Matyas Bubna-Litic
Interested in mechanobiology, morphogenesis, organisers and synthetic embryo models.
Research Fellow in Mongera lab UCL | PhD in Mayor and Charras labs | YEN Committee
- Reposted by Matyas Bubna-LiticJob alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M
- Reposted by Matyas Bubna-LiticExcited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
- Reposted by Matyas Bubna-LiticMy group will investigate the stochastic morphodynamics of living systems at the interface of biophysical modelling and computational biology. I will announce positions for PhD students and postdocs in the coming months! Feel free to DM me if you are interested!
- Reposted by Matyas Bubna-LiticWe're in love with this cover image! 🧡 Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024: www.sciencedirect.com/journal/cell...
- Reposted by Matyas Bubna-Litic#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you. www.biorxiv.org/content/10.6...
- Reposted by Matyas Bubna-LiticPleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking. It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems. Preprint: www.biorxiv.org/content/10.6... [1/6]
- Reposted by Matyas Bubna-Litic🌈 Rainbow neurons on the move!🧠 MultiColor FlpOut of L3 optic lobe neurons projecting into the medulla neuropil. 📸 Image by Isabel Holguera. #FluorescenceFriday #DevBio
- Reposted by Matyas Bubna-LiticSearching for physical principles of morphogenesis In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory doi.org/10.1242/dev....
- Happy (and spooky) #FluorescenceFriday Switching from frogs (which are underrated btw) to zebrafish has really made me appreciate transparent tissues! 🐟 28 hpf, ⚪ nuclei, 🔴 F-actin
- Reposted by Matyas Bubna-Litic📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome! Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
- Reposted by Matyas Bubna-Litic1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details
- Pretty cool
- 🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
- Animal caps are back in fashion!
- Reposted by Matyas Bubna-LiticOur new paper is out in Dev Biol! 🎉 🐸🧬 We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning 👉 Read more here: doi.org/10.1016/j.yd... @devbiol.bsky.social @biouea.bsky.social
- Reposted by Matyas Bubna-LiticMouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
- Thank you for sharing! I'd like to highlight the concept of embryonic 'actuation' where a mechanical state change is caused by cells acting on each other through mechanics and/or biochemical signals but importantly not mediated by fate transitions.
- Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview buff.ly/Ea2ZoFg
- Reposted by Matyas Bubna-LiticGot stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...
- Reposted by Matyas Bubna-LiticI'm going to be advertising for a few positions in my group in the next couple of months for a big project on synthetic microbial communities. I would love to hear from you if you are interested and I'd also appreciate if everyone could share this far and wide!
- Reposted by Matyas Bubna-Litic✨Not a rainbow trout… a rainbow zebrafish 🌈 🐟 The expression of 10 different genes simultaneously including Hox genes along the body axis, somites, brain regions, skeletal muscle, and heart 🔬Image by Alice Sherrard, Gabby Jerz & Nipam Patel 🧪 #FluorescenceFriday
- Reposted by Matyas Bubna-Litic🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio
- Reposted by Matyas Bubna-LiticDev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social thenode.biologists.com/jobs/postdoc...
- Reposted by Matyas Bubna-LiticGot stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...
- ✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪 #FluorescenceFriday #DevBio
- Reposted by Matyas Bubna-LiticInteresting review about the role of ECM in development!
- Maybe it's time we rethink the idea that development is a cell centric process? In this beautiful review, María-del-Carmen and @stramerlab.bsky.social discussed how the ECM underlies and influences many morphogenesis processes from wing unfolding to mammary gland development. doi.org/10.1016/j.cd...
- Reposted by Matyas Bubna-LiticWe are searching for an enthusiastic scientist to join our team and establish annual killifish as a model system for early developmental biology and biophysics! @embl.org @embldbunit.bsky.social Apply here: embl.wd103.myworkdayjobs.com/EMBL/job/Hei... Please re-post 🙏
- Reposted by Matyas Bubna-LiticThrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch
- Reposted by Matyas Bubna-LiticVery happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
- Reposted by Matyas Bubna-LiticI was looking through my old microscopy videos, and found this perfect shot of a macropinosome forming through the collapse of an actin-driven membrane ruffle (cyan). Immediately, CRYI-A (orange) is recruited to the vesicle to finish the job. Still in awe with this process after all those years!
