Joanna Chustecki
Postdoc Associate at University of Oxford, currently studying mitochondrial dynamics in plant development
Also on the bird app
- Reposted by Joanna ChusteckiPhD opportunity in the newly minted RO2T Respiration Group! Please share! Interested in root biology, oxygen dynamics, imaging & modelling? We’re recruiting a PhD student at the University of Nottingham. Deadline 15th February. jobs.nottingham.ac.uk/Vacancy.aspx... #plantscijobs #plantscience
- Reposted by Joanna ChusteckiIn their Review, Rahul Kumar Verma, Somya Madan and Richa Rikhy discuss mitochondrial dynamics and signalling in stem cell differentiation. journals.biologists.com/jcs/article/...
- Reposted by Joanna ChusteckiGreat collaboration with the Sanchez-Puerta lab and colleagues! @lfceriotti.bsky.social @organelledchaos.bsky.social @jumpinggenomes.bsky.social @chusteckisci.bsky.social @achristensenphd.bsky.social (and others not on bsky) www.biorxiv.org/content/10.6...
- More evidence for the sphere of influence model- local mtDNA quality determines local mitochondrial function, even when part of an interconnected network- and drives selection! Beautiful work
- How do cells assess mtDNA quality? Local ATP and membrane-potential gradients reflect mtDNA integrity and drive intracellular purifying selection. We introduce FAST, a scalable mtDNA QC assay in S. cerevisiae. Great collaboration with the Schmoller Lab. journals.plos.org/plosgenetics... 🧬⚡
- Reposted by Joanna Chustecki1. Apply for one of the positions below (lab or theory) by Jan 18th 2. Learn interdisc skills and discover cool new things about how mitochondria move and socialise 3. Explore some of Norway's beautiful nature (both the below, Rundemanen and Gullfjellet, <10km from work)
- ‼️Two new PhD positions open! One experimental, one modelling, exploring these beautiful collective dynamics in mitochondria across species. 🇳🇴, good pay, full staff benefits. [Shares much appreciated] Lab: www.jobbnorge.no/en/available... Modelling: www.jobbnorge.no/en/available...
- Apply here for an incredible mentor, cool science and a beautiful city in which to work! ✨
- ‼️Two new PhD positions open! One experimental, one modelling, exploring these beautiful collective dynamics in mitochondria across species. 🇳🇴, good pay, full staff benefits. [Shares much appreciated] Lab: www.jobbnorge.no/en/available... Modelling: www.jobbnorge.no/en/available...
- Reposted by Joanna Chustecki🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA
- Reposted by Joanna ChusteckiSo happy to see this work finally online! In this Research Review, I discuss the emerging roles of H3K27me3 writers (the enzymes that lay it down) and erasers (the enzymes that remove it) in controlling plant adaptation 🌿🌡️❄️🦠 nph.onlinelibrary.wiley.com/doi/10.1111/...
- Check out the editorial 'Plant Mitochondrial Biology' special issue; home to our paper 'Running on empty: Mitochondria Without DNA Exhibit Differential Motility&Connectivity' @achristensenphd.bsky.social Editorial onlinelibrary.wiley.com/doi/10.1111/... Paper onlinelibrary.wiley.com/doi/10.1111/...
- Reposted by Joanna ChusteckiWe just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji. It ships many new features, detailed below, but that are articulated around the following:
- Reposted by Joanna Chustecki🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/
- A privilege to attend the 9th annual Computational Plant Biology workshop last week at @slcuplants.bsky.social heard inspiring talks, got direct help and advice with pipeline bottlenecks and explored some very pretty places!
- Nice to see a small summary of our research findings in the Plantae Research Weekly! ☺️🌱
- Plant Science Research Weekly -- Running on empty: How does the absence of mtDNA shape mitochondrial movement and connectivity? (Physiologia Plantarum) @ChusteckiSci.bsky.social (Summary by Irene I. Ikiriko) buff.ly/HOvSCtO #PlantaePSRW
- Reposted by Joanna ChusteckiThis might be one of the simplest images I captured, but very fascinating nonetheless, as it shows how tight the cytoplasm in a plant cell is. The cytosol and all other organelles are squished between the plasma membrane (magenta) and the central vacuole (its membrane is green) #MicroscopyMonday
- Reposted by Joanna ChusteckiI'm happy to share new work in collaboration with Elena Koslover's lab! First author Keaton developed a mathematical framework for diffusion of soluble material through mitochondrial networks. Then, Lewis lab PhD candidate Camryn used live cell imaging to parameterize... 1/3
- Reposted by Joanna ChusteckiMitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box. Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
- Reposted by Joanna ChusteckiCytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations (Kin Pan Chung) doi.org/10.1093/plph... #PlantScience
- The only meeting I’ve ever been to with a fun fair at night! #brumforever #NGS2025
- It’s been a wonderful meeting so far at #NGS2025 the ECR community is a great place to be right now, and we’ve had some fascinating talks and workshops. Loved presenting my work on mtDNA and mito dynamics #plantscience
- Reposted by Joanna ChusteckiPlease RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏 www.imperial.ac.uk/media/imperi...
