Living Physics Lab
Biological theory | “Cell learning” | Function spaces | Projection operators | Manifolds | Dynamics | Behavior | Evolution
livingphysics.org
Cambridge, UK
Living Physics Feed: tinyurl.com/living-physics
- This looks to be a very nice conference, would love to see some of you there! intcha26.sciencesconf.org
- Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development. Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
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- Did you hear about the two muffins baking in an oven? One said "Phew, it's hot in here. The other said, "Holy shit a talking muffin!"
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- Oh this is useful! Can you share the outcome?
- It continues to be weird to me that adult CNS neurons have a single, nonmotile cilium just hanging out, maybe acting as a site for receptor expression. Like a little extra antenna that we all just ignore in our drawings of neurons. www.cell.com/neuron/fullt... pmc.ncbi.nlm.nih.gov/articles/PMC...
- New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
- This looks awesome! #livingphysics
- Published: Noise equals control. I detail an explicit mapping between stochastic systems and control theory, showing how goal-directed behaviour arises from purely causal stochastic systems. Illustrated with stochastic resonance & Brownian ratchets journals.aps.org/pre/abstract...
- In crater Lake Masoko one fish species is splitting into shallow and deep-living ecotypes occupying different light environments. New research shows their visual systems are diverging, and how colours of male eggspots have changed to maximise their visibility. doi.org/10.1093/molb...
- What the life in the UK test is: When was the battle of Agincourt? A) 1215 B) 1415 C) 1348 D)1400? What the life in UK should be: You: Shall we bring something? Maybe a pasta salad or a green salad? Friend: That’s fine, we can make fish pie with peas..
- A) Friend would like you to bring a salad B) Friend is letting you know what they are making and leaving it up to you C) Friend is fine without a salad D) A salad killed your friend's mum and under no circumstances should you bring a salad
- You had me at “low dimensional behavioral manifold” 😍 #livingphysics
- Complex behaviour is not limited to animals! Here we map the entire spectrum of waveforms dynamics on a quadriflagellate single cell with 4x 70um (!) #cilia, to a low dimensional behavioural manifold with surprising structure! #protistsonsky All revealed in our new preprint doi.org/10.1101/2025...
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- There was also an iGem project that made E. coli smell like mint in exponential phase and banana in stationary phase www.sciencedirect.com/science/arti...
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- I think the link is broken now ☹️
- A great podcast episode about this featuring @scientificdiscovery.dev
- A year after its breakout public health moment, 'miracle drug' lenacapavir has been approved by the FDA and recommended by the WHO. The drug is a long-lasting shot that provides almost 100% protection against HIV infection. buff.ly/E5zOvGl #ShareGoodNewsToo
- This will be quite fun! Join us in September for "“Physics of Adaptation & Decision Making in Biology” www.fluidlab.nl/padm25
- My first first author manuscript has posted! I’m very excited to share SWIF-TE with yall. It is a fast, memory efficient tool to identify novel TE insertions from short-read data. 🧬 #TEworldwide #transposons
- SWIF-TE: identifying novel transposable element insertions from short read data biorxiv.org/content/10.1101/202…
- How can cells self-organize rapidly into complex patterns during development? Let’s explore a powerful and underappreciated mechanism: Directed Cell Migration (DCM). Preprint @biorxivpreprint.bsky.social : doi.org/10.1101/2025... 👇Thread 🧵(1/11)
- I think that this pic from the original paper illustrates very well how fast Diamond2 is. I'm also waiting for the final publication of the Diamond Deepclust DB that is the largest protein seq DB AFAIK Sensitive protein alignments at tree-of-life scale using DIAMOND www.nature.com/articles/s41...
- I think that this pic from the original paper illustrates very well how fast Diamond2 is. I'm also waiting for the final publication of the Diamond Deepclust DB that is the largest protein seq DB AFAIK Sensitive protein alignments at tree-of-life scale using DIAMOND www.nature.com/articles/s41...
- How far can you compress a complex system? 🚨 In our latest paper we collapse high-dim compartmental models (from epidemics to ecosystems) into a single 1-D equation using quantum-inspired math, exposing universal phase transitions #ComplexSystems 👇👇👇 journals.aps.org/prx/abstract...
