Byron Lab
🔬 Cell adhesion networks lab
🥼 A new cell systems biology team
📍 University of Manchester, UK
🔗 linktr.ee/TheByronLab
- Reposted by Byron LabWe are very happy to share our latest work exploring the role of newly synthetized integrin-α5 using RUSH. We found that a subset goes to the PM via unconventional secretion! Big thanks to all involved! Read more at doi.org/10.1083/jcb.... @mathildemathieu.bsky.social @martina-lerche.bsky.social
- Reposted by Byron LabDelighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...
- Reposted by Byron Lab🌍🌎🌏Open to students worldwide! I m super excited for this project 🎉
- 🧠 Fully funded 4-year PhD studentship 🧠 Please repost BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin. www.findaphd.com/phds/project...
- Reposted by Byron Lab🧠 Fully funded 4-year PhD studentship 🧠 Please repost BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin. www.findaphd.com/phds/project...
- Two days left to apply for a Medical Research Council-funded PhD opportunity in the lab. This is a student-led project, so you can work with us to develop an exciting project in a research area of mutual interest! www.bmh.manchester.ac.uk/study/resear... @mcf-uom.bsky.social @fbmh-uom.bsky.social
- Fantastic talks from the lab at this week's @mcf-uom.bsky.social Lab Showcase - well done Josie, Julio and Morgan! Calls for cake 🍰
- Reposted by Byron LabHappy to share that my PhD has finally taken the shape of a paper! ✨ Huge thanks to all authors, especially @davidbrueckner.bsky.social & @ehannezo.bsky.social for leading the modeling and @raimonsunyer.bsky.social & @xaviertrepat.bsky.social for their invaluable supervision. 🧵👇
How do cells navigate up gradients of adhesive proteins? 🤔 Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood We show that passive friction directs cells & explains complex trajectories on gradients 👉 www.nature.com/articles/s41...
- Shoutout to our fantastic project and masters students! 🧪✨ It was a pleasure to have you in the lab @mcf-uom.bsky.social – your energy and hard work truly made a difference! 💫 #LabLife #CellBiology #ResearchStudents #ThankYou #AcademicLife @fbmh-uom.bsky.social @manchester.ac.uk
- MSc student Sylvia and honours project student Jess Osborn recently completed their projects in the lab. And this time last year, we said farewell to MSc student Yue Li and honours project student (and then intern) Isobel Gall. Wishing you every success in your next steps 👏 @fbmh-uom.bsky.social
- Reposted by Byron LabMy lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
- Fantastic time at the Adhere2 conference on cell adhesion - on the lovely Dalmatian coast. #CellBiology #research #conference
- Excellent science, inspiring discussions … and scientists in the sea! Special thanks to Andreja, @bengoult.bsky.social, Vasso, Nina, Marina and Marija for organising such a great meeting! 🐬 🐬
- Very enjoyable visit to the @qmbci.bsky.social yesterday, discussing fantastic science and presenting our work 🔬 Thank you for warmly hosting, @tysonsharp.bsky.social! @susanagodinho.bsky.social @drtanyasoliman.bsky.social @cruk-cityoflondon.bsky.social @qmul.bsky.social #research #collaboration
- Reposted by Byron LabA new £50m Medical Research Council Centre is set to study how environmental exposures cause chronic inflammatory diseases. www.manchester.ac.uk/about/news/n...
- Reposted by Byron LabExcited to share our most recent study on #integrintraffic #cancer #migration #focaladhesion by @ivaskalab.bsky.social @drpaulinamoreno.bsky.social Niklas Jäntti et al www.sciencedirect.com/science/arti...
- Reposted by Byron LabWe're Hiring: Postdoctoral Position in Cross-Linking Mass Spectrometry Join our team at the Center for Structural Mass Spectrometry at the Martin Luther University Halle-Wittenberg (Sinz Lab) to develop and apply cross-linking mass spectrometry techniques for studying protein interactions.
- Reposted by Byron LabDelighted to advertise a collaborative postdoc position available in the lab to develop new proximity labelling tools, funded by a BBSRC Transformative Research Technology grant: www.jobs.manchester.ac.uk/Job/JobDetai... #ChemicalBiology #SyntheticChemistry
- Just back from a fantastic research visit to the Regina Elena National Cancer Institute, Rome, working with Dr Paola Nisticò and the Tumor Immunology & Immunotherapy team 🔬 Amazing cancer biology research, inspiring discussions and such warm hospitality from the team ☀️ #CancerResearch #Collaboration
- Big thanks also to the @manchester.ac.uk @fbmh-uom.bsky.social School of Biological Sciences Internationalisation Award for supporting the visit to build exciting collaborative research networks 🌍 Looking forward to what's next 💡
- Reposted by Byron LabHad a chat with @ajbrenes.com at #BSPR2025 about data reuse, and how some datasets, once combined and reused for a new biological question, are absolute gold. It's always worth depositing your data. 💿 Here are the statistics of his #HipSci dataset, which has remained at 2% after 6 years. 📈
- Reposted by Byron Lab🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!! www.nature.com/articles/s41...
- Reposted by Byron LabFree Hands-On Training in Mass Spectrometry Imaging (MSI)! A unique training opportunity in MSI, open to both national and international attendees in collaboration with BMSS and catapult. For more information please check this link: www.bmss.org.uk/meetings/bms...
- Reposted by Byron LabDo you want to play a pivotal role in groundbreaking research at IGC? In this role you will work at the intersection of computational and experimental science, leveraging cutting-edge technologies to address fundamental questions in genetics and disease. Apply by 31 March: edin.ac/3R5dEBU
- Reposted by Byron LabHappy to share our new publication in @naturematerials.bsky.social on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats @luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉 www.nature.com/articles/s41...
