Giulio Maria Pasinetti, MD, PhD

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  Giulio Maria Pasinetti, MD, PhD giuliompasinetti.bsky.social · Feb 5
  In this study, Bhakta Prasad Gaire, Yosef Koronyo, Jean-Philippe Vit, et al. show Chlamydia pneumoniae can reach retina & trigger immune responses linked to inflammation, nerve cell death & cognitive decline. @cedarssinaihsu.bsky.social @natureportfolio.nature.com 👉 www.nature.com/articles/s41...
  

  Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina - Nature Communications

  This study detects Chlamydia pneumoniae in human retina and brain, increasing with AD severity. Retinal pathogen load with Aβ42 may predict AD stage. In models, infection drives Aβ deposition and NLRP...

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  Giulio Maria Pasinetti, MD, PhD giuliompasinetti.bsky.social · Feb 4
  Alison Warren, @phdleigh.bsky.social, et al.'s new, scoping review is shedding light on the growing evidence that #Gut #Microbiome imbalances may play a key role in development & progression of #MCI & #Alzheimers. @alzdemjournals.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
  

  The microbiota–gut–brain axis in mild cognitive impairment and Alzheimer's disease: a scoping review of human studies

  Alzheimer's disease (AD) is projected to become the highest-burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut micr...

  alz-journals.onlinelibrary.wiley.com
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  Giulio Maria Pasinetti, MD, PhD giuliompasinetti.bsky.social · Feb 2
  Here, researchers Sarah Shipley, Caswell Barry, et al. investigated how disruptions in hippocampal reactivations relate to place cell stability and spatial memory deficits in #AlzheimersDisease mouse model. @ucl.ac.uk @currentbiology.bsky.social @cellpress.bsky.social 👉 www.cell.com/current-biol...
  
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  Giulio Maria Pasinetti, MD, PhD giuliompasinetti.bsky.social · Jan 30
  In this study, researchers Rachael Layden, Jenna Groh, Annalise Miner, et al. examined the independent contribution of #CTE neuropathology w/ #Dementia & cognitive symptoms. @alzdemjournals.bsky.social @alzassociation.bsky.social 👉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
  
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