Bethan Lloyd-Lewis
Wellcome Trust Research Fellow, University of Bristol. Epithelial cell fate dynamics during tissue development and cancer. #stemcells #devbio #mammarygland #morphogenesis #microscopy #breastcancer. She/her.
- Reposted by Bethan Lloyd-LewisHelpful update into UKRI and research council funding changes from Zoe Kleinman @zsk.bsky.social But please more focus on 2 things... 1) Immediate effects (eg funding decisions expected in March) 2) Likely disproportionate effects on early career scientists www.bbc.co.uk/news/article...
- Reposted by Bethan Lloyd-LewisI think Ian Chapman's focus throughout this process has been excessively PI-centred and ignores early career researchers and training. A big funding pause doesn't cause them to worry about their jobs. It causes them to lose their jobs. And to be unable to get new ones. Their careers will be ended.
- Reposted by Bethan Lloyd-Lewis🚨 New preprint! We built a single-cell atlas of 14 multilayered epithelia and revealed a conserved transcriptomic program guiding tissue architecture and fate composition. Our work brings decades of tissue-specific studies together into a unified evo-devo framework. www.biorxiv.org/content/10.1...
- Reposted by Bethan Lloyd-LewisAdd our first pre-print to your reading list? Using AF2 and MD, we've characterised structures and conformational ensembles of human rhomboid proteases - and revealed some surprises along the way. Feel v.lucky to work alongside Bryony & @robincorey.bsky.social! Please share: tinyurl.com/3h8r7f5y
- Reposted by Bethan Lloyd-LewisReally happy to share a link to our work showing that anti-progestin therapy could help prevent breast cancer before menopause. Published today in Nature, the study suggests this could be a new way to stop breast cancer before it starts: urldefense.com/v3/__https:/... Brilliant team science
- Reposted by Bethan Lloyd-LewisThis was a fun chat. Thanks @jcellsci.bsky.social for featuring me and spotlighting our work. Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13.... We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.
- One of the ‘Cell Scientists to Watch’ from our #JCSciliaSI is Girish Ram Mali @dyneinassembly.bsky.social @dunnschool.bsky.social. In this interview we learn about Girish’s career path, scientific mentorship, and how science is a human endeavour. journals.biologists.com/jcs/article/...
- Reposted by Bethan Lloyd-LewisEver wondered how adult organs preserve epithelial barrier integrity while continuously exposed to mechanical stress? We tackled this question in our new preprint – led by our brilliant PhD student Vishnu Krishnakumar! (1/11) 🔗 www.biorxiv.org/content/10.1...
- Reposted by Bethan Lloyd-LewisThis week has been special for us, marking 100 years of supporting biologists and inspiring biology. We celebrated our achievements at @zoologymuseum.bsky.social last night. We want to thank all our staff, whose continual inspiration and daily support for one another make our work possible.
- Reposted by Bethan Lloyd-LewisVery sad news, John Gurdon has died. A developmental biologist's developmental biologist, Nobel prize winner His work is the foundation of much of today's dev & stem cell bio. An inspiration to many, including me. Always asking questions & wanting the answers www.magd.cam.ac.uk/news/profess...
- Reposted by Bethan Lloyd-LewisThrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️
- Reposted by Bethan Lloyd-LewisI’m looking for a Postdoc to join my new lab @pdncambridge.bsky.social on an MRC-funded project and explore maternal inter-organ communication with a focus on the mammary gland, using a novel mouse model. 📍 Tenure: 3 years ⏳ Deadline: 15 August 2025 Please RT 🙏 👉 www.jobs.cam.ac.uk/job/51984/
- Reposted by Bethan Lloyd-LewisFantastic opportunity to start your independent career at the JIC here. Great startup package. Repost = nice. Thank you!!!
- New Independent Fellowship position in Microbiology to launch your lab in our department @johninnescentre.bsky.social (UK). We are conducting a broad search in the area of plant-associated microbial interactions. Message me if you have any questions. Apply here: www.jic.ac.uk/vacancies/in...
- Reposted by Bethan Lloyd-LewisFinally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁 Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
- Get in touch if you are interested in applying for an MSCA fellowship to come work with us on the mechanisms regulating epithelial cell fate decisions during mammary gland morphogenesis and cancer. Great environment in a vibrant city!
- Reposted by Bethan Lloyd-LewisCould this be the future of cancer prevention? Walid Khaled, a new ERC Advanced Grant recipient @cam.ac.uk, will work on a preventive vaccine for breast cancer. Learn more 👉 buff.ly/s6cBCwL #ERCAdG #CancerResearch #FrontierResearch @wtklab.bsky.social
- Reposted by Bethan Lloyd-LewisOur latest paper from is out! Congratulations to all members the lab that contributed over the years! No UMAPs in this one! @phar.cam.ac.uk @scicambridge.bsky.social Thanks to our funders @cancerresearchuk.org @breastcancernow.bsky.social
- CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer @wtklab.bsky.social and collaborators www.embopress.org/doi/full/10....
- Reposted by Bethan Lloyd-Lewis🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)
- Reposted by Bethan Lloyd-Lewis"Welsh is not a “minority language.” It is an indigenous language of Britain. It’s a language that grew here, shaped by the deep time of these islands – by the millennia it has spent in, and of, this land, shaping it and being shaped by it." nation.cymru/opinion/wels...
