As generalized before, most cancer promoting genes are enriched in embryonic neural/neural stemness cells, incl. KRAS/HER2/EGFR/STAT3.
They confer cancer cell with neural stemness, which determines tumorigenicity&pluripotency in cells.
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A targeted combination therapy achieves effective pancreatic cancer regression and prevents tumor resistance | PNAS
Pancreatic ductal adenocarcinoma (PDAC) has one of the lowest cancer survival rates.
Recent studies using RAS inhibitors have opened the door to mo...