Neil Rajan
Professor of Dermatogenetics + Consultant Dermatologist #genetics #raredisease #dermatology Views are mine; he/him/his
- Reposted by Neil RajanNice preprint from @derm-scientist.bsky.social! Ubiquitin system is key for tissue architecture in CYLD cutaneous syndrome (CCS) skin tumours. "Comparative ubiquitinomics of human skin reveals insulin receptor ubiquitination as a regulator of collagen secretion." www.biorxiv.org/content/10.6...
- Reposted by Neil RajanA paper in Nature reports the details of a 60-year-old male individual from Germany who achieved sustained HIV remission after a stem cell transplant, the seventh-known case reported to date. go.nature.com/4rNjedx #medsky 🧪
- Absolutely! Let's keep building! @esdrorg.bsky.social ❤️❤️
- Now that @jamadermatology.com is here, joining @thejidjournal.bsky.social &otters, maybe #DermSky can start to grow #derm #dermatology #MedSky bsky.app/profile/did:...
- Reposted by Neil RajanThis case report describes a child with lesions that initially appeared as vesicles and progressively spread in a centrifugal pattern, forming concentric, spiraled rings. ja.ma/48dpF1s
- Reposted by Neil RajanWhy do whales and elephants have much lower rates of cancer than expected? "Species with a lower cancer prevalence and mortality risk are those with a higher presence of cooperative and caring habits, while the opposite is found....:" www.science.org/doi/10.1126/...
- Reposted by Neil RajanPersonalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The @fda.gov outlines a path to market entry for products where a randomized trial is not feasible. Learn more: nej.md/4nUQdcl
- Reposted by Neil RajanA 75-year-old woman with a history of infiltrating ductal carcinoma of the breast (previously treated with bilateral radical mastectomy and ongoing adjuvant hormonal therapy) presented to the dermatology clinic with a 1-year history of rash on the chest. 1/2 #MedSky #DermSky
- Reposted by Neil RajanPrevious multiple sclerosis, now the potential role of Epstein Barr virus for driving lupus (SLE) science.org/doi/10.1126/...
- Reposted by Neil RajanWith support from the NIHR Newcastle BRC, researchers Professor Neil Rajan @derm-scientist.bsky.social and Dr Mark Eisner from the Skin Disease, Oral Disease and Immunogenomics Theme attended the recent Ichthyosis Support Group (ISG) Family Day. 🔗 newcastlebrc.nihr.ac.uk/our-research...
- Reposted by Neil RajanSelena Gomez has shared her experiences living with #lupus since 2015 - writes Foundation-funded researcher @bcellsrosser.bsky.social for @uk.theconversation.com. To learn more, you can meet Dr Lizzy Rosser at our New Scientist Live stand (C20) on 18-19 October! shorturl.at/BusFG
- Reposted by Neil RajanReview | Spatial architecture of development and disease www.nature.com/articles/s41...
- Reposted by Neil RajanBREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize
- Reposted by Neil RajanWe're delighted to see immunologists once again recognised by the #NobelPrize! 🏆 Warm congratulations to the winners - their contributions have been vital in shaping our understanding of the immune system. More here: www.immunology.org/news/british...
- Reposted by Neil Rajan📅 Wed 3 Dec | Immunology in the balance with Prof. Lydia Lynch How does the immune system walk the line between protection & pathology? Join this session on the regulation of innate & adaptive immunity in infection, cancer, and inflammatory disease. #Immunology #BSI25
- www.genomicseducation.hee.nhs.uk/news/dermato... Calling all #dermatologists! We've just launched our new #GeNotes collection of resources to support you in accessing #GenomicTesting for your patients. Developed by Dr fellow dermatology experts, this is one not to miss!
- Reposted by Neil Rajan🚀 Excited to share our new Review in @jacionline.bsky.social ! We summarize the current evidence on IL-18 in atopic dermatitis. 📊 Links to barrier dysfunction & disease severity 💡 Potential biomarker & therapeutic target Read here 👉 www.jacionline.org/article/S009... #IL18 #atopicdermatitis
- Reposted by Neil RajanWe’re thrilled to introduce our four official Social Media Ambassadors for the 54th Annual ESDR Meeting! esdrmeeting.org/some2025/ @dr-hanat.bsky.social @dr-cganier.bsky.social @derm-scientist.bsky.social @drarmpit.bsky.social
- Reposted by Neil RajanVideos show pronuclear transfer, which was performed in a series of women with pathogenic mtDNA variants to reduce the transmission of these variants to their children. Read the full study about this method: nej.md/455eer6 #MedSky #Genetics
- Reposted by Neil RajanThe potential for 2 cancer drugs in combination to impact Alzheimer's disease as an outgrowth or single-cell RNA -seq, review of electronic health records from 1.4 million patients, and whittling down 1,300 potential repurposed drugs to 2. www.cell.com/cell/fulltex...
