Anukul Shenoy
Assistant Professor & Principal Investigator,
Shenoy Lab of Barrier Immunobiology (SLOBI),
Microbiology & Immunology | Pulmonary & Critical Care Medicine,
The University of Michigan- Ann Arbor
shenoy.lab.medicine.umich.edu
- Reposted by Anukul Shenoy[Not loaded yet]
- It was fun translating our research into a colorful, pre-college student friendly, and (most importantly) free & openly accessible education resource! I hope that our science & stories of our rising stars will inspire next-gen students into science!! @umichmicroimmuno.bsky.social
- In our latest collection of free education resources, we explore immunology with Dr @anukulshenoy.bsky.social. He is investigating how lung-resident T cells detect danger, remember past infections and protect us from infections. futurumcareers.com/breath-by-br...
- Reposted by Anukul Shenoywww.sciencedirect.com/science/arti... @anukulshenoy.bsky.social Using our model of neutrophilic asthma, we identify lung epithelial-CD4+ TRM cell crosstalk as a key rheostat of allergic airway neutrophilia.
- Reposted by Anukul Shenoywww.sciencedirect.com/science/arti... @anukulshenoy.bsky.social Using our model of neutrophilic asthma, we identify lung epithelial-CD4+ TRM cell crosstalk as a key rheostat of allergic airway neutrophilia.
- Reposted by Anukul Shenoy[Not loaded yet]
- Reposted by Anukul ShenoyLung CD4+ resident memory T cells use airway secretory cells to stimulate/regulate onset of allergic airway neutrophilic disease Cell Reports www.cell.com/cell-reports... @anukulshenoy.bsky.social We identify lung epithelial-CD4+ TRM cell crosstalk as a key rheostat of allergic airway neutrophilia.
- Reposted by Anukul ShenoyLung CD4+ resident memory T cells use airway secretory cells to stimulate/regulate onset of allergic airway neutrophilic disease Cell Reports www.cell.com/cell-reports... @anukulshenoy.bsky.social We identify lung epithelial-CD4+ TRM cell crosstalk as a key rheostat of allergic airway neutrophilia.
- We are so excited to share our recent work, which develops a novel, simple, and tractable model of allergic airways neutrophilic disease in mice. A 🧵 (1/n) www.cell.com/cell-reports...
- Neutrophilic asthma is a vexing disease due to its steroid-resistance. A barrier to mechanistic understanding and therapeutic development against this airway disease has been a lack of animal models. (2/n)
- Here, inspired by Lalit Beura's "wild vs lab mice" work @Dave Maopust's lab, we asked if repeated but transient airborne allergen exposure in SPF mice 🐭 would instill adult human like biology and mimic neutrophilic allergic airways disease in mice. Turns out, it does! (3/n)
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View full threadThis work took a village: Thanks Vijay, Filiz, Carolina and team for help with experiments. Thanks to collabs: Alan Fine, Josh Welch, Felicia Chen, Anna C Belkina, and most importantly my postdoc advisor and lifelong mentor, Jay Mizgerd for support towards this non-pneumonia story 😁! (n/n) 🍾🎉🥳
