Ufuk Günesdogan
Developmental and Stem Cell Biology lab at the University of Goettingen
- Reposted by Ufuk GünesdoganInstitut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
- Reposted by Ufuk GünesdoganDeadline TODAY January 23 - please join the Systems Biology: Global Regulation of Gene Expression meeting in beautiful @cshlnews.bsky.social (March 11-14). Register and submit your abstract here: meetings.cshl.edu/meetings.asp.... Please Repost!
- Reposted by Ufuk GünesdoganDo not miss this great symposium in Utrecht! Stellar speakers, free registration and fun audience in a great institute!! 🤩 Registration is open now
- Register now for the second Hubrecht Symposium, themed Molecular Machines in Development in Utrecht on March 26, 2026. Visit hubrecht.eu/hubrecht-symposium-2026/ for registration and abstract submission. Abstract submission deadline: February 1, 2026.
- Reposted by Ufuk GünesdoganA major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...
- Reposted by Ufuk GünesdoganLovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...
- Reposted by Ufuk GünesdoganWe have just published a tribute to John Gurdon, reflecting on his scientific legacy and the profound influence he had on generations of developmental biologists. The piece is available open access in Nature Communications: www.nature.com/articles/s41...
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- Reposted by Ufuk GünesdoganWe're very excited to welcome Dr. @sumrubayin.bsky.social from the @gurdoninstitute.bsky.social onto the next episode of the podcast! 🎉 Her lab studies the mouse #cerebellum to better understand the regulation of #neural stem cell behavior. 🧠
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- Reposted by Ufuk Günesdogan🚨 Exciting conference for stem cell aficionados! ‘Frontiers in Stem Cell Innovation’ will bring together experts in stem cell biology from academia & industry to discuss key developments as well as challenges in regenerative medicine and disease modelling. fisci2026.eventbrite.co.uk Please repost 🙏
- Reposted by Ufuk GünesdoganHappy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
- Reposted by Ufuk GünesdoganNew preprint from our lab! What can we learn about the properties of gene regulatory elements by CRISPR’ing a random set of accessible sites in human cells? Find out here: www.biorxiv.org/content/10.1... 👇 1/
- Reposted by Ufuk GünesdoganThrilled to share that our Group Leader Prof. Azim Surani, together with Prof. Davor Solter, has been awarded the 2026 Paul Ehrlich & Ludwig Darmstaedter Prize 🎉 for discovering genomic imprinting—a breakthrough that reshaped genetics and launched modern epigenetics.
- Reposted by Ufuk GünesdoganMost read, I hear! Here is your chance to read what @mariekeoudelaar.bsky.social and I had in mind when writing this together.
- The latest Annual Review of Genomics and Human Genetics is now online 🧬 Most read article so far is "Mechanisms of Enhancer-Mediated Gene Activation in the Context of the 3D Genome" @akispapantonis.bsky.social @mariekeoudelaar.bsky.social Check it out arevie.ws/47BZEJp Full TOC: arevie.ws/4plCaPe
- Reposted by Ufuk GünesdoganThe community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
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- Reposted by Ufuk GünesdoganNew paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
- Reposted by Ufuk GünesdoganExcited to share our new study in @cp-devcell.bsky.social dissecting how the brain-associated transcription factor OTX2 drives anteriorization of the mammalian gut by enhancer remodeling using stem cell-based models. #development #enhancers #patterning #stemcells www.cell.com/developmenta...
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- Reposted by Ufuk GünesdoganExcited to share the latest work from the lab led by @eharo84.bsky.social, in which we have used synthetic biology to explore the mechanisms by which different types of long-range enhancers ensure robust and precise developmental gene expression www.biorxiv.org/content/10.1...
- Reposted by Ufuk Günesdogan🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
- Reposted by Ufuk GünesdoganCheck out this exciting meeting and register! Fantastic line-up of speakers on cell biology of the nucleus and a great venue 🔥
- 📢 Abstract submission deadline reminder for 'Cell biology of the nucleus'! Before packing your bags and leaving for your summer vacation, there is one important task left to do: submit your abstract for #EESNucleus ✍️ Deadline is 26 August: s.embl.org/ees25-07-bl
- Reposted by Ufuk GünesdoganTo all post-docs: The Genome Biology dept @embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
- Delighted to see this work published! Congrats to Chris Todd and everyone involved - happy to have been part of the team.