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- Thanks!
- Mind sharing where you picked these up and what brand/manufacturer they are!
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- Great! Your talk on finding exactly the right age rock that was close enough to the surface to hunt for Tiktaalik fossils has stuck with me for decades. I’m from PA and I still haven’t managed to get to red hill road cut to try to search myself, but it’s on my bucket list.
- Spot the pattern! Hyperdisorder is a phenomenon that combines order at the microscopic scale with disorder at the macro level. It's now been observed for the first time in a biological system, showing up in the spots on the skin of young squid. 🧪 ⚛️ physicsworld.com/a/hyperdisor...
- (1/4) I’m happy to introduce our new work led by PhD student Akira Kawano (not on Bluesky), which explores social behavior as mutual prediction, quantified by the decomposition of information (PID) between the past and future of a multi-organism system: doi.org/10.1101/2025...
- PNAS special feature on Collective Artificial Intelligence and Evolutionary Dynamics Contributions from scientists in machine learning, evolutionary game theory, and their growing intersection. www.pnas.org/toc/pnas/122...
- Are you interested in research on microbial communities, how microbes come together and co-exist in nature, and what “community-level” functions they display? Join us for an upcoming workshop, Microbial Communities: Energetics and Dynamics Across Space and Time! www.nitmb.org/microbial-co...
- 🧵 🧪 1/ Hi! I’m excited to share our latest work, now on arXiv: Repulsive particle interactions at cellular interfaces enable selective information processing (arxiv.org/abs/2506.14739) Where we explore how the physical properties of living systems can help cells process spatial information.
- Another day, another @wgilpin.bsky.social paper I simply must read, I’m not finished with Panda yet! #livingphysics
- Does stability matter in biology? My article on the cover of this month’s @PLOSCompBiol explores how large ecosystems develop supertransients, a manifestation of computational hardness (1/N) doi.org/10.1371/jour...
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- Nicking mutagenesis with a very long mutagenic oligo? You’d have to talk to an expert about annealing temp etc for very long oligos pmc.ncbi.nlm.nih.gov/articles/PMC...
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- I’ve found this blog incredibly useful for environment proofing sensors! thecavepearlproject.org/2023/03/17/w...
- Temperature is so important for plants that they have come up with many independent temperature sensors. Curious? Read more in this review by former WeigelWorld members Sridevi Sureshkumar & Suresh Balasubramanian. #plantscience www.science.org/doi/10.1126/...
- Please join BPPB on Friday June 13 @ 11 EDT for exciting talks by Rachel Bennett (Analytical framework for coordination of metachronal cilia) & Emily Gehrels (How embryos generate polarized tissue flows during development). For more information, please visit sites.google.com/view/bppb-se....
- 📣 New review! Dynamical systems and low-dimensional geometric structures in phase space help rationalize how embryos develop form and function, from large datasets. We focus on morphogenesis, cell differentiation, and their interconnection. @alex-plum.bsky.social sciencedirect.com/science/arti...
- Decomposing Predictive Information in Social Dynamics biorxiv.org/content/10.1101/202…
- This is cool - bacteria wrap their flagella to propel themselves through narrow passages www.biorxiv.org/content/10.1...
- I'm excited to share our latest pre-print on proximity proteomics of primary cilia in human hypothalamic neurons, led by Viviana Macarelli, which revealed proteins involved in synapses and neurotransmission and the obesity-associated GPCR LPAR1. Details at bit.ly/4jcTodq
- Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...
- Emergence and Self-organization in Biological Systems” (ESBS 2025), will be held at the Arnold Sommerfeld Center in the Physics Department of LMU Munich from August 18 to 22, 2025.
- 📣Next Tuesday our online seminar is with Jacopo Grilli (ICTP Trieste) on: ⭐Competition without contingency and functional convergence⭐ Zoom link: iite.info/seminar/ Global times: www.timeanddate.com/worldclock/f... Free for anyone to join and get involved, no need to register - see you there!
