Michael Fischbach
Liu (Liao) Family Professor of Bioengineering, ChEM-H @Stanford.
- Reposted by Michael FischbachCool germinal center acrobatics from Juhee Pae et al, check it out! www.nature.com/articles/s41...
- Reposted by Michael FischbachThis pair of papers demonstrating strong and systemic immune responses to skin commensals applied topically to unbroken skin, including induction of B cells for vaccination. www.nature.com/articles/s41... www.nature.com/articles/s41...
- Reposted by Michael FischbachThese are my favorites too! 🤯
- Reposted by Michael FischbachWhat an amazing story that was such a blast to collaborate on with @mfgrp.bsky.social lab!!! Phenomenal work led by @djenetbousbaine.bsky.social and all co-authors!! Unroll this thread and be amazed 🤯👇🏾
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachScientists turned a harmless skin bacterium into a powerful vaccine delivery tool, boosting immunity in the lungs and nose. @mfgrp.bsky.social @djenetbousbaine.bsky.social @nature.com t.co/xXXCJx5VYm #ImmunoSky 🧪
- Reposted by Michael FischbachA typical project for an incoming graduate student might involve 1–2 weeks of planning and 2–5 years of execution, [yet] the problem you choose will influence the impact of your work just as much as the quality of your execution. @mfgrp.bsky.social open.spotify.com/episode/6KMh...
- Reposted by Michael FischbachInsanely creative and original immunology and bioengineering work from the Fischbach Lab at Stanford with high translational potential Full article in NATURE: www.nature.com/articles/s41... Follow the scientists: @mfgrp.bsky.social @djenetbousbaine.bsky.social @katebauman.bsky.social
- Reposted by Michael FischbachBeautiful work with exciting implications for topical vaccination by @mfgrp.bsky.social ✨ Give this a read 👇
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachVaccines, but make it skincare!🧴🧬 Congratulations to Stanford BioE Professor Michael Fischbach @mfgrp.bsky.social & @djenetbousbaine.bsky.social for engineering a skin bacterium that could lead to needle-free vaccines.
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachCheck out our last pub. from @mfgrp.bsky.social al lab! We discovered that skin commensal microbes induce systemic and local B cell responses upon colonization and took advantage of this knowledge to create topical vaccines using engineered skin microbes. Please read the thread for details.
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachYour hand lotion is now also a vaccine. Hot damn
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachTwo fascinating papers just out in Nature @natureportfolio.bsky.social: www.nature.com/articles/s41... www.nature.com/articles/s41...
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View full threadReposted by Michael FischbachIlluminating thread by author @mfgrp.bsky.social bsky.app/profile/mfgr...
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachBrilliant work congrats to the authors!
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachAwesome thread from @mfgrp.bsky.social about what might be the most amazing result you'll hear about in 2024: antigens stuck on the surface of the skin bacterium S. epidermidis generate a strong immune response in mouse.
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachA remarkable story from @mfgrp.bsky.social and colleagues: immunization via skin S. epidermidis generates systemic and mucosal antibody responses.
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachAnd in a Nature publication double-header, @mfgrp.bsky.social @stanford-chemh.bsky.social collaborates with Yasmine Belkaid and workers in this study reporting on local immune response including antibody generation in response to skin commensals: www.nature.com/articles/s41...
- Reposted by Michael FischbachThis is the most amazing thread since they did a similar thing to cure a cancer
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachWonder. Awe. Excitement. Very cool thread on a very cool finding. #IDSky
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachHoly shit this is amazing!!! 🤯
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael Fischbachdiscovery that a skin microbe can, without inflammation, induce a systemic B-cell response... and then engineering that microbe into a potent vaccine platform that can be applied as a topical cream. amazing work from @djenetbousbaine.bsky.social and @mfgrp.bsky.social! www.nature.com/articles/s41...
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachAn amazing discovery, and a very informative and engaging thread. Could develop into a transformative new mode for efficient vaccination
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael Fischbachone to savor over the holidays. also so cool to see how the directions of the work between @mfgrp.bsky.social and Belkaid labs diverged.
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachBrilliant 🧵on a fascinating study demonstrating potent systemic and mucosal antibody responses to the common skin commensal Staph. epidermidis. Engineered S. epi expressing or displaying unrelated antigens elicited protective immunity,suggesting it could serve as topical vaccines. 💉
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachCo-opting a skin commensal to design new vaccines! An amazingly creative and thoughtful new approach that integrates our knowledge of immune system responses. #ImmunoSky
- Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
- Reposted by Michael FischbachCheck out this bombshell publication by Michael Fischbach @mfgrp.bsky.social and coworkers @stanford-chemh.bsky.social @stanfordmedicine.bsky.social, imagine a cancer immune therapy/vaccine where treatment begins and ends with a painless topical skin treatment! 🤯 www.nature.com/articles/s41...
