Mass Lab
Based @LIMES Institute @University of Bonn, researching developmental immunology. We ❤️ macrophages!
- Reposted by Mass Lab🧠 #ScienceSnack: The human brain must be able to link memories to their circumstances. Bonn Researchers have discovered two different neuron groups our brain uses to store content and context separately. Findings have been published in @nature.com. www.uni-bonn.de/en/news/004-... © UKB/A. Winkler
- Reposted by Mass LabCongratulations to Drs. Jose Villadangos and Hamish McWilliam's (@hay-mish.bsky.social) labs on their @science.org paper! Their teams at the Doherty Institute showed that #macrophages are key for MR1 antigen presentation and MAIT cell immunity. 🗒️ bit.ly/49W1GW1 🎤 bit.ly/44Ay1OG
- Reposted by Mass Lab
🚨 Postdoctoral Opportunity for Female Scientists🚨 The University of Vienna is awarding at least 20 fully funded 4 year postdoctoral positions to outstanding female scientists Interested? Get in touch via direct message careers.univie.ac.at/en/postdoc/e... #MicroSky 🧪 #PostDoc @univie.ac.at - 🧬🍽️ Your macrophages may be carrying your mother’s metabolic history! In our @cp-trendsimmuno.bsky.social article, we discuss how maternal diet programs lifelong immune function. authors.elsevier.com/sd/article/S... #ImmuneMemory #Macrophages #MaternalNutrition #DOHaD #EarlyLifeProgramming
- Reposted by Mass LabFresh from Elvira Mass Lab @masslab.bsky.social. We are happy to share our thoughts on how maternal malnutrition can shape the development of offspring tissue-resident macrophages during early development. Happy reading!
- Maternal diet shapes the development and identity of tissue-resident macrophages #immunology
- Reposted by Mass Lab#Microglia and CD8⁺ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15. From Frolov, @haohuang0086.bsky.social, Stumm, @masslab.bsky.social, Beyer et al.: rupress.org/jem/article/... 📘 In our #Neuroscience collection: rupress.org/jem/collecti... #SfN25
- Happy to have contributed to this beautiful story on #macrophage #development in mice and in #iPSC derived cells. www.science.org/doi/10.1126/... Big congrats to first author Tomi Lazarov for this massive work!!!!👏
- Interested in #macrophages? Don't forget the check out this Seminar Series 👇
- WE ARE BACK FROM SUMMER BREAK for our next #MagNet #Seminar ⏰Monday, Oct 13th, 4 pm (CET) 🧑🔬Thomas Marichal 🗣️“Decoding the lung macrophage landscape: trajectories, niches and functions in health and disease" see poster and webpage for the #zoom link: macrophagenetwork.com/magnet-semin...
- Reposted by Mass LabThe Vienna BioCenter PhD Program application deadline is approaching: October 10! Join one of Europe’s premier life science campuses, home to cutting-edge research across all areas of biology. Apply and start your scientific journey in Vienna! training.vbc.ac.at/phd-program/ #PhD #LifeSciences
- Love RNA biology? Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇). PhD student/postdoc position co-supervised by Clemens Plaschka & myself. DM or email us if you’d like to know more! @vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social
- Reposted by Mass Lab🔔PhD position open. Interested in building competencies in computational biology in spatial transcriptomics? Malte Luecken's lab and I have an open PhD position, part of the Munich School of Data Science. Application deadline: Sept 26 Link: www.mu-ds.de
- Reposted by Mass LabHad the wonderful opportunity to present our data on the effect of microplastics on macrophages at #EMDS2025 ! Such a beautiful venue 🤩 @masslab.bsky.social
- Reposted by Mass LabApplication is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
- Reposted by Mass Lab🚨 New in The EMBO Journal! Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins. 🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social 📄 www.embopress.org/doi/full/10....
- Reposted by Mass LabCome be my colleague! We have three open positions at the Assistant/Associate Professor level for candidates in all areas of the biological sciences. www.imperial.ac.uk/jobs/search-...
