Ivana Gasic
SNSF Assistant Professor @UNIGE
www.gasic.net
- New preprint from the lab 🎉: γ-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target α- and β-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades γ-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.
- Sad to miss this year’s ASCB meeting! But the lab is represented - don’t t miss @ac-almeida.bsky.social and her poster P0101. She will take you into the world of tubulin quantity control, microtubule dynamics, cell and tissue architecture.
- Heading to #CellBio2025 @ascbiology.bsky.social @embo.org? Stop by my poster P0101 tomorrow (Sun, 12:45 PM) in the session “Cytoskeleton and Motility-Microtubule Organization and Dynamics”. Looking forward to lively discussions on tubulin regulation & microtubule organization. See you in Philly!
- Lab’s 2nd story aired today! Fantastic @ac-almeida.bsky.social cracks the cellular function of tubulin autoregulation - an over four decades old enigma! Read on to learn how she deployed human 3D cell culture models to link tubulin homeostasis to tissue organization & viability. Bravo Ana! 👏🏻🍾
- 🔎New preprint! We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture. Big thanks to @ivanagasic.bsky.social and team! Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5) www.biorxiv.org/content/10.1...
- Arresting mitosis with visible light! Brilliant Victoria von Glasenapp from the Gotta and Winssinger labs @UNIGE develops a cool photo-caged PLK1 inhibitor, which we deploy in 3D spheroids to control mitosis with exquisite spatio-temporal precision. Check out the original article: lnkd.in/eTnzy5Nc
- When you come out of your midterm evaluation and your amazing team surprises you with these beauties 😍💐! Thank you, the ProMiCe team, for these flowers, support, and the brilliant work you are doing 🥰🙏!
- Hello Bluesky community! What a better way to introduce myself and my research team than post our lab’s first paper freshly off press 🥳🍾 We reveal how tubulins regulate the stability of their mRNA via reversible sequestration of TTC5. Bravo A. Batiuk and all coauthors 👏🏻🥂 doi.org/10.1038/s414...