Janusz M. Bujnicki
Structural biology & bioinformatics @IIMCB, policy-for-science & science-for-policy @PAN_akademia @EMBO @acad_euro
- Reposted by Janusz M. Bujnicki⭐NAR Breakthrough! ⭐ 🚀 ALE RNA platform overcomes length limits in #chemicaRNAsynthesis, enabling >200-nt RNAs. Supports sgRNAs and 5′-capped mRNAs with strong translation and precise mods. Site-specific 2′-OMe poly(A) boosts protein expression. 🧬Read more: doi.org/10.1093/nar/... #NARBreakthrough
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- Reposted by Janusz M. Bujnicki💡Your questions, answered. The ERC Plus Grant webpage is now live, and the Q&As on this new funding scheme are available on the website, too. 🔗 ERC Plus Grants 👉 bit.ly/3N7BJcr 🔗 Q&A 👉 bit.ly/4j4G5gA
- 🎉Our new paper out: the 6th update of MODOMICS, marking 20 years of our RNA 🧬modification database. Largest update so far, including >48,000 human RNAs with modification sites, collaboration with Sci-ModoM & Human RNome Project. NAR 2025 doi: 10.1093/nar/gkaf1284 #RNA #Epitranscriptomics #Databases
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- Reposted by Janusz M. Bujnicki📣 Authors wanted! Submit to NARMME's Special Collection on Repeat Expansion Diseases by Jan 2026🧬 🔍Find out more: academic.oup.com/narmolmed/pa... 👉Submit: mc.manuscriptcentral.com/narmme #CallForPapers #Genomics #RareDiseases #NARMME
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- Exciting news for the RNA research community! The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130... #RNA #bioinformatics #RNAstructure #modomics
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- Reposted by Janusz M. Bujnicki🧬 New in NARMME: RNA splicing tweaks rescue tau toxicity in C. elegans. Modifying tri-snRNP proteins rescues tau-induced deficits in transgenic C. elegans, restoring behaviour, neurodegeneration and extending lifespan. Read: doi.org/10.1093/narm... #Alzheimers #RNAsplicing #Neurodegeneration
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- Our new review article on RNA-protein interactions is out: www.sciencedirect.com/science/arti... We highlight recent advances in computational modeling of RNA and RNA–protein complexes, from flexibility and dynamics to AI and quantum-enhanced methods. @iimcb.bsky.social
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- Reposted by Janusz M. Bujnicki⭐NAR Breakthrough!⭐ 🧬 Sun et al. just dropped a high-throughput method to track all #tRNA #modifications across cells & tissues using #massspec. Read the full article here: doi.org/10.1093/nar/... #NARBreakthrough #RNA #tRNA #epitranscriptomics #systemsbiology #therapeuticdiscovery.
- Reposted by Janusz M. Bujnicki❓Do you have expertise in prokaryotic molecular biology, including transcriptional regulation, metabolism, physiology, and protein–nucleic acid interactions? ➡️ If so, apply to become @narjournal.bsky.social's next Executive Editor! Don't miss the opportunity: oxford.ly/4f5p57M
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- Reposted by Janusz M. BujnickiVery promising news on the next seven-year EU budget, with a proposed substantial increase for Horizon Europe including the ERC. We are analysing the other parts of this proposal in more detail. @Vonderleyen @EZaharievaEU research-and-innovation.ec.europa.eu/news/all-res...
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- Reposted by Janusz M. Bujnicki📢 The 23rd annual NAR Web Server Issue is live! 🧬 Featuring 72 new web servers across scientific & medical fields. 👏 Huge thanks to all authors, editors and reviewers! 🔗 Issue: lnkd.in/dVyUdAVN 📝 Editorial: lnkd.in/d9qh3QEh #NARWebServer #GeneticSoftware #MolecularBiology #OpenAccessIssue
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- Reposted by Janusz M. Bujnicki📢Nowe zasady open access w NCN: większa elastyczność – ta sama idea. ❗️Z dniem 26 czerwca odeszliśmy od wymogu publikowania wyłącznie w otwartym dostępie, jednak nadal rekomendujemy otwarte udostępnianie wyników badań. Szczegóły➡ ncn.gov.pl/aktualnosci/... #openaccess #projektyncn
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- Join us in Frankfurt, Aug 4–9, for the 2025 Human RNome Project Workshop! Focus: RNA modifications, mass spec, direct RNA seq & more. Help shape the roadmap to decode the human RNome. 🔗 humanrnomeproject.org/2025-workshop-in-germany #RNA #HumanRNomeProject
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- Reposted by Janusz M. BujnickiAre you based in the U.S. 🇺🇸 or Canada 🇨🇦 and thinking of doing research in Europe? ERC grants offer up to €4.5 million to support groundbreaking, investigator-driven frontier research in all fields. Watch the dedicated info session for researchers in your region👉 youtu.be/92QYink1Lik #ChooseEurope
- Today, the ERC formally adopted a decision to increase its support for researchers moving to Europe. On top of its normal grants, the ERC offers 'start-up' funding to help PIs establish laboratories / research teams in Europe. This extra funding is now x2 (up to €2 million!) europa.eu/!6Vdgmp
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- Proud to be part of this interdisciplinary work with @sebastianglatt.bsky.social, Ting-Yu Lin, our teams at @MCB_UJ & @IIMCB_Warsaw, and collaborators from France! #cryoEM + #biophysics + #modeling reveal how #pseudouridine shapes human tRNA structure and stability. 🧬 #RNAmodifications
- tRNAs are small and sport heterogeneous base modifications – yet @sebastianglatt.bsky.social @jmbujnicki.bsky.social Ting-Yu Lin 林亭妤 et al show #cryoEM combined with biophysical & computational approaches can give insights into how #pseudouridine affects human tRNA! www.embopress.org/doi/full/10....
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- The EC published a report on how scientific advice shaped EU policy: from cancer screening to solar radiation modification. I was one of the Chief Scientific Advisors in SAM (2015–2020) and still contribute as an expert. tinyurl.com/dy9ex7d3 #ScienceForPolicy #SAM
- One of the new EU-funded projects will strengthen Evidence-Informed Policymaking (EIPM) in 7 countries, including Poland 🇵🇱. A key step towards building a professional science advice system and smarter, evidence-based policies. #EIPM #ScienceAdvice #TSI #ScienceForPolicy
- The European Commission has published A European Framework for Science Diplomacy. I contributed as a member of one of the five EU Science Diplomacy Working Groups that shaped its recommendations. 🔗 research-and-innovation.ec.europa.eu/news/all-res...
- My favorite scientific journal Nucleic Acids Research is on Bluesky! @narjournal.bsky.social Check it out academic.oup.com/nar/
- 🚀 DesiRNA, our new RNA design tool, solved all 100 puzzles in the Eterna100 benchmark within 24 hours, outperforming all existing RNA design programs! 🧬 🔗 Read about it in Nucleic Acids Research: doi.org/10.1093/nar/... #Science #Bioinformatics #ComputationalBiology #RNA #RNAstructure
- IIMCB is hiring Junior Principal Investigators in computational biology. Deadline for applications: February 2, 2025
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- Reposted by Janusz M. BujnickiHello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!