- Reposted by Mass Lab#WomenInSTEM becoming independent: People should feel free to be themselves and do great science. We asked ten women researchers about their science and the process of setting up a lab as an independent researcher: rupress.org/jem/article/...
- Reposted by Mass LabOut today! www.science.org/doi/10.1126/... From @kknoop.bsky.social & myself on early life immune development & the beautiful publication from Megan Koch & M Shenoy www.science.org/doi/10.1126/... Take home message: timing of early life exposures, milk IgG here, is critical for immune development.
- Reposted by Mass LabThis week's @science.org #IMMUNOLOGY-themed SPECIAL ISSUE features Reviews by {Kassiotis & Stoye}, {Nahrendorf, Ginhoux, & Swirski}, {Sharma, Gibbons, & Saphire}, & {@jessmetcalf.bsky.social, @grahammunology.bsky.social, Yates, & Cummings} + an absolutely wild & wonderful cover! scim.ag/3UqRrA6
- Reposted by Mass LabOur recent overview of human stem cell models for studying neuropsychiatric disorders (including their limitations and future directions) is now openly available @annualreviews.bsky.social of Neuroscience With the great @rebeccalevymdphd.bsky.social
- 🧠 New book chapter out! We review the developmental origin and functional diversity of #microglia - key players at the crossroads of #immunity and #neurodevelopment. 🔹 Ontogeny & specialization 🔹 Transcriptional & metabolic shifts 🔹 Roles in disease & repair 👉 authors.elsevier.com/a/1lKxcErwXf...
- Microglia and CNS macrophages are multifaceted cells! We are excited to share our published chapter in Advances in Immunology. If you are curious about where these cells come from and what roles they play; you can access it here: lnkd.in/egqqUYQT Link valid until August 16! @masslab.bsky.social
- 1/ 💡We are excited to share our latest paper, continuing our exploration of how maternal obesity programs offspring health via #macrophages - this time using #Drosophila as a model: shorturl.at/28tFo #MaternalObesity #Drosophila #Neurodegeneration #DOHaD #FlyResearch #MacrophageBiology
- 2/In this study, we uncover how maternal diet in flies(corresponding to maternal obesity in mammals) disrupts #neuronal integrity and #immune function in offspring. We identify axon #degeneration and shortened #lifespan, linking maternal overnutrition to long-term health consequences.
- 3/ This work builds on our previous findings published in @nature.com (Huang et al., 2025), where we showed that yolk sac-derived Kupffer cells mediate fetal liver programming in obese pregnancies, driving fatty liver disease in adulthood (www.nature.com/articles/s41...)
- 4/Together, these studies highlight the evolutionarily #conserved and multi-organ impact of maternal diet on offspring health and disease susceptibility. Huge thanks to Seyhmus Bayar and our collaborators for their fantastic work! @for5775.bsky.social
- Reposted by Mass Lab1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)
- Reposted by Mass LabThe fantastic Menon Lab (@madhvimenon.bsky.social) in the @lydiabeckeriii.bsky.social in Manchester are hiring!! 🚨DO NOT MISS YOUR CHANCE TO APPLY!🚨 www.jobs.manchester.ac.uk/Job/JobDetai... Postdoc seeking to unravel how lung-infiltrating #Bcells contribute to chronic lung disease #immunosky
- Reposted by Mass Lab🧪 One month until the application deadline. Get in touch if you are interested ⬇️ #immunosky #cardiosky #academicsky #ecr #studyintheuk
- We are SO EXCITED to share our story @nature.com: 🧵1/ Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring. This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease. 👉 Read here: rdcu.be/erD3b
- 2/ Kupffer cells are yolk sac–derived macrophages that colonize the fetal liver early in embryogenesis and play essential roles in metabolism and immune regulation. But what happens when their development is perturbed in utero by maternal obesity?
- 3/ Using a mouse model, we show that maternal obesity causes long-term transcriptional, metabolic & epigenetic changes in KCs. These reprogrammed KCs persist into adulthood and promote lipid accumulation in hepatocytes, leading to fatty liver disease (FLD).
