Jeanine Gezelle
Columbia PhD candidate studying viral RNA structure and degradation
- Reposted by Jeanine GezellePreprint on the Stanford #RNA 3D folding Kaggle challenge is out. My scientific new year’s resolution is to brush up on template-based modeling. #gofai www.biorxiv.org/content/10.6...
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- Reposted by Jeanine Gezelle🔬 #Trypanosomes process their large rRNA in a highly unusual way-by cutting it into six pieces. A new study from @schneian.bsky.social lab identified two essential proteins, TbLrRP1 and TbLrRP2, that drive this process. Read more: doi.org/10.1093/nar/... #NARBreakthrough #RibosomeBiogenesis
- Reposted by Jeanine GezelleWith many postdoc grants like the NSF PRFB, Ford Fellowship, and Hanna H. Gray fellowships disappearing, I am currently looking for grants that could fund incoming postdoctoral scholars. Here is a thread of some of them 🧵
- Reposted by Jeanine GezelleMamdani: "New York will remain a city of immigrants, a city built by immigrants, powered by immigrants, and as of tonight, led by an immigrant."
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- Reposted by Jeanine GezelleToday is only the beginning. Our time has come, New York. Our time is now.
- Reposted by Jeanine GezelleExcited to announce the YAK lab's first paper and the discovery of the FIRST human cellular PRF signal to give access to two overlapping open reading frames (science.org/doi/10.1126/...)! Before we dive in, the story actually begins in a Nature from 11 years ago
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- Reposted by Jeanine GezelleNSF today released instructions for the next round of applicants to its Graduate Research Fellowship Program. A key group—second-year Ph.D. students—is no longer eligible, and students who are still able to apply will face an unusually narrow timeframe. scim.ag/3KlQkQk
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- Reposted by Jeanine GezellePlease share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment. The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP jasonjwilliamsny.github.io/grfp2025/
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- Reposted by Jeanine GezelleOur new pre-print from the Greenberg and Churchman labs shows that activity-dependent modulation of RNA stability is a major, and underappreciated, mechanism of gene regulation in neurons. Tutorial below! www.biorxiv.org/content/10.1... (1/11)
- Reposted by Jeanine GezelleBeen thinking about creating a collection of good protein structure figures, as inspiration for my own work. #1 www.nature.com/articles/s41...
- Our study from the Steckelberg lab is out now in @narjournal.bsky.social !! We dove into a new nuclease-blocking viral #RNA structure important for viral infection, which provided evidence of similar structure-based strategies across diverse viral families. academic.oup.com/nar/article/...
- Thank you to my PhD mentor @lenasteckelberg.bsky.social and all authors who made the work possible: @sophiekorn.bsky.social, Jayden McDonald, Zhen Gong, Anna Erickson, Chih-Hung Huang, Feiyue Yang, Matt Cronin, Yen-Wen Kuo, and Brian Wimberly
- Reposted by Jeanine GezelleI am so incredibly excited to share our latest work, on the exploration of #RNA secondary structure ensembles and discovery of RNA regulatory structural switches in bacteria and human cells, just out in @natbiotech.nature.com: nature.com/articles/s41.... A short tread! (1/n)
- Reposted by Jeanine GezelleNew paper: More than 2700 human 3′UTRs are highly conserved. These 3′UTRs are essential components in mRNA templates, as their deletion decreases protein activity without changing protein abundance. Highly conserved 3′UTRs help the folding of proteins with long IDRs. www.biorxiv.org/content/10.1...
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- Reposted by Jeanine GezelleIdentified in the 1970s, the precise molecular function of the alternative initiation factor eIF2A has remained unclear. Here, we map its interactome and uncover a surprising role in ribosome-associated quality control (RQC) upon ribosome stalling. 1/x www.biorxiv.org/content/10.1...
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- Reposted by Jeanine GezelleNucleic acid structural biologists expose that many CASP16 predictions, even ones obtaining high scores by CASP metrics, are inaccurate in the most functionally relevant regions! Read more insights on functionally relevant features by the expert structure determiners (doi.org/10.1101/2025...).
- Reposted by Jeanine GezelleThis is just an excellent preprint by Rasmus Jensen and colleagues from Julia Mahamid's lab @embl.org - a tour de force of Cryogenic electron tomography to do in cell structural biology in which they discover a new complex and solve its structure and function! www.biorxiv.org/content/10.1...
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- Hey #RNAsky check out our new preprint! we solved a new nuclease-blocking viral #RNA structure and found some illuminating similarities across diverse viral families. Thread below ⬇️ biorxiv.org/content/10.110…
- Hi Bluesky, just in time for the holidays I am excited to share the latest pre-print from my group! We solved the 3D structure of a mysterious viral RNA that resists degradation by host nucleases. A short 🧵 &link below – please also check out the full video! #RNA #RNAbiology #RNASky #lovevirology
- Reposted by Jeanine GezelleAmazing work revealing the mechanisms by which mRNAs are delivered to the bacterial ribosome! 🤯 Congrats to the Weixlbaumer lab and their collaborators in the Walter and Rappsilber labs! 🍾