- Reposted by Neil RajanAmazing podcast on the mitochondrial donation babies. Great work by wonderful colleagues@mitonewcastle.bsky.social at @newcastleuni.bsky.social and the @lilyfoundation.bsky.social www.theguardian.com/science/audi...
- Reposted by Neil RajanOne-shot prime genome editing ("CRISPR 3.0") of the brain in vivo corrected AHC, a rare genetic disorder, in the mouse model. Another big step forward in the genome editing field. www.cell.com/cell/fulltex...
- Reposted by Neil Rajan🍷 Save the Date! 🍷 Join us for an evening of wine tasting at the historic Trinity House in support of North East skin research. 🗓️ Friday 14th November 2025 📍 Trinity House, Newcastle 🎟️ All proceeds go directly to the North East Skin Research Fund
- Reposted by Neil Rajan☀️ A fun Summer evening at The Magic Hat Cafe last night showcasing some of the fantastic skin research we have across the North East ✨ Thank you to everyone who attended and for supporting our North East Skin Research Fund
- Reposted by Neil RajanPremenopausal women are more likely than men to develop certain cancers. Pathways activated by the sex hormone responsible could be targeted in cancer therapies go.nature.com/445tJ0u
- Reposted by Neil RajanIncredible opening keynote by Charlie Swanton - spanning tumour initiation, aging, environmental exposure and much more 👏👏 #EACR2025 @charlesswanton.bsky.social @crick.ac.uk @helloeacr.bsky.social
- Reposted by Neil RajanFrom today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science go.nature.com/4kIRR01
- Reposted by Neil Rajan👋 Hello Bluesky! 🦋 We are the North East Skin Research Fund - bringing you the latest updates on skin research led by dermatologists and academics here in the North East of England! 🧴🧪 📸 Featuring our new logo #NESRF #northeastskin #northeast #northeastengland #skinresearch #dermatology
- Reposted by Neil Rajan“Cutaneous fibrofolliculomas and trichodiscomas in Birt-Hogg-Dubé syndrome: a review of therapeutic strategies” is now out in Dermatological Surgery! 🎉 journals.lww.com/dermatologic... A real testament to the BHD patient advocates and @derm-scientist.bsky.social who have championed this work!
- Reposted by Neil RajanReview Article: Cell Therapy and the #Skin: Great Potential but in Need of Optimization. Lee et al doi.org/10.1016/j.ji... #DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
- Reposted by Neil RajanA lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F #ASGCT2025 #MedSky @asgct.bsky.social
- Become a Social Media Ambassador for the 54th Annual @esdrorg.bsky.social ESDR Meeting! is a fantastic opportunity to contribute to the success of the meeting while building your professional network and showcasing your creativity. Apply Now! esdr.org/y-esdr/socia...
- Reposted by Neil RajanWe are delighted to introduce the recipients of the 2025 ISID Collegiality Awards. This year’s awardees Longlong Luo and Irene García Jiménez will be formally honored during the award ceremony at the SID 2025 Meeting in San Diego.
- Reposted by Neil RajanCelebrating 20 Years of the International Pachyonychia Congenita Consortium. Read Coulombe et al's News & Perspective Commentary in the April issue. doi.org/10.1016/j.ji... #DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
- The amazing Prof Chris Stewart @stewartlab.bsky.social gives his inaugural lecture👏🏾👏🏾👏🏾
- Reposted by Neil RajanHe’s back! The latest video in our partnership with @glaucomflecken.bsky.social summarizes the final, 10-year outcomes of the CheckMate 067 trial investigating nivolumab plus ipilimumab in advanced melanoma: #medsky #cardiosky
- Reposted by Neil RajanWe're just over a month out from our Annual Meeting. This year, thousands of #dermatology researchers, industry professionals and trainees are gathering in San Diego to learn + connect around breakthrough #skinscience. There's still time to register! Learn more at sidannualmeeting.org.
- Reposted by Neil RajanCYLD cutaneous syndrome is a rare genodermatosis caused by pathogenic variants in CYLD which results in the development of cylindromas, spiradenomas, and tricoepitheliomas. www.ncbi.nlm.nih.gov/books/NBK555...
