Lydia Finley
cell biologist with an interest in pretty much everything
ski.edu/finley
- Reposted by Lydia FinleyLab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!
- I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵
- Reposted by Lydia FinleyJust out in @science.org: Together with the lab of @wilhelmpalm.bsky.social, we used sequential in-vitro/in-vivo CRISPR screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
- Reposted by Lydia FinleyJust out in @science.org: Together with the lab of @johanneszuber.bsky.social, we used sequential in-vitro/in-vivo screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...
- Reposted by Lydia FinleyCheck out the symposium organized by our CoE, excited to have Marcia Haigis, @lydiafinley.bsky.social, Matthias Hebrok and Tom MacVicar over in Helsinki in November. Sign up by October 22nd 👇
- Excited to announce our Stem Cell Metabolism Symposium organized in Helsinki on November 12th. Fantastic invited speakers Marcia Haigis, Lydia Finley, Matthias Hebrok and Tom MacVicar. Sign up by Oct 22nd, free of charge, welcome! @hilife-helsinki.bsky.social @helsinki.fi @stemmprogram.bsky.social
- Reposted by Lydia FinleyHappy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social Here is a short paper thread. #tuberculosis #macrophages 🦠 www.biorxiv.org/content/10.1...
- Reposted by Lydia FinleySuper excited to share new review on metabolic stress and adaptations in pancreatic cancer to these stresses from @cssheehan.bsky.social jci.org/articles/vie... 1/6
- Reposted by Lydia FinleyProudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
- Reposted by Lydia FinleyOur paper on regulation of BCAA catabolism by mitochondrial calcium signaling is out! Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma | Science Advances www.science.org/doi/10.1126/...
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- Reposted by Lydia FinleyI'm excited to share our latest story from the @lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/
- Reposted by Lydia FinleyHappy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells www.nature.com/articles/s41... @metastem.bsky.social @helsinki.fi @ki.se @helsinki-biotech.bsky.social out now in @natcomms.nature.com A thread 🧵 1/9
- Reposted by Lydia FinleyShowcase your research! Submit your poster abstract by April 16 (11:59pm MST) to join speakers @lydiafinley.bsky.social, Ralph J. DeBeradinis, & Keynote Navdeep Chandel. Apply now: keysym.us/KSMetabDev25. Can't attend? Access insights On Demand for 6 months post-conference! #KSMetabDev25 #cellfate
- 2 weeks to go to the annual NYAS cancer metabolism symposium, April 8 at NYU Langone! www.nyas.org/shaping-scie... Register now using code CancerMetabolism10 for a 10% discount. And hurry! Last year we sold out! cc: @lyssiotislab.bsky.social @marcusgon.bsky.social
- Reposted by Lydia Finleywww.quantamagazine.org/how-metaboli... Seems like a good time to remind you of an upcoming meeting on this exact topic: www.keystonesymposia.org/conferences/...
- Reposted by Lydia FinleyWe are 2 weeks out from the @NYASciences Cancer Metabolism meeting - still time to register! Join us for: Exciting science ✅ Awesome speakers ✅ Great camaraderie ✅ Science jokes⚠️ Celebrity appearances‼️ (probably not) Please circulate 🔁 events.nyas.org/event/16a78a...
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- Reposted by Lydia Finley1/Happy to share a new paper reporting a metabolic approach to radiosensitization in lung cancer, from Rachel Chiang, Faith Zhang and colleagues at UT Southwestern Radiation Oncology and @cri-utsw.bsky.social www.science.org/doi/10.1126/...
- Reposted by Lydia FinleyNew preprint time!! This one has been brewing in the lab for ~8 years describes a strategy for tumor selective WNT suppression. It was led by an amazing (then) grad student, Jill Zimmerman, with help from a host of lab members and collaborators along the way. www.biorxiv.org/content/10.1...
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- Reposted by Lydia Finley📢3 weeks left to submit your abstract for the Cancer Metabolism Showcase and Workshop!📢 We already have over 150 registrants! Sign up for free today at www.cancermetabolismshowcase.org
- Reposted by Lydia FinleyExcited to share a recent preprint by Oliver Newsom, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation.
- Defined media reveals the essential role of lipid scavenging to support cancer cell proliferation biorxiv.org/content/10.1101/202…
- Reposted by Lydia FinleyHappy to share our new #NIHfunded study! Led by Kath Oñate + crew of #WomenInSTEM 💪🏽💪🏻💪, we ID potential of normal mesenchyme to restrain #inflammation, epithelial identity, & #pancreaticcancer via KITL, a cue lost in transition to a CAF state. Now at Cancer Discovery aacrjournals.org/cancerdiscov...
- Reposted by Lydia FinleyWe are soliciting poster and short talk abstracts for the NYASciences Cancer Metabolism meeting. Just around the corner - join us for awesome metabolism in the Big Apple 🍎 Speakers: Kivanc Birsoy, Christine Chio, Marcia Haigis, Andy Intlekofer, Thales PapaG, Jared Rutter, Dan Wahl, Eileen White
- Massive work from Jess Spinelli's lab at UMASS demonstrating a SECOND electron carrier in the mammalian ETC: www.cell.com/cell/fulltex...
- Why does this matter? Ubiquinone (the OG) loves to deposit electrons on oxygen; rhodoquinone (newbie) is happy to give them to fumarate. Opens up many possibilities for unappreciated redox circuits in our cells. Also, just a great read. Congrats to the Spinelli lab (not on BlueSky?)
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- Our latest preprint identifies (targetable!) metabolic programs intrinsic to different cancer cell states in rhabdomyosarcoma, out just in time for @katrinaparas.bsky.social's thesis defense tomorrow!
- Reposted by Lydia FinleyI hope you will join @lydiafinley.bsky.social and me for two days of great science on metabolic support of development and cell fate. Deadline for scholarships and short talk abstracts is Feb. 6.
- There is an amazing lineup of metabolism talks at this meeting. Chicago is going to be THE place to be for all things cell metabolism. Would tag people if I could figure out who's on here 🧐 🤗
- Excited to co-chair #ASBMB2025 with the incredible Dave Pagliarini! This year’s ASBMB meeting promises to showcase cutting-edge science, foster dynamic collaborations, & inspire new ideas. Don’t miss your chance to be part of it—register & submit your late breaking abstracts. t.co/UwgMdxBo15
- HUGE congratulations to @paigearnold.bsky.social for being named a @hhmi.bsky.social Hanna Gray Fellow! A well-deserved recognition for all of your accomplishments and promise: I can't wait to see what you do next!!
- ⏰ Deadline is approaching (Feb 6!) to apply for scholarships + short talks for the Keystone meeting on metabolism in development! keysym.us/KSMetabDev25 The meeting is May 7-9 in Beverly, MA and will be a unique forum for discussing the role of metabolites in development. Hope to see you there!
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- Reposted by Lydia Finley1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...
- Reposted by Lydia FinleyApplications for the 2025 Bioorganic GRC are now live! Here is the link where you can check out the current line-up: grc.org/bioorganic-c...
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- Clear and comprehensive new go-to review from #NoTwitterNav (we're gonna need a new hashtag) delineating how mitochondria have distinct and context-specific roles in proliferation and fate determination www.annualreviews.org/content/jour...
- Reposted by Lydia FinleyJoin us in May, 2025 for a conference on Metabolic and Nutritional Control of Development and Cell Fate - one of the most interesting and fast-moving areas in cellular metabolism, with great relevance to disease: www.keystonesymposia.org/conferences/.... -RJD
