Maximilian Billmann
TT Prof University clinic Bonn | former postdoc UMN CS | PhD DKFZ | CompBio | CRISPR screening | Data analysis | Networks
- And more isogenic CRISPR screens coming out of Toronto @sickkidsto.bsky.social, this time by Mike Tyers and team - congrats! www.biorxiv.org/content/10.6...
- Great new work from @colmr.bsky.social predicts a cancer dependency map for paralogs: doi.org/10.64898/202....
- Perhaps one of the most anticipated data in my recent memory- amazing talk by Carmen from @sangerinstitute.bsky.social at @eurocancerdepmap.bsky.social
- We start with Carmen Herranz-Ors from @sangerinstitute.bsky.social giving us an overview of the impressive work done to generate Tumour Organoid Biobank and develop a 3D Dependency Map @eurocancerdepmap.bsky.social
- Truly inspiring talk by @icrlordlab.bsky.social at @eurocancerdepmap.bsky.social
- We continue with the talk from @icrlordlab.bsky.social focusing on the complexity of synthetic lethality in cancer and how we can move forward in exploiting it @eurocancerdepmap.bsky.social
- Reposted by Maximilian BillmannTF-MAPS: fast high-resolution functional and allosteric mapping of DNA-binding proteins by @XianghuaLi2 Are Transcription Factors really 'undruggable'? www.biorxiv.org/content/10.1...
- "...predicting responses to unseen perturbations is substantially harder than standard metrics suggest". I am not surprised. www.nature.com/articles/s41...
- Can you find therapeutic targets for cardiomyopathies using simple, clean genetics in a human cell line? www.nature.com/articles/s41...
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- Reposted by Maximilian BillmannI’m excited to highlight our latest paper, just published in Cell 🎉 We report the existence of a previously uncharacterized signaling pathway that is responsible for activating cell death upon loss of gene expression. 1/n 🧪 www.cell.com/cell/fulltex...
- Reposted by Maximilian BillmannVariant characterization in the intrinsically disordered human proteome - here is how we did it using short linear motif prediction, AlphaFold, and experimentation. Check out our preprint: www.biorxiv.org/cgi/content/...
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- Reposted by Maximilian BillmannOur "Atlas of Variant Effects 2030 Roadmap" is live: zenodo.org/records/1542... 1/n
- Reposted by Maximilian BillmannJason Moffat at #VariantEffect25
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