- Reposted by Matyas Bubna-LiticA cryosection immunofluorescence image of a Xenopus embryo showing fibronectin in 🔵, DAPI in ⚪, and Sox9 - a marker of the neural crest in 🟠. Image credit: Kai Weissenbruch from UCL #FluorescenceFriday #devbio
- Reposted by Matyas Bubna-Litic🪼 How did the animal body plan evolve? This ‘fundamental’ study in Clytia sheds light on how Wnt3 coordinates both gene expression and planar cell polarity during axis formation, offering key insights into the origins of morphogenesis. buff.ly/e1Un958 #DevBio
- Reposted by Matyas Bubna-Litic🔊 We are recruiting a postdoc to join us @crick.ac.uk and @ucl.ac.uk @ucl-ipls.bsky.social. Repost and help us spread the word and reach out if interested and have questions. Details and how to apply: www.ucl.ac.uk/work-at-ucl/...
- BSDB Bridging mechanics and genetics in early development at University of Warwick was great fun and I am grateful for the opportunity to present my PhD work.
- Full PDF of the paper about how mechanical cues interplay with morphogen signalling is available here: www.researchgate.net/publication/...
- Reposted by Matyas Bubna-Litic#Argonautes2025 - argonautes.img.cas.cz Join us in Prague 27-30/8/2025 for the next edition of the Argonaute meeting #miRNA #siRNA #piRNA & #PIWI Abstract submission for talk selection deadline is 30/6! Please, spread the word @rnasociety.bsky.social @rti-umasschan.bsky.social
- Reposted by Matyas Bubna-LiticNext Thurs, join us for the next Western VGZT 🌙 🗓️ Thursday, June 19 ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Featuring: @jesseveenvliet.bsky.social 👉Exploring physiological constraints by sculpting with stem cells @sermenchero.bsky.social 👉What marsupials can teach us about time
- Reposted by Matyas Bubna-Litic📣 New paper out! How do thousands of cells shape the emergent geometry of the avian embryo? We identify distinct, independently controllable mechanisms that contribute to embryo size and shape. @alex-plum.bsky.social @bensteventon.bsky.social @Guillermo Serrano Najera www.nature.com/articles/s41...
- Reposted by Matyas Bubna-Litic1) Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood. #zebrafish #gills #microscopy
- Reposted by Matyas Bubna-LiticHooray. Yesterday, my very first #Hydra paper was accepted! An exciting time for a career #Drosophilist. Big congratulations to @anaisbailles.bsky.social, who set up the Hydra system from scratch. Thanks Carl Modes for the liquid crystal theory. @mpi-cbg.de Preprint: www.biorxiv.org/content/10.1...
- We had a lot of great entries in the YEN Image Competition. Some of these made it to the top 10 after a vote by developmental biologists attending the YEN 2025 Conference. Check them out here:
- See the winners of the YEN Image Competition 2025. Thanks for everyone who sent us their amazing embryology images! #yen2025 thenode.biologists.com/yen-image-co...
- Reposted by Matyas Bubna-LiticSee the winners of the YEN Image Competition 2025. Thanks for everyone who sent us their amazing embryology images! #yen2025 thenode.biologists.com/yen-image-co...
- Reposted by Matyas Bubna-LiticWelcome to YEN 2025. We are kicking off today with Peter Rugg-Gunn who presented their impressive in vitro system of implantation and post-implantation developmentm
- Reposted by Matyas Bubna-LiticWe heard from Yuri Takashi from @geneticscam.bsky.social showing ex vivo induction of EMT and BMP signalling in chick embryo explants.
