Ayusman Sen
Active autonomous systems; synthetic nano and micromotors; micropumps; nanotechnology, systems chemistry. sites.psu.edu/sengroup/
“It's tough to make predictions, especially about the future.” Yogi Berra
- Reposted by Ayusman SenStreet art memorializing Alex Pretti in Seattle. Per r/Seattle, it was painted on a building facing Swedish Hospital in the First Hill neighborhood www.reddit.com/r/nursing/co...
- Reposted by Ayusman Sen🧪🧠 New preprint out! Soft Hardware, Flowing Software We introduce reconfigurable microfluidics as an active control layer for chemical computation. Geometry, and flow, and not molecular redesign, programs function. Great work by Piet! chemrxiv.org/doi/full/10....
- Reposted by Ayusman SenPowerful call to action from @cdelawalla.bsky.social founder of @standupforscience.bsky.social timmermanreport.com/2026/01/scie...
- Reposted by Ayusman SenRest in Peace Alex Jeffrey Pretti🙏🏾 The VA ICU Nurses send him off right 💔
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- Reposted by Ayusman SenHappy New Year #disappointingaffirmations
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- We are on the front cover of the last issue of 2026! Thanks to the artistry of @sanjanakmani.bsky.social and thank you @pubs.acs.org Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...
- @leecronin.bsky.social Are these droplets alive?
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- Very cool! Suggests the possibility of intra-organelle navigation using pH gradients.
- @acs.org has posted a Research Headline Video on our paper: www.youtube.com/shorts/LPFlI... Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...
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- @philipcball.bsky.social @andrewbissette.bsky.social Is replication a strict requirement? What about a system that responds to the environment in ways that furthers its persistence. Does it not have "agency"? Is it alive?
- Wikipedia is 25! If you use it all the time and want to protect a future where knowledge is human-made, join me and donate now: donate.wikipedia25.org #Wikipedia25
- Me too!
- Reposted by Ayusman Sen“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
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- Congratulations, @sanjanakmani.bsky.social! Nice work!
- Reposted by Ayusman SenThis is a job for referees, not AI. (And any referee worth their salt would see that this example is an interesting hypothesis worth testing, not wild speculation beyond the data.)
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- Spiral patterns form by simply dropping protein solutions on to denser sugar solutions, showing reaction-diffusion pattern formation can be replicated by replacing the reaction-induced inhomogeneous solute distribution by evaporation-induced inhomogeneity: rdcu.be/eMUyR
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- Reposted by Ayusman SenOur latest work in @jacs.acspublications.org! Artificial system that can sense, grow, and adapt—just like cells! Our #droplets form directional filopodia in response to chemical cues- a step toward life-like materials. #SoftMatter #MatterToLife 🔗https://pubs.acs.org/doi/10.1021/jacs.5c11719
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- Our latest: Like bacteria, oil-in-water emulsions sense specific amino acids, sending out finger-like projections towards or away from the source! Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation. Great work by @sanjanakmani.bsky.social pubs.acs.org/doi/full/10....
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- Wonderful story!
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- Very well said!! Chemistry research is fueling Pennsylvania’s economy — so why are we defunding it? penncapital-star.com/commentary/c...
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- Reposted by Ayusman SenBeing a professor is so weird. You are constantly having to act like you know things.
- Non-reciprocal predator-prey behavior among enzyme-attached particles. Nanobots play 'follow the leader' by chasing chemical trails in microfluidic device phys.org/news/2025-09... via @physorg_com
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- Not my experience too. I get many, many more likes and reposts from X. I suspect that Bluesky is mostly confined to the US and UK, while X has many more international scientific subscribers.
- Should be a must reading for students thinking about nanotechnology and no just the techno types.
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- Fellow motorists, follow the roadmap for an exciting journey! Many thanks to Samuel Sanchez and others for their insights:
- Actually, most editors do favor papers on trendy topics but one hopes for an occasional eccentric one. Do we have eccentric AIs?
- All AI is based on past patterns and, by definition, cannot predict a scientific “black swan.” Of course, human editors and reviewers can also fall short but, at least, there is hope!
- Absolutely!
- We are on our way to designing intelligent communicating systems involving particle populations that carry out different tasks. Non-reciprocal chemotactic movement in enzyme cascade under flow-free conditions: Cell Reports Physical Science www.cell.com/cell-reports...
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- Happy to be part of this exciting conference in a spectacular setting! PhysicsOfLifeLMU @PhysOfLifeLMU Conference on Intelligent Active Matter. We still have some open slots for attending this small scale workshop and presenting posters. Please send an email to frey@lmu.de iam.physik.lmu.de
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- This is so true and vital to our technological leadership in the world. I hope the politicians who care about this country pay attention. Science Magazine - US must support chemistry research www.sciencemagazinedigital.org/sciencemagaz...
- Our perspective on swarm intlligence in nanomotors is out in Nature Review Materials. Fun collaboration with friends across the Atlantic. doi.org/10.1038/s415...
- Indeed, it is. There is never a closure and certainly no redemptive arc when someone so dear to you passes away. Thanks for sharing.
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- Re: Hazen/Wong paper on mineral complexity. Different reaction conditions lead to different stable products. Carbon forms diamond, graphite, fullerenes. Which has greater functional information? Diamond and graphite can interconvert. Thus, one could go from higher to lower "functional information."
- Or harder to spot because of the greater noise level? The number of researchers, the number of papers, the number of journals have all been growing exponentially. Also, breakthroughs achieved in some fields take longer to discern, e.g. experimental biology vs theoretical physics.
- A positive step that I can't see happening in the U. S.
- 👇
- My wonderful colleague 👇
- Indeed! Love the city.
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- Happy to have played a part! Go motoring!!

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- Highlighting wonderful work by my colleague, Stewart Mallory www.earth.com/news/tiny-pa...