did:plc:i3zxtylf22ucu2thqd4ekspp
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- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppOur newest paper is out in NCB. @jrwconway.bsky.social designed a new FRET reporter, Illusia, to show the importance of integrin β1 phosphorylation dynamics in 3D invasion! Video: TNBC cells expressing Illusia with a Src (Saracatinib) or SHP2 (SHP099) inhibitor. www.nature.com/articles/s41...
- 🚨 New review out! We explore how extracellular acidification shapes key processes like endocytosis, neurotransmission & immune responses — and highlight tools to study it. 📖 Read more [https://doi.org/10.1016/j.ceb.2025.102531] w/ amazing collaborators 🙌 #CellBiology #Endocytosis #GPCR
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- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppWe've been studying mechanisms of resilience that protect lysosomes from damage and wrote a review on the topic. We consider lysosomal stress and damage on a spectrum. Please help me share as this is my first post 😀 and I don't have many followers! 🙏 Open Access: www.embopress.org/doi/full/10....
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- Reposted by did:plc:i3zxtylf22ucu2thqd4ekspp... and soon the structural glycoswitch: www.biorxiv.org/content/10.1...
- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppGrowth factors trigger receptor desialylation at the plasma membrane, galectin binding and subsequent endocytosis. => A proton pump driven glycoswitch @naturecellbiology.bsky.social : rdcu.be/eaLM9 #glycotime, @institutcurie.bsky.social, @cnrs.fr, @inserm.fr, #NIH, #CellBiol, #Cancer
- Thrilled to share our latest publication! We describe a novel acid-dependent mechanism regulating clathrin-independent endocytosis. This study was a fantastic collaborative effort with the labs of Ludger Johannes, Roberto Weigert, and Satyajit Mayor. nature.com/articles/s4155….
- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppHappy to contribute to the analysis of β1integrin endocytosis using @the.3i.social LLSM, now in @naturecellbiology.bsky.social rdcu.be/eaLM9 L. Leconte @christianwunder.bsky.social @aforrester.bsky.social @ewanmacdonald.bsky.social @institutcurie.bsky.social #inria @france-bioimaging.bsky.social
- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppCheck it out, powerful new method for optical imaging of the live ECM, from @hhmijanelia.bsky.social Group Leader Kayvon Pedram #proudofalumni #glycotime www.nature.com/articles/s41...
- Reposted by did:plc:i3zxtylf22ucu2thqd4eksppÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬 The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy www.biorxiv.org/content/10.1...
