Thilo Muth
Group Leader and Adjunct Professor 🧑🏫 | Public Health | Data Engineering & Visualization | 🧬 Bioinformatics & 📈 Mass Spec Enthusiast | 📍 Berlin | Passionate About Collaboration and Open Science 🔬✨
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- We are happy to share that the preprint for Proteobench is available now on biorxiv! Check it out here: www.biorxiv.org/content/10.6... Congratulations and thanks to everyone involved for the great effort!
- New preprint! 🚀 We introduce AbTags – antibody–peptide fusion proteins that massively amplify signal, enable absolute quantification of binding events, and are read out together with the single-cell proteome by LC–MS. AbTag platform is patent-pending. Preprint: www.biorxiv.org/content/10.6...
- ✨New preprint! 🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al! Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬 🔗👇
- Out today in Science Magazine — First author Veronika Kivenson and PIs Jill Banfield (The Banfield Lab) and Alanna Schepartz team up to reveal a new genetic code in #archaea, with implications for #methane and #climate, and #bioengineering! Learn more: ow.ly/Kuem50Xurh0
- Super excited to have this paper out. We developed a complex set of ground truth samples to test more than 110 statistical approaches for differential #metaproteomics We can now give clear guidance on what tests perform well. Thank you Tjorven Hinzke and @benoitkunath.bsky.social for the leadership
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- From @science.org Breakthrough of the Year: Solar Energy
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- The solution is right above us. Solar panels on existing buildings, car parks, and along highways generate clean power without sacrificing farmland or wild spaces. Let's use our built world first. #Renewables #Innovation
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- Das RKI-Impfquoten-Monitoring: Jedes Jahr werden die Impfquoten für alle Impfungen berechnet, die von der #STIKO für Kinder, Jugendliche, Erwachsene und Schwangere empfohlen werden. Im #EpidBull 50/25 wurden diese jetzt veröffentlicht. 👉 www.rki.de/DE/Aktuelles...
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- The #ASBMB26 symposium on single-cell proteomics also features: • Bogdan Budnik, @wyssinstitute.bsky.social • James Kostas, @princeton.edu • Jennifer Van Eyk, Cedars-Sinai ➡️Details: www.asbmb.org/annual-meeti.... #MakeItPossible #MolCellProt (@asbmbjournals.bsky.social)
- Single-cell proteomics is revolutionizing biology by measuring proteins in individual cells in real time. Join Ileana Cristea for this #MolCellProt symposium at #ASBMB26: www.asbmb.org/annual... ☑️ Late-breaking abstracts open soon — submit by Jan. 15: l.feathr.co/ESm5YGn8....
- Researchers have performed a large-scale genetic screen to uncover the hidden roles of #microproteins. One of the discovered microproteins, named PIPPI, was found to protect cells from stress in the endoplasmic reticulum. Published in @narjournal.bsky.social 🧪 #proteomics news.ki.se/new-micropro...
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- Cannot hide my joy, relief, excitement being able to share the outcome of persevering (to say the least) collaborative work. So... the MS glyco(proteomics) guidelines are published!! www.mcponline.org/article/S153... Many thanks to @beilstein-institut.bsky.social @glycosmos.bsky.social @sib.swiss
- It’s the first time that proteomics has been used to analyze Renaissance recipes. The project demonstrates an innovative way to study medicine and the circulation and use of medical recipes from the past. cen.acs.org/analytical-c... #chemsky 🧪
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- This project started 5 years ago. It led us to add isotope-labeling support to #FragPipe/#IonQuant. Since then, the tools have grown so much and are now widely used in #Chemoproteomics. Huge thanks to everyone, and special thanks to @stephanhacker2.bsky.social and @pzanon.bsky.social
- How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid? Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7) www.nature.com/articles/s41...
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- #Palaeoproteomics of Middle and Late Pleistocene hominin fossils and associated zooarchaeological assemblages from Central Eurasia with @fridowelker.bsky.social! Postdoc: jobportal.ku.dk/videnskabeli... Research Assistant: jobportal.ku.dk/videnskabeli...
- Thinking only of Rosalind Franklin today, and what was stolen from her (and so many other female scientists alongside her).
- On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...
- The US is the world's largest oil and gas producer. Yet, "China is now making more money from exporting green technology than America makes from exporting fossil fuels."
- I think about this post every day 🧪
- Strain displacement in microbiomes via ecological competition Cool @natmicrobiol.nature.com publication by @erikbakkeren.bsky.social @vit-pi.bsky.social @meganleeny.bsky.social @microscape.bsky.social & Kevin Foster www.nature.com/articles/s41...
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- A previously uncharacterized microbial enzyme is responsible for the production of molecular hydrogen in the gut, which drives the growth of other bacteria and has implications for human health, according to a paper in Nature Microbiology. go.nature.com/4oKOveG #microbiome #medsky 🧪
- 🧬 Thrilled to share our latest paper in @natmicrobiol.nature.com 📄 A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think. Our at-scale AI structure prediction gave a complementary perspective on viral evolution. www.nature.com/articles/s41...
- In a Consensus Statement in Nature Microbiology, a consortium of #microbiome scientists discusses current sequencing data sharing policies and proposes the use of a Data Reuse Information tag to promote equitable and collaborative data sharing. go.nature.com/4o1Gl1f 🧪
- You know what? There's actually a tested solution to this! it is brilliantly simple, and it WORKS. I would love to see @bsky.app and @support.bsky.team test this out. www.ucl.ac.uk/news/2023/ju...
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- Our latest paper introduces new methods for improving peptide retention time predictions in proteomics, incorporating chemical structure information to better handle unseen modifications. Read all about it in our preprint by👉 doi.org/10.1101/2025... #Proteomics #AI #MachineLearning
- If you are interested in mRNA vaccines against bacteria, take a look at our recent review. It was a pleasure to write this together with all co-authors! rdcu.be/eyjBq www.nature.com/articles/s41...
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