- Reposted by Matyas Bubna-Litic@martanska.bsky.social from @pdncambridge.bsky.social presenting her work with gastruloids on how mechanical properties of individual cells can affect tissue level properties and morphology.
- Reposted by Matyas Bubna-LiticLaure de Chancel from @institutcurie.bsky.social all the way from Paris talking about chromatin mechanics and how it changes during zygotic genome activation.
- Reposted by Matyas Bubna-LiticStarting the short talk session we have Jake Cornwall Scoones from the @CrickLab on using NeMECiS to explore and engineer synthetic CREs to modulate gene regulatory behaviour. Check out their pre-print and workshop!
- Reposted by Matyas Bubna-LiticThank you to everyone who has registered to attend YEN 2025! You can still register for online attendence to hear talks and look at online posters. We have sent out a programme to our attendees so if you haven't heard from us just email us or reach out on social media. #yen2025
- Reposted by Matyas Bubna-LiticCheck out the YEN 2025 Image Competition! We have many beautiful entries of all sorts of model organisms. Thanks again to all who contributed. #YEN2025 #YENImageCompetition Scan the QR code to vote and see full sized images.
- If you care about mechanics in biological systems give IPLS a follow!
- 📢Registration is open for our IPLS Annual Symposium, 11th June 2025! We will showcase exciting #interdisciplinary #research performed by IPLS researchers and collaborators. Limited spaces, register early to avoid disappointment 👇 ucl.ac.uk/physics-livi...
- Reposted by Matyas Bubna-LiticWe are happy to announce student and postdoc speakers. Thanks to all who submitted an abstract! #yen2025
- Register now to attend YEN 2025. Looks like an amazing line up of speakers! #yen2025
- Reposted by Matyas Bubna-LiticYou can still register to attend the YEN 2025 Conference for FREE! You can join online or in person at the Crick Institute in London on Monday 19th May. Check the comments for student/postdoc talks!
- Reposted by Matyas Bubna-LiticOur special issue contains some very interesting articles on organiser biology, ranging from cnidarians to amphibian to mammals. Check them out.
- Reposted by Matyas Bubna-LiticCheck out the YEN 2025 Image Competition! We have many beautiful entries of all sorts of model organisms. Thanks again to all who contributed. #YEN2025 #YENImageCompetition Scan the QR code to vote and see full sized images.
- Reposted by Matyas Bubna-LiticCheck out the YEN 2025 Image Competition! We have many beautiful entries of all sorts of model organisms. Thanks again to all who contributed. #YEN2025 #YENImageCompetition
- Reposted by Matyas Bubna-LiticAnd this is the final batch. Vote by scanning the QR code.
- Reposted by Matyas Bubna-LiticThis #FluorescenceFriday feels like fluorescence xmas! Thanks for all your submissions to the YEN Image Competition. Excited to see so many spectacular visualisations of embryonic development and stem cell biology! #YEN2025
- Reposted by Matyas Bubna-LiticREMINDER: Last chance to submit a scientific picture or art of a embryos, stem cells or organoids to the YEN Image Competition. Deadline is 1st May! #YEN2025
- Reposted by Matyas Bubna-LiticReminder that the YEN Image Competition closes next week on the 1st May! It's a great opportunity for students and postdocs to promote their research. Send us your images by email (details below)
- Happy #MicroscopyMonday! I was optimising some stainings a couple years ago (this one is Stage 32 with sodium borohydride to reduce autofluorescence). Any #Xenopus people know what the rosette-looking clusters around the eye are doing? By the way, check out YEN Image Competition #YEN2025 ;)
- Great opportunity to highlight your research and celebrate the great imaging possibilities in dev bio! #YEN2025
- Reposted by Matyas Bubna-LiticWhat to look forward to at #YEN2025? Well we asked you about your field and these were the 100 most common words.
- Reposted by Matyas Bubna-LiticIf you are a PhD student or postdoc working on stem cell, organoid or developmental biology you can sign up to present at #YEN2025 Go to forms.gle/fxtmNHjEziVT...
