robertomunita
Assistant Professor @UChile | RNA lover | Splicing, RNA modifications, ncRNAs, RT-LAMP
- Reposted by robertomunitaIt has been widely reported that the inclusion of pseudouridine or other uridine analogs in exogenous RNA prevents innate immune responses. This is why mRNA vaccines have these modified nucleotides (Moderna = modified RNA). We find something else is going on.
- Reposted by robertomunitaSWARM is an AI framework for nanopore direct RNA sequencing that detects m6A, pseudouridine (Ψ), and m5C mods at single-nucleotide & single-molecule resolution. Key innovation: Crosstalk-aware training with non-target mods & validated cellular signals to reduce false positives. 2/6
- Reposted by robertomunitaKATMAP infers splicing factor activity and regulatory targets from knockdown data - @daspliceisright.bsky.social go.nature.com/47ycrMJ
- Reposted by robertomunitaDNA and RNA modification mapping methods based on next-generation sequencing and long-read sequencing technologies go.nature.com/47yAbPc
- Reposted by robertomunitaICYMI: New Online! Single-cell research in Latin America and the Caribbean builds genomics datasets for equitable AI-powered precision medicine
- Reposted by robertomunitaICYMI: New Online! The new era of single-molecule RNA modification detection through nanopore base-calling models
- Reposted by robertomunitaNew Online! Revealing the hidden coding potential of the human genome
