Nate
PhD Candidate at Princeton University
Chemical and Biological Engineering Department
Biomolecular condensates, biophysics, and molecular simulations
Member of the Joseph Group (https://josephgroup.princeton.edu/)
Princeton '22-Present | Penn '18-'22
- Reposted by NateHow does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social
- I am very excited to share our pre-print that was just released on the bioRxiv entitled "Biomolecular Condensates Dictate the Folding Landscape of Proteins" doi.org/10.64898/202... Very grateful for @jerelleaj.bsky.social and the members of the Joseph Group for their support on this project! (1/4)
- I am very excited to share our pre-print that was just released on the bioRxiv entitled "Biomolecular Condensates Dictate the Folding Landscape of Proteins" doi.org/10.64898/202... Very grateful for @jerelleaj.bsky.social and the members of the Joseph Group for their support on this project! (1/4)
- Key aspects of our framework include that: 1. Condensates tune protein structure through both multivalent interactions (promotes unfolding) and crowding (promotes folding). 2. Kinetic transitions in protein structures are frustrated within condensates due to coupled conformational (2/4)