- Reposted by Neil RajanCredit to supervisors @derm-scientist.bsky.social and @serenanikzainal.bsky.social and co-authors Dr. Koh, Ms. Holt, Dr. Husain, Dr. Namini, Dr. Mathew, Dr. Memari, and Dr. Davies for their hard work on this project 👏🏼 academic.oup.com/ced/advance-...
- Reposted by Neil RajanJoin us for an exclusive ISID Kitchen episode! 28 May, 1.30pm CET Free Registration lnkd.in/eTNaJajg We’re bringing together two leading experts, Rei Watanabe and Elaine Fuchs, to discuss the latest insights on #aging. Don't miss this opportunity to learn! #ESDRKitchen #Dermatology #SkinScience
- Reposted by Neil RajanJust returned from Antwerp after an inspiring board meeting! The ESDR stands out as one of the rare research societies that values the voices of young scientists/clinicians, shaping the future of skin research. Grateful to be part of a community dedicated to advancing knowledge & improving health!
- Reposted by Neil RajanPleased to be in the beautiful city of Antwerp for our board meeting ! Together, we are shaping the future of our society and actively preparing for our annual meeting which will take place here on September 10-13 ! We hope lots of you will come ! Many surprises ahead 🥳
- Reposted by Neil RajanWe are excited to announce an opportunity to become a Social Media Ambassador for the 54th Annual ESDR Meeting, taking place this September in Antwerp, Belgium! We are looking for 4 Social Media Ambassadors! 🔎 Who Can Apply? lnkd.in/eEsX6gR4
- Reposted by Neil RajanRebecca Calisi Rodríguez writes in Nature that higher-education establishments in the US must not be bullied into abandoning their mission of diversity, equity and inclusion. “Higher education must not back down. But to win this fight, universities need a plan.” #Academicsky 🧪
- Reposted by Neil RajanA new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them go.nature.com/4iCVnHL
- Reposted by Neil RajanWe're celebrating British Science Week, are you? We're delighted to support the #BSW25 activity packs, which you can download for free at the British Science Week website 🤩. Get involved in science👇 www.britishscienceweek.org and find out more about the work @britsciassoc.bsky.social does.
- Reposted by Neil RajanRead a new Perspective piece by cell biologist Vivek Malhotra on how TANGO1 constructs secretory pathways tailored to the size and quantity of cargo, and learn about the important open questions in the field. www.nature.com/articles/s41...
- Reposted by Neil RajanWe are pleased to announce that abstract submission for #ESDR2025 is now open lnkd.in/eWuzRYxz Basic guidelines can be found here: lnkd.in/eCJNJj4N Finally, but very importantly, travel grants are available for presenting authors aged 40 or under, & should be uploaded with your abstracts.
- Reposted by Neil RajanHow Can Spatial Transcriptomic Profiling Advance Our Understanding of Skin Diseases? See Kumaran et al's Review Article doi.org/10.1016/j.ji... #DermatologyJournal #dermatology #dermsky #dermatologists #dermresearch #dermscience #dermatologyresearch
- Reposted by Neil RajanI haven’t seen enough discussion coming from university leadership about elevating the importance of scientific communication in this new reality. Most of the public doesn’t even know what the NIH is or does.
- Reposted by Neil RajanThe addition of combined oral and topical antimicrobial therapy for male partners to treatment of women for bacterial vaginosis resulted in a lower rate of recurrence within 12 weeks than treatment of the woman alone. Full StepUp trial results and Research Summary: nej.md/3QJIVKn #MedSky #IDSky
- Reposted by Neil RajanResearch support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Prof Anna Greka @broadinstitute.org in a new Ground Truths podcast. Open-access, w/ transcript, video, no ads erictopol.substack.com/p/anna-greka...
- Reposted by Neil RajanIn two trials involving patients with chronic spontaneous urticaria, remibrutinib led to significantly greater reductions than placebo in itching and hives at week 12. Full results of the REMIX-1 and REMIX-2 trials: nej.md/41uQD07 #MedSky #DermSky
- Reposted by Neil RajanTo mark #InternationalWomensDay tomorrow, the #NatureReviews Collection on women's health has been updated. Click below to read articles on various aspects of women's health, including brand new Reviews from @natrevcardiol.bsky.social and @natrevgastrohep.bsky.social go.nature.com/30kDWG3
- Reposted by Neil RajanJ.P. Flores, a core organizer for today's rallies and a bioinformatics researcher at the University of North Carolina, Chapel Hill, told Nature: “March 7 is the beginning — I don’t necessarily see it as the endpoint.” #StandUpForScience www.nature.com/articles/d41...