- Reposted by Bethan Lloyd-LewisPls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!
- Reposted by Bethan Lloyd-LewisCheck out our latest Comment in Nature Cell Biology on #autophagy (the mechanism that cells of your body use to recycle damaged material and slow ageing). While declining autophagy is often seen as a hallmark of #ageing, we explore emerging exceptions to this idea. www.nature.com/articles/s41...
- Reposted by Bethan Lloyd-LewisA great tribute to David Stevens, a terrific cell biologist and missed by so many of his friends and colleagues. As they say 'one of the good guys'. journals.biologists.com/jcs/article/...
- Reposted by Bethan Lloyd-LewisAre you enjoying all the exciting science at #biologists100? Want to spread the love of developmental biology to your friends and family? Together with @bsdb.bsky.social, we've produced a documentary video to showcase the fascinating world of #DevBio: 🎥
- Reposted by Bethan Lloyd-LewisIf you’re a PhD or postdoc developmental biologist in the UK who cares about the field and the community, please nominate yourself to join the BSDB committee. Great opportunity to get involved, have real input and give back to the community @bsdb.bsky.social #biologists100
- Reposted by Bethan Lloyd-LewisWe are looking for a doctoral candidate to join the lab! If you are interested in working with human breast tissue samples straight from the clinic and do not fear large data sets, this might just be your dream project ☺️ Apply now ⬇️ ats.talentadore.com/apply/vaitos... 📸 @oonapaavolainen.bsky.social
- Reposted by Bethan Lloyd-Lewis
- The de-extinction company Colossal Biosciences wants to bring back the mammoth, and it’s starting with a woolly mouse. Read more here: buff.ly/xKPLn1c
- Reposted by Bethan Lloyd-LewisJOB ALERT We are seeking a Computational Research Assistant or Research Associate to help drive an ambitious multiomics ageing project part of the NMGN Mouse Ageing Cluster. www.jobs.cam.ac.uk/job/49939/ @scicambridge.bsky.social @phar.cam.ac.uk @cambridgebiosci.bsky.social
- Reposted by Bethan Lloyd-LewisWhat do we mean by ‘mechanism’ anyway? @dev-journal.bsky.social Executive Editor @katherine-brown.bsky.social gives her perspective on the recent article "A case for broadening our view of mechanism in developmental biology" by @biyolokum.bsky.social @swathiarur.bsky.social and Mansi Srivastava:
- Reposted by Bethan Lloyd-LewisMy 3 favourite things about being a scientist: my full time job is to solve mysteries (how cool is that!), constantly being amazed by how beautiful & surprising the natural world is, getting to work w/ people who are smarter than me & have skills I can only dream of having on problems I care about.
- Reposted by Bethan Lloyd-LewisWe've been awarded a UKRI MRC grant to examine the causes and consequences of #heterochromatin hypomethylation in cancer 🥳. #postdoc opportunity coming in the near future. #epigenetics. Please share with anyone who might be interested.
- Reposted by Bethan Lloyd-LewisLooking for something fun to read? Here’s a #popsci piece I did on the crazy history of cilia and left/right patterning in embryos. Remember #devbiolwriteclub Bluesky Boot Camp starts Monday Dec. 2! Please RS (re-skeet?) nautil.us/the-anatomic...
- Reposted by Bethan Lloyd-LewisPlease share this PhD opportunity in my new lab in Bristol, using protein design/ engineering to understand and build molecular motors to control intracellular transport. Working with @markdodding.bsky.social and Prof Dek Woolfson. www.findaphd.com/phds/project... www.swbio.ac.uk/biomolecular...
- Reposted by Bethan Lloyd-LewisWe are forming a patient advisory group to help shape our research on BRCA breast cancer prevention! Follow the link/scan the barcode for more info and to express interest. Please share! @wtklab.bsky.social www.stemcells.cam.ac.uk/about-us/eng...
- Reposted by Bethan Lloyd-LewisWe are happy to report that our journals and community sites now have Bluesky accounts. Follow them at: @dev-journal.bsky.social @jcellsci.bsky.social @jexpbiol.bsky.social @dmmjournal.bsky.social @biologyopen.bsky.social @the-node.bsky.social @prelights.bsky.social @focalplane.bsky.social
- Reposted by Bethan Lloyd-LewisEven though there are great #devbio and #biophysics starter packs, I felt #morphogenesis & #organogenesis was missing as a subfield :D Far from complete or full. Tell me if you want to be added! go.bsky.app/PB6s8PQat://did:plc:4bzbwekunhj4onto6kjjen7p/app.bsky.graph.starterpack/3lbd5a2wjac22
- Reposted by Bethan Lloyd-LewisDo you work in #DevBio and want to introduce the fascinating world of developmental biology to your family and friends? You can show them this science documentary, produced by the British Society for Developmental Biology, The Company of Biologists and Cambridge Filmworks! 📽️ youtu.be/avrmIs3vPUQ?...
- Reposted by Bethan Lloyd-LewisUpcoming Development Special Issue 'Lifelong Development' Beyond the embryo: tissue maintenance, regeneration & plasticity Guest eds: Meri Huch & Mansi Srivastava Deadline: 15 May 2025 All article types welcome #DevBio #Regeneration #StemCells journals.biologists.com/dev/pages/li...