- 🚨 New paper alert 🚨 I am excited to share our new work on epigenetic enhancer priming in early mammalian development genomebiology.biomedcentral.com/articles/10.... Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd. Short 🧵
- Reposted by Ufuk GünesdoganSave the Date! Development has teamed up with the Wellcome-funded consortium the Human Developmental Biology Initiative to co-organise a meeting on #HumanDevelopment. 📅7 - 9 Sep 2026 📍University of Warwick, UK Register your interest for #HumanDev26: www.biologists.com/meetings/dev...
- Reposted by Ufuk GünesdoganPlease pread the word. We have just launched the Hubrecht International PhD Program (HIPP). Are you looking for a PhD position in molecular and developmental biology or related subject in an international, very supportive and collaborative environment? Then apply to the HIPP!! 👇
- 🧬 Looking for a PhD position in molecular or developmental biology? 🔬 ✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
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- Reposted by Ufuk GünesdoganOur paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/
- Reposted by Ufuk Günesdogan⚠️ I am really excited to share the work of Anastasios Balaskas, an excellent PhD candidate in the lab, with the wider world. Tasos made a significant advance: generating a stem cell-based embryo model that contains both posterior and anterior neural tissues of the late-stage gastrulating embryo.
- Reposted by Ufuk Günesdogan🌟Congratulations to Azim Surani @gurdoninstitute.bsky.social @cam.ac.uk for receiving the 2025 Kyoto Prize - Basic Sciences. Azim's research fundamentally advanced our understanding of developmental biology🔬🧬 www.gurdon.cam.ac.uk/kyoto-prize-... #KyotoPrize #AzimSurani #DevelopmentalBiology
- Reposted by Ufuk GünesdoganOur review on ➡️"Histone modifications in development" is out 🍾 in 🔖 Development @dev-journal.bsky.social urnal.bsky.social Read more about histone tail and globular domain modifications during development: journals.biologists.com/dev/article/...
- Histone modifications in development Read this 'Development at a Glance' article by Yu-Hao Liu and @robertife.bsky.social, summarising the role of selected histone modifications during development. journals.biologists.com/dev/article/...
- Reposted by Ufuk GünesdoganThis is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u A short thread follows 1/n
- Reposted by Ufuk GünesdoganTextbooks: “Enhancers are just a bunch of TFBSs” But how do they REALLY work? New paper with many contributors here @berkeleylab.lbl.gov, @anshulkundaje.bsky.social, @anusri.bsky.social A 🧵 (1/n) Free access link: rdcu.be/erD22
- Reposted by Ufuk GünesdoganJoin us next Wed, for three amazing ECR researchers_ @fueyoraquel.bsky.social, @kaiamattioli.bsky.social and Laura talk about their work in #FragileNucleosome seminar series! In case you haven't joined any of the previous 2025 sessions, here is registration link: us06web.zoom.us/webinar/regi...
- Reposted by Ufuk GünesdoganCalling all European #Drosophila labs. Time for all of us, that are able, to step up to support FlyBase during this funding crisis.
- Reposted by Ufuk GünesdoganReally looking forward to @radaiglesiaslab.bsky.social's talk on "Gaining mechanistic insights into long-range gene regulation through synthetic biology approaches" in @enhancedgenomics.bsky.social's seminar series. 📅 June 5th 2025 tomorrow ⏰ 4pm GMT Please join us: us02web.zoom.us/webinar/regi...
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- 🚨Preprint alert!🚨 Great collaboration with the lab of Stefan Schoenfelder @stefanschoenfelder.bsky.social - we dissect the role of non-canonical enhancers in human pluripotent stem cells. 👇
- Delighted & excited to share our latest preprint on non-canonical enhancers in human pluripotent stem cells, the result of a fantastic and fun collaboration with @guenesdoganlab.bsky.social: www.biorxiv.org/content/10.1... 🧵 below
- Reposted by Ufuk GünesdoganHow to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...
- Reposted by Ufuk GünesdoganJoin our team as a postdoc and explore the exciting world of transposable elements and developmental biology with us! @imbavienna.bsky.social @vbcscitraining.bsky.social
- Come and join us if you are in Münster on Thursday!
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- Reposted by Ufuk Günesdogan📢 Have you registered for 'Gene regulation: one molecule at a time' yet? Submit your abstract by 8 April! 👉🏼 s.embl.org/grg25-01-bl #EMBLSingleMolecule will bring together single molecule genomics and imaging to study mechanisms across the central dogma at molecular resolution 🧬🔍
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- 🚨Exciting lecture alert!🚨 If you're in Göttingen on Feb 19 at 1:15 PM, don’t miss this year’s Ernst Caspari Lecture by Meritxell Huch @merihuchlab.bsky.social from MPI Dresden @mpicbg.bsky.social - join us for an inspiring talk!