- Reposted by Byron LabHappy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
- Reposted by Byron LabIt’s #BritishScienceWeek and our researchers, academics and students have been at Manchester Museum! Students from far and wide, alongside the general public and visitors to the museum, have been finding out about the exciting work going on in the Faculty @officialuom.bsky.social.
- Reposted by Byron LabCome and find out how the Protein and Metabolite Analysis group can support your research at the Protein and Metabolite Analysis 2025 Showcase! 📅 31 March 2025 | 🕒 9am - 3:00pm 📍 Michael Smith Building Lecture Theatre Register here: www.eventbrite.co.uk/e/protein-me...
- Reposted by Byron Lab@the-node.bsky.social #biologists100 reporter @jens-cells.bsky.social is putting together a conference survival guide. What are your top tips for getting the most out of your conference experience.
- 🧪Getting ready for #biologists100; what’s the best way to prepare? 🤔 Conference Survival Guide Needed! 📝 If you could give ONE piece of advice to a first-time attendee, what would it be? Let’s help the newcomers thrive! ✨ #SciComm #ConferenceTips #AcademicLife #AcademicSky @the-node.bsky.social
- Reposted by Byron LabUnique opportunity to join the CytoMorpho Lab (in Paris ❤️) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required. Please Repost 🙏 thanks !
- Reposted by Byron Lab"Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties" and are distinct from other large EVs both in their content and morphology. This video shows a blebbisome (magenta) in the same field of view as forming migrasomes (yellow). www.nature.com/articles/s41...
- Reposted by Byron LabMaybe of interest to the talented ECR network of @themeshwork.bsky.social ? www.manchester.ac.uk/research/bic...
- Reposted by Byron LabHappy to share our new paper about working part-time in academia. We hope it can help to get the conversation going about this important aspect of EDI and research culture elifesciences.org/articles/106... @elife.bsky.social @emiliapsantos.bsky.social @englishse.bsky.social @hammofish.bsky.social
- Fantastic postdoc opportunities available @fbmh-uom.bsky.social! 💡 Please get in touch if you're interested in using biomaterials, cell biology, 'omics technologies and data science to investigate cell adhesion networks and gene expression in cancer #science #research #jobs #careers
- Early-career fellowships at the University of Manchester! To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers: www.bmh.manchester.ac.uk/research/sup...
- Reposted by Byron LabExcited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
- Reposted by Byron Lab#1 Happy to share our last work published in @NatureCellBio about a new cell cycle checkpoint that senses nuclear shape & mechanics to guarantee genome integrity www.nature.com/articles/s41.... Great work from @sol-herve.bsky.social & Andrea Scelfo in close collaboration with @katemiro.bsky.social
- Reposted by Byron LabDid you catch us on BBC Breakfast this morning? Dr Neil Dixon and Dr Micaela Chacón explain how biotechnology could be used to help us with our Christmas waste. Start from 17:45: www.bbc.co.uk/iplayer/epis...
- Reposted by Byron LabWorld leading researchers at our University are making an impact right around the world 🧬🔬 Here’s a taste of some of @fbmh-uom.bsky.social's most popular and interesting stories from 2024 👇 www.manchester.ac.uk/about/news/2...
- 📣 PhD opportunity in the lab! 💡 Are you interested in developing biomaterials to understand how cancer cells sense their surroundings to control gene activity? 🔗 For info on the project, and for details on how to apply, click here: www.findaphd.com/phds/project... 📧 Do get in touch if interested!
- 🧪 The PhD project will use material engineering approaches to model how force is transmitted from the extracellular microenvironment into the nucleus of cells to regulate gene expression. 📅 The closing date for applications is Friday, 31st January 2025, 5pm.
- ✨ This exciting, multidisciplinary project is funded by a major new Doctoral Landscape Award from the BBSRC @ukri.org to train a diverse community of motivated, inquisitive bioscientists within an innovative PhD-to-workforce framework. ℹ️ More about this here: www.manchester.ac.uk/about/news/u...
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View full thread💬 Please get in touch (linktr.ee/thebyronlab) if you are interested in joining us in @mcf-uom.bsky.social and @fbmh-uom.bsky.social at @official-uom.bsky.social! #postgrad #research #careers
- Reposted by Byron LabWe welcomed scientists from around the world to Bath this week for the annual Skin@Bath Symposium, who brought together global experts to discuss cutting-edge research in skin research, including therapies for skin-related disorders, such as skin cancers and arthritic psoriasis. #WeAreInternational
- Great to be at the Skin@Bath Symposium learning about all things skin! Thrilled to have presented our work in the squamous cancers session, expertly chaired by @walkolab.bsky.social from @qmulfmd.bsky.social First time at this meeting, so v nice to meet new colleagues @birdbathcharity.bsky.social
- Many thanks to Charareh Pourzand, @birdbathcharity.bsky.social, @uniofbath.bsky.social, for the organisation – and for preparing so far in advance the Skin@Bath conference dinner entertainment! 💃 #SkinResearch #Conference
- Reposted by Byron LabIt is becoming increasingly confusing to work out where to publish if you want to comply with your funders OA policy (or with your own principles). This tool is very helpful journalcheckertool.org
- Fantastic to see the insides (and outside) of the brand new Dalton building @manmetuni.bsky.social - amazing space housing the Faculty of Science and Engineering. @iamabyron.bsky.social gave a Department of Life Sciences Research Seminar with a great view of the city!
- Reposted by Byron LabGet down to the engineering building to see some NanoSIMS #UoM-TBM