- Got papped yesterday at the @biology.ox.ac.uk research showcase spreading the good word about mitochondrial dynamics! So fun being in the new LaMB building and interacting with psych/bio colleagues 🌱🧠 (You can check out the paper I was soapboxing about here: onlinelibrary.wiley.com/doi/10.1111/...)
- Reposted by Joanna ChusteckiCongrats, Joanna! New article out in collaboration with our Microscopy Core!
- An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱 onlinelibrary.wiley.com/doi/10.1111/... (1/9)
- Reposted by Joanna ChusteckiIn their Review, Sangheeta Bhattacharjee and Benu Brata Das discuss the roles of topoisomerases in mtDNA maintenance and repair, and highlight their potential as therapeutic targets. journals.biologists.com/jcs/article/...
- Reposted by Joanna ChusteckiProudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
- Reposted by Joanna ChusteckiThank you to David Macherel, Jose Gualberto and Hakim Mireau for organizing the 2024 ICPMB meeting and the special issue of Phys. Plant. And to Olivier Keech, Allan Rassumsson and Olivier Van Aken for organizing the 2022 ICPMB meeting where I first met Joanna and the seeds of this work germinated.
- An exciting day! Our latest work is now out; we ask the question, are there any differences between plant mitochondria with and without mtDNA? 🌱 onlinelibrary.wiley.com/doi/10.1111/... (1/9)
- Plant mitochondria are very different from animals/yeast, existing mostly as bacteria-shaped individuals. They have very large genomes, full of non-coding sequences, and fascinatingly, not all mitochondrial carry mtDNA. (2/9)
- We started by characterising exactly how many mitos per cell have mtDNA (not before quantified per cell), using SYBR green as a marker in fixed tissue. (3/9)
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- Reposted by Joanna ChusteckiHappy to share that this study is now published. Check it out! journals.plos.org/plosgenetics...
- Reposted by Joanna ChusteckiI'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
- Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
- Reposted by Joanna ChusteckiHow do cells achieve an optimal mitochondrial distribution? Excited to share a piece of this puzzle: www.science.org/doi/10.1126/...
- Nice to be back in sunny Münster to help out with the GoPMF Imaging Workshop 2025!
- I hope lots of #GoPMF folks liked my intro to #Trackmate !
- Reposted by Joanna ChusteckiMITOtalks this week
- I answered 33 questions for the Women in Research Fellowship Team! It has been a wonderful opportunity, I’d really recommend the #WiRE fellowship to any women ECRs looking at moving to Germany! wire-uni-muenster.de/plant-cells-...
- It was a lot of fun to answer these and to take these pictures in the lab with the talented Niko at #WiRE 🌱
- Here's a little intro I wrote for my time at the University of Münster in the @schwarzlanderlab.bsky.social 🌱 There will be a longer form interview coming soon!🎙️ wire-uni-muenster.de/dr-joanna-ch... (Studying mitos, not birds!) #fellowship #WiRE
- Can’t wait to get into these preprints! Incredible insight and experimental/modelling approaches taken
- Reposted by Joanna ChusteckiA new biosensor is born 👼 The NAPstar family of genetically-encoded sensors for live NADP redox monitoring🔋🪫 Jointly with the Morgan lab & @riemerlab.bsky.social we looked in vitro, in yeast, plants & mammalian cells 🧪🦠🧫🌱 Where to go next? @naturecomms.bsky.social doi.org/10.1038/s414...
- Reposted by Joanna ChusteckiGreat collab with @chusteckisci.bsky.social and the @achristensenphd.bsky.social + Sanchez-Puerta labs!
- Congratulations to Rachael on this new story out now in PNAS! Delving into translational machinery retargeting across different plant species- plastid presence is the key 🗝️🔬🌱 it was a great experience helping out on the ‘scope for this project and working with some awesome scientists 🥳
- Second paper from the lab out today (woohoo!). This one led by Rachael DeTar. Check out what happens to mito+plastid translation machinery in plants that have lost photosynthesis! Published in @pnas.org: www.pnas.org/doi/10.1073/... Also available on bioRxiv: www.biorxiv.org/content/10.1...
- Reposted by Joanna ChusteckiHere's a mitochondrial "social network" (tracking encounters) emerging over time from their collective dynamics in a plant cell. This picture helps us understand their capacity to share and exchange biomolecules 🔬🌱🫂 Read more www.sciencedirect.com/science/arti...; pubmed.ncbi.nlm.nih.gov/34015261/
- Reposted by Joanna ChusteckiA revised version of our paper on Arabidopsis mitochondrial motion. Now using two methods of imaging mtDNA! Wonderful work by @chusteckisci.bsky.social "Running on empty: Mitochondria without mtDNA exhibit differential motility and connectivity." www.biorxiv.org/content/10.1...
- Reposted by Joanna ChusteckiSo cool! Understanding how mtDNA regulates their movement inside cells will be possible with tools like these!
- Hey blue skies- We have updated our latest #BioRxiv paper- We found that #mitochondria in #plants without mtDNA move and connect differently to those with mtDNA! Now featuring two different methods of measuring mtDNA and mitochondrial motility. Check it out: www.biorxiv.org/content/10.1...
