Tania Wong
Assistant Professor & Chancellor Scholar
Department of Microbiology, Biochemistry and Molecular Genetics | Center for Immunity and Inflammation | Rutgers New Jersey Medical School
Host-pathogen interactions, innate immune and metabolic responses
- Reposted by Tania WongToday’s #JEMjc @jem.org highlights the work of Alan Saltiel & colleagues @nature.com reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress. www.nature.com/articles/s41...
- Reposted by Tania WongAbsolutely stoked to have this published in @plosbiology.org We looked at the metabolism of #Klebsiella pneumoniae 🦠🧫. We not only demonstrated lineage-specific #metabolism, but that lineages can cross-feed and support each other. journals.plos.org/plosbiology/... #MicroSky #microbiology 🧬 🧪 💊
- 🚀 We’re hiring a Postdoc! Seeking expertise in spatial metabolite imaging and/or mass spectrometry to study how host metabolism shapes immune responses. If you're creative, collegial, and excited to push boundaries, we’d love to hear from you. Please share! 🔗 www.nature.com/naturecareer...
- 🚨 New review out from our lab! We’re pleased to share our latest article @cp-cellreports.bsky.social exploring the airway immunometabolic response to common bacterial and viral pathogens. Shout out to @ridhimaw.bsky.social, Eric Tang and Roy Wong. 👉 Read it here: www.cell.com/cell-reports...
- Reposted by Tania Wong#WeekendRead! #ImmunometabolismPower! Kunkemoeller @hannahprendeville.bsky.social @lydialynch.bsky.social &co show @natmetabolism.nature.com that not all fats are equal & that animal, & not plant, fats drive immune suppressive metabolites dampening NK & T cell anti #tumor responses!
- Truly honored and thankful to receive an R35 MIRA grant from NIGMS - grateful for the support and the opportunity to pursue our research on diet-mediated immunometabolic responses in the context of infectious diseases.
- Pleased to share our latest study @natcomms.nature.com! We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work! www.nature.com/articles/s41...
- Appreciate the Rutgers News feature on this year’s i3D Symposium. It was a great opportunity to bring together researchers across multiple disciplines. Thanks to everyone who contributed to a successful event. www.rutgers.edu/news/expandi...
- Reposted by Tania Wong🄰🅆🄴🅂🄾🄼🄴 Stubbusch et al 𝘚𝘊𝘐𝘌𝘕𝘊𝘌 Bacteria 🦠 repurpose Type VI Secretion Systems based on environmental cues: Nutrient-rich environments ➜ kill competitors Under starvation ➜ lyse neighbors to scavenge their nutrients Even “non-pathogens” shift from competition to predation as a survival strategy
- Pleased to have co-chaired the 2025 Rutgers Symposium with @jackhsu.bsky.social #hostpathogeninteractions #immunometabolism Many thanks to all our speakers! @aiinglim.bsky.social @shanluliu.bsky.social @roi1avraham.bsky.social @briandaniels.bsky.social and many others
- Congratulations @daneparkerlab.com! Rutgers NJ Medical School Faculty of the Year Award! Well deserved!
- Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇 www.biorxiv.org/content/10.1...
- Reposted by Tania WongItaconate modulates immune responses via inhibition of peroxiredoxin 5 @natmetabolism.nature.com www.nature.com/articles/s42... www.nature.com/articles/s42...
- Reposted by Tania WongSystemic inflammation impairs myelopoiesis and interferon type I responses in humans www.nature.com/articles/s41... @natimmunol.bsky.social
- Reposted by Tania WongBacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes @cp-cellreports.bsky.social www.cell.com/cell-reports...
- Thrilled to present my lab’s work at @escmid.bsky.social. Also chuffed to have bumped into fellow @klebclub.bsky.social member, Renee @fleemanlab.bsky.social!
- 🎉 It's official! Our lab website is LIVE! Come check it out to learn about our research, meet the team, and see what exciting things we're working on! www.taniawonglabrutgers.com
- Reposted by Tania Wong#LocationLocationLocation! @soleimanpourlab.bsky.social &co show @science.org that loss of mitochondrial functionality drives defective OXPHOS activating a retrograde signal from mitochondria to nuclei causing chromatin remodeling & immaturity in metabolic tissues www.science.org/doi/10.1126/...
- Reposted by Tania Wong#WeekendRead! #LipidPower! @miriammerad.bsky.social &co show @natimmunol.bsky.social that to get activated, #DCs steal from cell debris & produce their own cholesterol which is organized in plasma membrane lipid nanodomains! AXL reduces this process & its deletion augment anti-tumor immunity!
- Reposted by Tania WongSARS-CoV-2 breakthrough infections in previously vaccinated individuals are characterized by reduced activation of innate immune responses www.science.org/doi/10.1126/... @blishlab.bsky.social
- Reposted by Tania WongCome and join our team at St. Jude Children's Research Hospital! We are seeking a Sr Scientist to advance our research on immune responses to infection/vaccination. This is a financially stable position offering a highly competitive salary and excellent benefits. talent.stjude.org/careers/jobs...
- Reposted by Tania WongThanks to @cp-trendsendomet.bsky.social for giving us the opportunity to write about our favourite metabolite, fumarate. www.sciencedirect.com/science/arti...
- Reposted by Tania WongScientists have identified functional differences between human and mouse PD-1, which could impact preclinical research on cancer immunotherapies. Read more in #ScienceImmunology:
- Reposted by Tania WongImportant stuff Immune checkpoint inhibitors that block PD-1 pathway effective vs. many cancers New @IMMUNITY: impaired memory B cell development and IgG/A responses in humans and mice deficient in PD-1 signaling This dysregulation may explain ⬆️ risk of infection or autoimmunity in these patients
- Reposted by Tania WongInteresting, a fluorescent biosensors to illuminate arginine metabolism in cells, mice, and clinical samples. #Arginine #biosensor Lighting up arginine metabolism reveals its functional diversity in physiology and pathology: Cell Metabolism www.cell.com/cell-metabol...
