Andres Hidalgo
- I am excited to share our new paper @JExpMed led by our one and only #Alejandra_Aroca
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- What are #Neutrophils? why are there so many? how are they shaped by disease? how is it that they maintain memory despite their short lifespan? Our views on this and much more written with #Ivan_Ballesteros for @cp-cell.bsky.social 👇 authors.elsevier.com/a/1mFj9L7PXu...
- Spoiler: We model the power of neutrophils as a reflection of their Collective behavior. Yes, just like insects… they become powerful. Here’s an idea of how this works
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- Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils "interpret" physiology.
- I’m thrilled to introduce you to the NeuMap! our latest work in@nature.com. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour de force www.nature.com/articles/s41...
- Kudos to the wonderful people in our labs who made this possible @dcerezowallis.bsky.social #andrea_rubio #ivanbamartin #LaiguanNg and to the many collaborators who helped us along the way and many many others. Science is a team sport.
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- Here is a full-text access to a view-only version of the paper: rdcu.be/eM7xA
- NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM #structuralimmunity #immunosky
- Thank you to our editor, Kirsty Minton, and the staff at NRI for the opportunity to share our thoughts on this emerging topic.
- NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM #structuralimmunity #immunosky
- Immune cells are more than aggressors; they are also diplomats that prevent conflict by improving the barrier capacity, the ECM, and the mechanical properties of tissues. We are just beginning to scratch the true impact of immune cells on tissues and overall organismal physiology.
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- Reposted by Andres HidalgoNature research paper: Matrix-producing neutrophils populate and shield the skin go.nature.com/4iJSgy5