In this study, Bhakta Prasad Gaire, Yosef Koronyo, Jean-Philippe Vit, et al. show Chlamydia pneumoniae can reach retina & trigger immune responses linked to inflammation, nerve cell death & cognitive decline.
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Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina - Nature Communications
This study detects Chlamydia pneumoniae in human retina and brain, increasing with AD severity. Retinal pathogen load with Aβ42 may predict AD stage. In models, infection drives Aβ deposition and NLRP...
