Kevin Murach
Studying muscle in the Ozark mountains - M3R Lab. Bourbon aficionado. Amateur watch builder. Average exerciser. My wife says I’m a “six wing five”.
musclemasslab.uark.edu
- Reposted by Kevin MurachNice feature in @theatlantic.com by @bonnietsui.bsky.social Our lab’s latest study reveals that skeletal muscle doesn’t just remember growth- it also remembers inactivity. Repeated disuse leaves a molecular imprint that shapes future responses. www.theatlantic.com/health/2026/...
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- Reposted by Kevin MurachNice work and congrats @kevinmurachphd.bsky.social & colleagues for their new #SkeletalMuscle paper: Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle. #Myoblue tinyurl.com/3vhxwku4
- Upcoming Postdoc Position! With Chris Nelson’s lab at U of A, we are looking for a fully supported 2-year postdoc to work on muscle gene editing and detection of gene doping in vivo. If interested, email myself and Chris: kmurach@uark.edu and nelsonc@uark.edu #myoblue
- Reposted by Kevin MurachFirst post on Blue Sky New pre-print! Does muscle remember disuse muscle wasting? Our new study shows skeletal muscle retains a molecular memory of disuse! Young muscle shows transcriptional resilience to repeated atrophy. Aged muscle shows exaggerated susceptibility. doi.org/10.1101/2025...
- A heavy lift from a literal strongman, PhD candidate PJ Koopmans “The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus” 💪🏻 www.biorxiv.org/content/10.1...
- Some interesting data from postdoc Nate Serrano: “Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle” www.biorxiv.org/content/10.1...
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- Regenerate to “Rejuvenate”: Insights From Adult Resident Stem Cells of Aged Flatworms and Mice. A fun collaboration! onlinelibrary.wiley.com/doi/10.1111/...
- Final version in @pnasnexus.org “Satellite cells choreograph an immune cell-fibrogenic cell circuit during mechanical loading in geriatric skeletal muscle” academic.oup.com/pnasnexus/ar...
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- Prioritizing skeletal muscle health for successful aging “The beneficial effects of exercise on skeletal muscle cannot be overstated, and the impact of healthy skeletal muscle on successful aging should not be underestimated.” www.openaccessgovernment.org/article/prio...
- “Muscle memory theory: A critical evaluation” in @JPhysiol led by postdoc Nate Serrano physoc.onlinelibrary.wiley.com/doi/10.1113/...
- Our Special Issue is live in J Physiology! w/ @mvfranchi.bsky.social & Prof. Paul Greenhaff “Cardiac, skeletal muscle and neuromuscular plasticity in disuse and inactivity”. So many great contributions! Add it to your reading list #myotwitter physoc.onlinelibrary.wiley.com/toc/14697793...
- “Satellite cells choreograph an immune cell-fibrogenic cell circuit during mechanical loading in geriatric skeletal muscle” @myoblue.bsky.social @pnasnexus.org academic.oup.com/pnasnexus/ad...
- “Making Sense of MYC in Skeletal Muscle: Location, Duration, and Magnitude” journals.physiology.org/doi/abs/10.1...
- A tour de force! Mouse, worm, and human data all telling the same story. Amazing! “microRNA-1 Regulates Metabolic Flexibility by Programming Adult Skeletal Muscle Pyruvate Metabolism” www.sciencedirect.com/science/arti...
- Reposted by Kevin MurachRejuvenation in planarians. Check out the details in this link: www.nature.com/nataging?gcl... @nataging.nature.com
- Reposted by Kevin MurachOur latest review is out now in @jphysiol.bsky.social The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings Great team effort 🙌 @grithhojfeldt.bsky.social, Christian Hoegsbjerg, Arvind von Keudell @ismcopenhagen.bsky.social doi.org/10.1113/JP28...
- Reposted by Kevin MurachIf you too are experiencing mental health issues due to the ongoing shitshow, please DM me or Signal me at ziadadina.19, I am trying to build a community to help each other. Y'all, please repost and help me out, this is serious stuff
- Myocellular adaptations to short-term weighted wheel-running exercise are largely conserved during C26-tumour induction in male and female mice #myoblue physoc.onlinelibrary.wiley.com/doi/epdf/10....
- Final Version: “A history of omics discoveries reveals the correlates and mechanisms of loading-induced hypertrophy in adult skeletal muscle. 2024 CaMPS young investigator award invited review” #myoblue journals.physiology.org/doi/epdf/10....
- Chambers et al. “At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle” #myoblue onlinelibrary.wiley.com/doi/full/10....
- Seems to go along with recent work from @longhuaguo.bsky.social www.nature.com/articles/s43...
- Cool data here. We have some mouse data (regeneration, not amputation) that supports this! Stay tuned and great stuff @longhuaguo.bsky.social #myoblue @natureaging.bsky.social
- This was a real labor of love: “A History of Omics Discoveries Reveals the Correlates and Mechanisms of Loading-Induced Hypertrophy in Adult Skeletal Muscle” w/Toby Chambers. #myoblue journals.physiology.org/doi/abs/10.1...
- Reposted by Kevin MurachOur magnum opus on everything related to #aging is out as a preprint in Physiological Reviews @apspublications.bsky.social @apsphysiology.bsky.social #openaccess. Great collaboration with @regula-furrer.bsky.social @biozentrum.unibas.ch @unibas.ch. doi.org/10.1152/phys... Some teasers: 🧵 1/9
