IgnatovaLab
A lab of #RNA lovers, obsessed with #tRNA, #mRNA, #ribosomes, and #translational control in health and disease.
- Reposted by IgnatovaLabnow online: academic.oup.com/nar/article/...
- Reposted by IgnatovaLabOur paper on the structural and functional basis of the human dimeric OS9–SEL1L–HRD1 ERAD complex, together with @qilabuva.bsky.social, is now out! Huge congratulations to Leo, Emir, and Elina! www.nature.com/articles/s41...
- Interested in direct tRNA-seq by Nanopore? We developed a new RNA-based barcoding aproach for seq parallelization; it is also cost-saving. Scripts available on github. #tRNA #Nanopore track.smtpsendmail.com/9032119/c?p=...
- What a beatiful study: GCN2 is activated by ribosome collisions
- Reposted by IgnatovaLabTranslation landscape of stress granules | Science Advances www.science.org/doi/10.1126/...
- Reposted by IgnatovaLabThrilled to announce our #preprint on a new factor in the last line of defense in #translation quality control out on #bioRXiv! Spearheaded by fantastic PhD student @kaushikiyer.bsky.social, supported by Chloé Walter, Alina Kraft, Max Müller and Lena Tittel.
- Jlp2 is an RQC complex-independent release factor acting on aberrant peptidyl-tRNA, protecting cells against translation elongation stress biorxiv.org/content/10.1101/202…
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
- A new review on suppressor-tRNA therapies, we wrote with Suki Albers 👇🏻 www.sciencedirect.com/science/arti...
- Reposted by IgnatovaLabHere, we show that bacterial ribosomes—often viewed as conserved drug targets—actually vary across species due to extensive sequence variation in their drug-binding residues. In some cases, this divergence may lead to intrinsic drug resistance in certain bacterial clades: doi.org/10.1016/j.ce...
- Reposted by IgnatovaLabWant to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org: www.embopress.org/doi/full/10....
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLabDie #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3
- Delighted to share our newest publication - beautiful collaboration with Ya-Ming Hou’s lab. If you wonder whether bacterial mRNAs contain m6A (yes they do) and whether it matters (does not seem to) look here 👇🏻 academic.oup.com/nar/article/...
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
- Cells are swapping mitochondria. Wondering whether they also swap much smaller cellular entities, e.g. ribosomes? www.nature.com/articles/d41...
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
- Reposted by IgnatovaLab[Not loaded yet]