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View full threadLed by @haohuang0086.bsky.social and Nora R. Balzer 📍 Developmental Biology of the Immune System, LIMES Institute #DOHaD #macrophages #FattyLiverDisease
- Reposted by Mass LabIt's time for our next #MagNet #Seminar! It's all about #KupfferCells and #KetogenicDiet presented by Gerasimos Anagnostopoulos via #Zoom ⏰ Monday, June 16th, 4 pm Visit our homepage for more infos: macrophagenetwork.com/magnet-semin...
- The #Rosshart Lab goes wild again! Ever wondered whether using #Wildlings in our research would change the outcome of our results? 🤔💡 #immunosky @fau.de www.nature.com/articles/s41...
- Super happy to be part of this initiative! Together with @agvazquez.bsky.social we will be working on the interaction between #Alveolar #Macrophages and #Epithelial #Cells in the #lung Still time left to apply!! www.linkedin.com/posts/elvira... #immunosky
- Proud to kick-off #HetCCI, a DFG-funded research consortium in Germany (Priority Programme #SPP2493 on heterotypic cell-cell interactions in epithelia). Follow us if interested in how epithelial cells interact with non-epithelial tissues in different settings! Webpage will follow asap. #cellbiology
- Reposted by Mass LabMeet our invited speakers!
- Reposted by Mass LabSpecial issue Immunometabolism and Beyond: from Liver to Brain! European Journal of Immunology Article types: reviews and research articles Submission deadline 1 November 2025 Thanks to Nadja, Matteo and Bin for this wonderful opportunity! #immunometabolism #EJI #CRC1292 #CRC355 #CRC156 #FZI
- Happy to be part of this initiative! The place to be in Germany for #immunologists !!! 😎
- Hurray! ImmunoSensation will go on! 🥳 The @dfg.de just announced that ImmunoSensation3, focussing on Immune Diversity will be funded! Let us #celebrate 7 more years of #immunology in #Bonn 🎉 www.immunosensation.de/news/immunos...
- Reposted by Mass LabWe are excellent! What a day - between hugs, applause and a lot of pride. Our rector? Jumping for joy. Our team? Overjoyed. Thank you to everyone who made this historic moment possible! @dependencybonn.de @immunosens.bsky.social @econtribute.bsky.social © V. Lannert/G. Hübl/Uni Bonn
- Reposted by Mass LabGrateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia
- Reposted by Mass Lab🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!
- Reposted by Mass Lab📢 We are #hiring a #PhD student to work on an interdisciplinary, collaborative project @dzne.science in Bonn, Germany! 🧠 If you’re interested in western diet-induced #neuroinflammation and innate immune signalling in #alzheimersdisease, check out our ad below 👇 jobs.dzne.de/en/jobs/1014...
- Just presented our story on #KupfferCells #liver & #microplastics togehter with @mariafviola.bsky.social in the basic science session @ #EASL2025 in #Amsterdam. Great format to promote ECRs and for fantastic discussions with scientists and clinicians!
- Reposted by Mass Lab#Microglia and CD8⁺ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15, say Aleksej Frolov, Hao Huang (@haohuang0086.bsky.social), Ralf Stumm, Elvira Mass (@masslab.bsky.social) Marc Beyer @dzne.science and colleagues: rupress.org/jem/article/... #omics #RareDisease
- Read our newest publication @jem.org about #microglia and #CD8Tcell interactions in spastic paraplegia! 💡Immune activation happens before #neuronal loss! 💡 Team effort with the labs of Marc Beyer and Ralf Stumm 👇 doi.org/10.1084/jem.... @limes-bonn.bsky.social @immunosens.bsky.social #immunosky
- First authors @haohuang0086.bsky.social and Aleksej Frolov made a terrific video summary 🎥 nextcloud.dzne.de/index.php/s/... @dzne.science
- Kati Mauel from our lab talking about splenic #macrophages and their response to #malaria infection at #EPW2025 🤩
- Full house at #EPW2925 in #phagocyte in motion session!
