Maximilian Billmann
TT Prof University clinic Bonn | former postdoc UMN CS | PhD DKFZ | CompBio | CRISPR screening | Data analysis | Networks
- This is such hard news to process. Such an amazing scientist and inspiration for so many of us. www.embl.org/news/embl-an...
- Darwin's regrets: "If I had to live my life again I would have made a rule to read some poetry and listen to some music at least once every week.. The loss of these tastes is a loss of happiness, and may possibly be injurious to the intellect and more probably to the moral character"
- @colmr.bsky.social takes the stage to share the work of his group that aims to understand and predict synthetic lethality between paralogs in cancer
- The 2nd @eurocancerdepmap.bsky.social meeting is starting with introduction from @francescoiorio.bsky.social ! Full day of exciting talks ahead. Stay with us for live updates @humantechnopole.bsky.social
- The Synthetic Lethality and Innovations in CRISPR Screening session begins with @manuelkaulich.bsky.social telling us about exciting CRISPR libraries they have developed and how nuclear mRNA processing can mask the CRISPRko phenotypes @eurocancerdepmap.bsky.social
- Kudos to our Flavio Passante for winning with his team the REMEDi4ALL Hackathon in Barcellona! Researchers from 10 countries tackled real-world challenges in drug repurposing for rare neurodevelopmental disorders, spanning the whole pipeline from early target discovery to market access.
- Last week we had the pleasure of hosting @maxbillmann.bsky.social at @humantechnopole.bsky.social for an inspiring seminar on genetic interaction maps an networks. Fantastic to learn how CRISPR screens and integrative analyses can illuminate the logic of genetic dependencies. A big thank you Max 👏
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- 🎉🏆 Our third featured winner from the #NetBio #Cytoscape Visualization Contest submitted by Michael Costanzo. This beautiful visualization maps genetic interaction profile similarities among 3,784 human genes in HAP1 cells and their role in biological processes. doi.org/10.1101/2025...
- Monumental effort from @maxbillmann.bsky.social and colleagues, quantifying genetic interactions among 4 million human gene pairs. Lots of features associated with genetic interaction & GI degree conserved from yeast. www.biorxiv.org/content/10.1...
- Paper in Nature 150 years ago. Beats reading any single-cell experiment…
- Variant characterization in the intrinsically disordered human proteome - here is how we did it using short linear motif prediction, AlphaFold, and experimentation. Check out our preprint: www.biorxiv.org/cgi/content/...
- Loss-of-function mutations cannot simply eliminate some paralogous genes. Duplicated genes encoding homomeric proteins interfere with each other, leading to negative selection on the paralogs, even if they are fully redundant. See our new findings here: www.biorxiv.org/content/10.1...
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- Have you discovered the Night Science Podcast yet? @nightsciencepod.bsky.social
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