Jacques Fattaccioli
Microfluidics • Soft matter • Cells
Ass. Pr. at Sorbonne U. / ENS-PSL and IPGG
Maker of chips, droplets, and tools for curious biology.
Homepage : https://fattaccioli.github.io
- Reposted by Jacques Fattaccioli
- @espciparispsl.bsky.social a nice view from rue Vauquelin !
- Today Estelle LU from our team defended her PhD thesis on the "Microfluidic Fabrication and Characterization of AESO microparticules" in front of P. Joseph (LAAS), V. Schmitt (CRPP) and R. Bongiovanni (Politechnico Torino). Congratulations Dr Lu !
- Reposted by Jacques FattaccioliHappy to share that I will be presenting at #CellBio2025 this afternoon during the #CSCB session in room 108 our work on #phagocytosis by #macrophages mannose receptor done @institutcochin.bsky.social by @chiarapompili.bsky.social with @jfattaccioli.bsky.social and @jean-Maurice Mallet
- Reposted by Jacques Fattaccioli#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.
- Reposted by Jacques Fattaccioli
- Reposted by Jacques Fattaccioli
- We introduce a modular biosensing strategy using targeted lipid microparticles to monitor phagosomal acidification in real time. These biomimetic particles are engineered to couple receptor-specific uptake with fluorescence-based pH reporting in macrophages. www.biorxiv.org/content/10.1...
- Each particle carries pH-responsive BODIPY dyes on its surface and a stable reference probe in the core, enabling ratiometric readouts. By decorating the membrane with Fcγ-binding ligands, we drive controlled uptake and capture the earliest steps of phagosome formation.
- Inside macrophages, the particles report the onset and progression of phagosomal acidification at single-object resolution. This work is a collaboration with B. Dumat and J.M. Mallet (ENS-PSL, Chemistry Dpt) and @florenceniedergang.bsky.social (Institut Cochin)
- We introduce a microfluidic device that can trap, analyze, and release individual microparticles on demand using membrane deformation driven by pneumatic pressure. The setup uses a deformable membrane suspended over an array of traps. www.sciencedirect.com/science/arti...
- Confocal measurements reveal clear pressure-dependent deformation profiles, in excellent agreement with a thick-membrane model. Controlled fluidic and pneumatic actuation enables rapid, fully reversible trapping within seconds.
- We also built a Python/μManager interface that automates trapping, imaging, motion control, and bubble-free priming steps. The result is a robust, fully automated platform for high-throughput single-object studies, from screening assays to mechanobiology and dynamic imaging workflows.
- A collaboration between Alexandre Chargueraud, graduate student in our team (fattaccioli.github.io) and Lars Kool from the IPGG Microfabrication facility (www.plateformeipgg.fr). This work has been presented at the Micro and Nano Engineering (MNE) conference in 2024.
- Reposted by Jacques FattaccioliOur work on hydrodynamic instabilities in active jets is on the cover of PRL this week! journals.aps.org/prl/abstract... A dialogue between experiment and theory, where we use light to control active suspensions and show how they can be destabilized by their self-generated flows
- Reposted by Jacques Fattaccioli#FDS2025 : @institutcochin.bsky.social a reçu dans ses laboratoires, 140 collégiens et lycéens. 11 équipes de recherche ou plateformes technologiques ont fait découvrir aux élèves la démarche scientifique et la recherche biomédicale. @cnrsbiologie.bsky.social @inserm.fr @upcite.bsky.social
- Reposted by Jacques FattaccioliThank you @cellmech2025.bsky.social for the invitation, great science, great people, great community!
- What an interesting talk!! Thank you so much, @memilieterret.bsky.social! #cellmech2025
- A nice sky viewing night with family and kids, thanks to the Space Bus, in Corsica and under the full moon. Discovered these new (?) smart telescopes providing easy imaging of celestial bodies for a reasonable price
- Reposted by Jacques FattaccioliFirst post in the Bsky-sphere! You’ll find info about my scientific activity, the DyCRIC team bit.ly/4lgSHk8, and @institutcochin.bsky.social !
- Reposted by Jacques FattaccioliA condensate-based approach reversibly sequesters lipid droplets (LDs) in cells, temporarily halting their functions and enabling detailed study of LD biology and the interactions of LDs with other cellular structures www.nature.com/articles/s41...
- Reposted by Jacques FattaccioliWhat if we could trap Lipid Droplets and control their dynamics in cells? Our latest work does just that, using Engineered Condensates to manipulate LD behavior. Exciting results by Chems Amari and the team! Great collab with @abdourachidthiam.bsky.social #Organelles #Condensates rdcu.be/emYpU
- J'ai deux tickets pour Shed Seven à la Maroquinerie le 2/5/2025. Pour les nostalgiques Britpop des 90's. Revente prix coûtant.
- Reposted by Jacques Fattaccioli[Not loaded yet]
- Reposted by Jacques Fattaccioli[Not loaded yet]
- Reposted by Jacques FattaccioliC'est parti pour la finale du concours "Ma thèse en 180 secondes" de Sorbonne Université ! 🙌 👉 RDV à partir de 18h en direct sur YouTube pour encourager nos doctorantes et doctorants : www.youtube.com/watch?v=Eqhi... #MT180 - @mt180fr.bsky.social
- Reposted by Jacques FattaccioliOn Feb 11, we celebrate the International Day of Women and Girls in Science. @institutcochin.bsky.social exhibits gender equality among directions and team leaders and recruits young women with exceptional talent, among them in 2024 Clotilde Cadart: institutcochin.fr/en/news/inte... #WomenInScience
- Reposted by Jacques FattaccioliSaviez-vous que de nombreuses plateformes de l'Université PSL sont ouvertes aux industriels ? 1re Journée de l’Innovation en Santé du Pôle PSL Innovation, sur le thème Biothérapies & Bioproduction 19 novembre 9h30-19h30 app.swapcard.com/event/journe... avec @jfattaccioli.bsky.social #ESPCIAlum
