkpoint inhibitors - Nature Reviews Cancer
Concomitant medications are emerging as a modifiable prognostic factor for immune checkpoint inhibitor treatment outcomes. This Review by Stone et al. highlights the potential immunomodulatory interactions of commonly prescribed medications and supplements, and proposes strategies to make better use of this information to guide clinical care.