- Thanks to the organizers @sancholab.bsky.social @casanova-acebes.bsky.social & Carlos Silvestre for giving me the opportunity to kick-off this fantastic meeting #EPW2025 What a day for #macrophage lovers!
- #immunosky #epw2025 Great novel work by @masslab.bsky.social on the impact of micro and nanoplastics in macrophages! Large effect on liver Kupffer cells, while other organs are more protected. Read more here!!! sciety.org/articles/act...
- Reposted by Mass Lab#immunosky #epw2025 Great novel work by @masslab.bsky.social on the impact of micro and nanoplastics in macrophages! Large effect on liver Kupffer cells, while other organs are more protected. Read more here!!! sciety.org/articles/act...
- 1/ 🚨 New preprint alert! 🚨 Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
- 2/ 🧐 The big question: We know MNPs are in food and water, but how do they interact with our immune system and organs? Specifically, what happens when they accumulate in macrophages—the immune cells that regulate metabolism?
- 3/ 🔬 Using a chronic exposure model in mice, we found that liver-resident macrophages (Kupffer cells, KCs) are the primary site of MNP accumulation. Over time, this disrupts their function, leading to metabolic imbalances in the liver and beyond.
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View full thread9/ Let’s discuss! How concerned are you about plastic pollution and its impact on health? 🗣️ Drop your thoughts below! 👇 #Microplastics #Nanoplastics #ImmuneSystem #Metabolism #Science #Macrophages #KupfferCells
- We are thrilled to present our new story on #neonatal #liver #macrophages and how they crosstalk with #hepatocytes during this early stage of life 👇
- Kupffer cells control neonatal hepatic metabolism via Igf1 signaling biorxiv.org/content/10.1101/202…
- Reposted by Mass LabFirst Post on blue-sky. We are hiring! Post-doctoral position available in the neuroimmunology of stroke. Please check out link below and share elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
- Reposted by Mass LabJoint seminar by #DGfI Young Immunologists & Junge #GfV! 🎤 Topic: Preclinical & clinical development of novel anti-viral vaccines 🗓 Feb 24, 2025, 17:00 Register here! us06web.zoom.us/meeting/regi... #Immunology #VaccineResearch
- Reposted by Mass Lab#WeekendRead. #LiveForever. Lantz, Thorp &co show @cp-immunity.bsky.social that in neonatal, not adult, macrophages efferocytosis following heart injury leads to the production of throboxane, that acts on cardiomyocytes promoting proliferation & repair. #ScienceSavesLives
- Reposted by Mass LabSave the date for the GSCN #Conference on #stemcell #research and #translation in #Munich at @www.helmholtz-munich.de from 15 - 17 Oct 2025. Registration is open gscn-conferences.org/gscn-confere...
- Reposted by Mass LabCould bacterial translocation during colitis rewire the bone marrow? Check out our highlight of these cool findings by the Sancho lab ⬇️ authors.elsevier.com/a/1kbBf3qNrU... @masslab.bsky.social
- "Bacterial translocation promotes #trained #immunity" !!! 🤩 Check out our preview highlighting the beautiful peace @cp-immunity.bsky.social by the Sanches lab. With @mariafviola.bsky.social #macrophages #Mincle authors.elsevier.com/a/1kbBf3qNrU...
- sorry for the auto-correction mistake! Of course this is from the Sancho lab!!! @sancholab.bsky.social 😆
- Happy to have inspired our colleagues to study #hematopoiesis #yolksac =) Congrats to @wkolanus.bsky.social for this beautiful #developmental study!
