Matyas Bubna-Litic
Interested in mechanobiology, morphogenesis, organisers and synthetic embryo models.
Research Fellow in Mongera lab UCL | PhD in Mayor and Charras labs | YEN Committee
- Reposted by Matyas Bubna-LiticJob alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M
- Reposted by Matyas Bubna-LiticExcited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
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- Reposted by Matyas Bubna-LiticWe're in love with this cover image! 🧡 Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024: www.sciencedirect.com/journal/cell...
- Reposted by Matyas Bubna-Litic#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you. www.biorxiv.org/content/10.6...
- Reposted by Matyas Bubna-LiticPleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking. It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems. Preprint: www.biorxiv.org/content/10.6... [1/6]
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- Reposted by Matyas Bubna-LiticSearching for physical principles of morphogenesis In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory doi.org/10.1242/dev....
- Happy (and spooky) #FluorescenceFriday Switching from frogs (which are underrated btw) to zebrafish has really made me appreciate transparent tissues! 🐟 28 hpf, ⚪ nuclei, 🔴 F-actin
- Reposted by Matyas Bubna-Litic📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome! Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
- Reposted by Matyas Bubna-Litic1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details
- Pretty cool
- 🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
- Reposted by Matyas Bubna-LiticOur new paper is out in Dev Biol! 🎉 🐸🧬 We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning 👉 Read more here: doi.org/10.1016/j.yd... @devbiol.bsky.social @biouea.bsky.social
- Reposted by Matyas Bubna-LiticMouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
- Thank you for sharing! I'd like to highlight the concept of embryonic 'actuation' where a mechanical state change is caused by cells acting on each other through mechanics and/or biochemical signals but importantly not mediated by fate transitions.
- Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview buff.ly/Ea2ZoFg
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- Reposted by Matyas Bubna-Litic✨Not a rainbow trout… a rainbow zebrafish 🌈 🐟 The expression of 10 different genes simultaneously including Hox genes along the body axis, somites, brain regions, skeletal muscle, and heart 🔬Image by Alice Sherrard, Gabby Jerz & Nipam Patel 🧪 #FluorescenceFriday
- Reposted by Matyas Bubna-Litic🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio
- Reposted by Matyas Bubna-LiticDev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social thenode.biologists.com/jobs/postdoc...
- Reposted by Matyas Bubna-LiticGot stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...
- ✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪 #FluorescenceFriday #DevBio
- Reposted by Matyas Bubna-LiticInteresting review about the role of ECM in development!
- Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development. doi.org/10.1016/j.cd...
- Reposted by Matyas Bubna-LiticWe are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei... Please re-post 🙏
- Reposted by Matyas Bubna-LiticThrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch
- Reposted by Matyas Bubna-LiticVery happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
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- Reposted by Matyas Bubna-LiticA cryosection immunofluorescence image of a Xenopus embryo showing fibronectin in 🔵, DAPI in ⚪, and Sox9 - a marker of the neural crest in 🟠. Image credit: Kai Weissenbruch from UCL #FluorescenceFriday #devbio
- Reposted by Matyas Bubna-Litic🪼 How did the animal body plan evolve? This ‘fundamental’ study in Clytia sheds light on how Wnt3 coordinates both gene expression and planar cell polarity during axis formation, offering key insights into the origins of morphogenesis. buff.ly/e1Un958 #DevBio
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- BSDB Bridging mechanics and genetics in early development at University of Warwick was great fun and I am grateful for the opportunity to present my PhD work.
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- Reposted by Matyas Bubna-LiticNext Thurs, join us for the next Western VGZT 🌙 🗓️ Thursday, June 19 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Featuring: @jesseveenvliet.bsky.social 👉Exploring physiological constraints by sculpting with stem cells @sermenchero.bsky.social 👉What marsupials can teach us about time
- Reposted by Matyas Bubna-Litic📣 New paper out! How do thousands of cells shape the emergent geometry of the avian embryo? We identify distinct, independently controllable mechanisms that contribute to embryo size and shape. @alex-plum.bsky.social @bensteventon.bsky.social @Guillermo Serrano Najera www.nature.com/articles/s41...
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- We had a lot of great entries in the YEN Image Competition. Some of these made it to the top 10 after a vote by developmental biologists attending the YEN 2025 Conference. Check them out here:
- See the winners of the YEN Image Competition 2025. Thanks for everyone who sent us their amazing embryology images! #yen2025 thenode.biologists.com/yen-image-co...
- Reposted by Matyas Bubna-LiticSee the winners of the YEN Image Competition 2025. Thanks for everyone who sent us their amazing embryology images! #yen2025 thenode.biologists.com/yen-image-co...
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- Reposted by Matyas Bubna-LiticStarting the short talk session we have Jake Cornwall Scoones from the @CrickLab on using NeMECiS to explore and engineer synthetic CREs to modulate gene regulatory behaviour. Check out their pre-print and workshop!
- Reposted by Matyas Bubna-LiticThank you to everyone who has registered to attend YEN 2025! You can still register for online attendence to hear talks and look at online posters. We have sent out a programme to our attendees so if you haven't heard from us just email us or reach out on social media. #yen2025
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- If you care about mechanics in biological systems give IPLS a follow!
- 📢Registration is open for our IPLS Annual Symposium, 11th June 2025! We will showcase exciting #interdisciplinary #research performed by IPLS researchers and collaborators. Limited spaces, register early to avoid disappointment 👇 ucl.ac.uk/physics-livi...
- Reposted by Matyas Bubna-LiticWe are happy to announce student and postdoc speakers. Thanks to all who submitted an abstract! #yen2025
- Register now to attend YEN 2025. Looks like an amazing line up of speakers! #yen2025
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- Happy #MicroscopyMonday! I was optimising some stainings a couple years ago (this one is Stage 32 with sodium borohydride to reduce autofluorescence). Any #Xenopus people know what the rosette-looking clusters around the eye are doing? By the way, check out YEN Image Competition #YEN2025 ;)
- Great opportunity to highlight your research and celebrate the great imaging possibilities in dev bio! #YEN2025
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