- The authors report that Trim71-KO leads to decreased embryonic primitive erythropoiesis and impaired vascular development and provide evidence for direct repression of Eomes via Trim71-mediated mRNA binding @wkolanus.bsky.social buff.ly/3QaRM7y
- Reposted by Mass LabDelighted to start the new funding period of our #SFB1454! Can definitely recommend the exhibition @museumkoening, a must for everyone interested in healthy living and aging @dzne.science
- Application deadline extended to February 2nd! #PhD #macrophages
- Only few more days left to apply! We have several #PhD #positions in the field of #immunology #development #cellbiology #macrophages! #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/ Pls repost👇 #immunosky
- Reposted by Mass LabCome join us at the Becker! Our Deputy Cellular Immunology Branch Lead Dr Madhvi Menon has a fantastic Postdoc opportunity in her lab 👇 #ImmunoSky
- We are happy to announce the new @for5775.bsky.social seminar series. Watch out for fantastic #macrophage talks!
- Join our #MagNet #Seminar by Nicolas Venteclef! He will be talking about #epigenetics and #adipose tissue #macrophages: January 20th at 4pm CET. Enter #zoom via QR code
- Reposted by Mass LabHere is the new Research Unit on #macrophages ❤️ Apply to our projects! Deadline has been extended to February 2nd!
- Only few more days left to apply! We have several #PhD #positions in the field of #immunology #development #cellbiology #macrophages! #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/ Pls repost👇 #immunosky
- Only few more days left to apply! We have several #PhD #positions in the field of #immunology #development #cellbiology #macrophages! #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/ Pls repost👇 #immunosky
- Reposted by Mass LabWe will have upcoming vacancies in the Iden lab at Saarland University (PhD student, postdoc, technician). If you wish to join an international research team working on cell-cell communication in mammalian epithelia, contact me (please provide CV, motivation letter, contacts of 2-3 references).
- Reposted by Mass LabExcited to share our revised manuscript! We adapted new live imaging tools to track the same tissue resident macrophages for months in aging mice. We found a macrophage population that contributes to vascular health in young skin, but is lost as we age... www.biorxiv.org/content/10.1...
- Reposted by Mass Labby regulating blood and cerebrospinal fluid flow, and are implicated in neurodegenerative processes, including amyloid deposition and calcification… www.cell.com/trends/immun... @cellpress.bsky.social
- Are you looking for a #PhD position in the interdisciplinary field of #immunology #development #cellbiology? Do you love #macrophages? #FOR5775 is hiring!! Find details here: macrophagenetwork.com/news-2/ Pls repost👇 #immunosky
- Reposted by Mass LabNeue #DFG-Forschungsgruppe @unibonn.bsky.social @masslab.bsky.social untersucht die Rolle von #Makrophagen in der #Gewebeentwicklung: macrophagenetwork.com
- We are super happy that our #FOR5775 #MagNet got funded! 🥳 Thanks to @dfgpublic.bsky.social look out for interesting #macrophage science in the coming 4 years! www.dfg.de/de/service/p...
- Reposted by Mass LabStill one week to apply ! Join us as a Group Leader in Infection Biology at IPBS in Toulouse: We're looking for a dynamic leader with a keen interest in the cell biology of bacterial pathogens and antimicrobial immunity. Apply by December 10th. For more information 👇 www.ipbs.fr/the-ipbs-tou...
- Reposted by Mass Lab📢 PhD Alert! Join us for an exciting PhD project in gorgeous York 🧠 🔬 You will be based in the Hahnlab (sites.google.com/york.ac.uk/hah…) in gorgeous York & work with an interdisciplinary team of researchers. Happy to chat! Apply here: lnkd.in/es-nY8uD #PhDposition
- #macrophage #barcoding 🤯 Time to get rid of the "fetal liver monocyte" origin for resident macrophages?!? Congrats to the Rodewald lab for this work! www.biorxiv.org/content/10.1...
- Reposted by Mass Lab#WeekendRead #FungiPower! Liao Gao Iliev &co show @ Nature that the stomach of wild, not lab, mice is colonized by an immunosilent fungus! Mucus alterations via diet or antibiotics drive a Th2 -not Th17- response that worsens allergy but protects against parasites! doi.org/10.1038/s41586-024-08213-2
